scholarly journals Iris surface features and anterior chamber depth in Chinese adolescents

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Chen-Wei Pan ◽  
Yu-Xi Qian ◽  
Jun Li ◽  
Hua Zhong

Abstract Background We aim to determine the association of iris surface features including crypts, color and contraction furrows with anterior chamber depth (ACD) in a school-based sample of Chinese teenagers. Methods Totally, 2346 students aged 13 to 14 years in Mojiang located in the Southwestern part of China contributed to this analysis. Iris surface features were graded based on standardized slit-lamp photographs. Ocular biometric parameters including ACD were measured using an IOL Master. Generalized estimating equation was incorporated in the linear regression models to assess the relationship between iris surface features and ACD. Results A significant trend of increasing ACDs with more contraction furrows were observed. On average, the mean ACD was 3.03 mm in participants with contraction furrows of grade 1 while it was 3.10 mm in those with grade 3 (mean difference, 0.07 mm, P = 0.01). Adjusting for other potential confounders such as gender, height and weight did not significantly changed the associations. Compared with individuals with contraction furrows of grade 1, those with grade 3 had a greater ACD of 0.06 mm (95% confidence interval: 0.01, 0.11) in multivariate-adjusted model. There were no significant relationships between ACD and iris crypts or color. (P > 0.10). Conclusions More iris contraction furrows are associated with greater ACDs while the association with iris color and crypts were not significant.

2019 ◽  
pp. bjophthalmol-2018-313357 ◽  
Author(s):  
Chen-Wei Pan ◽  
Chaofu Ke ◽  
Dan-Ning Hu ◽  
Jun Li ◽  
Hua Zhong

Background/aimsIris colour might contribute to refractive development, but it is uncertain whether it is related to astigmatism. We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle schools aged 13 to 14 years in Southwestern China participated in the study. We obtained standardised slit-lamp photographs and developed a grading system assessing iris colour (higher grade denoting darker). Astigmatism was defined as a cylinder power of more than 0.50, 0.75 or 1.00 dioptre (D). Logistic regression models with generalised estimating equation were fitted to assess the relationship between iris colour and astigmatism, accounting for the correlation between both eyes. ORs and 95% CIs were presented.ResultsThe overall prevalence of astigmatism for three different definitions was 30.4% (95% CI 28.6% to 32.2%) (<−0.5 D), 12.7 % (95% CI 11.3% to 14.0%) (<−0.75 D) and 5.3% (95% CI 4.4% to 6.2%) (<−1.0 D), respectively. In multivariate analysis adjusting for the effect of gender and height, darker iris colour was associated with an increasing trend of astigmatism (p for trend <0.05). Compared with individuals with iris colour of grade 4 or 5 (the darkest), those with grade 1 or 2 (the lightest) were significantly less likely to be affected by astigmatism (<−0.75 D) in gender-adjusted model (OR 0.67) and multivariate-adjusted model (OR 0.72).ConclusionDarker iris colour might be a risk factor for astigmatism in Chinese adolescents.


2021 ◽  
Vol 8 ◽  
Author(s):  
Peng He ◽  
Li-jie He ◽  
Chen Huang ◽  
Jin-ping Hu ◽  
Shi-ren Sun

Objective: We sought to explore if there is an association between neutrophil-to-lymphocyte ratio (NLR) and treatment failure in patients with peritoneal dialysis-associated peritonitis (PDAP).Methods: Our cohort involved 337 episodes of PDAP experienced by 202 patients who were undergoing continuous ambulatory peritoneal dialysis at a single center from 1 July 2013 to 30 June 2018. The exposures were log-transformed NLR and a categorical variable grouped by the tertiles of NLR levels (T1, &lt;3.75; T2, 3.75–6.53; and T3, &gt;6.53) at baseline. Generalized estimating equation (GEE) and restricted cubic spline (RCS) analyses were done to determine the association between NLR and treatment failure, defined as catheter removal or all-cause mortality during therapy.Results: After adjusting for other potential predictors, the log-transformed NLR exhibited an incremental relationship with the risk of treatment failure (odds ratio, 1.82; 95% confidence interval, 1.05–3.15). RCS analyses showed that the relationship was positively and linearly correlated (P for nonlinearity = 0.104). As a three-level categorical variable, in reference to T1, the T3 of NLR showed a 3.41-fold increased venture of treatment failure in fully adjusted model. Subgroup analyses suggested that the prognostic relevance of NLR in PDAP was particularly significant in gram-negative peritonitis.Conclusions: A greater level of NLR at baseline was remarkably associated with a higher incidence of treatment failure among PDAP episodes regardless of other potential risk factors.


2021 ◽  
Author(s):  
Кирилл Борисович Першин ◽  
Надежда Федоровна Пашинова ◽  
Иван Александрович Лих ◽  
Александр Юрьевич Цыганков ◽  
Абдусамад Аристанович Ахраров

Aim. Determination of the relationship between the anterior chamber depth and the and accuracy of the IOL optical power calculating in the eyes with an axial length of less than 22 mm. Materials and methods. A total of 86 patients (133 eyes) with a short axis (from 18.54 to 21.98 (20.7 0.9) mm) were included in the study. Group I (n=40) consisted of patients with an ACD of less than 2, 5 mm. Group II (n=49) included patients with ACD from 2.5 to 2.9 mm Group III (n=44) included patients with ACD greater than 2.9 mm The calculation of the IOL optical power was carried out according to the formula SRK / T, retrospective comparison - according to the formulas Hoffer-Q, Holladay II, Olsen, Haigis and Barrett Universal II. Results. In group I, there were no significant differences when comparing MedAE for the six formulas (p0.05). The highest MedAE values ​​(0.51 and 0.49, respectively) and the smaller MNE range (-0.03 0.89 and -0.01 0.97, respectively) are shown for the formulas Haigis and Barrett Universal II. In group II, the MedAE for the Haigis formula was 0.45, for SRK / T and Olsen it was 0.59 and 0.66. For the Haigis formula, the lowest MNE value (0.05 0.69) is shown. In group III, no significant differences were found when comparing the average values ​​of MedAE (0.05). The lowest MedAE (0.17) and the best MNE values ​​(-0.01 0.58) are shown for the Haigis formula, while the SRK / T formula was characterized by the highest MedAE (0.37). In group II, the refractive index 0.25 and 0.50 D for the Haigis formula was significantly higher. Conclusion. For eyes with an ACD of less than 2.4 mm, none of the formulas showed a significant advantage, while with an ACD of 2.4-2.9 mm and higher, the use of the Haigis formula is recommended, and the SRK / T formula showed the worst result. The data obtained dictate the need to review existing standards for calculating the IOL optical power in patients with short eyes depending on ACD.


2016 ◽  
Vol 8 (12) ◽  
pp. 133 ◽  
Author(s):  
Neda Nakhjavanpour ◽  
Abolfazl Payandeh ◽  
Majid Rajabi ◽  
Vahid Shoja

<p>Anterior segment eye parameters are essential factors in diagnosis, screening and management of abnormal ocular conditions. Based on the previous studies, they might differ from one race or population to another. Sistan-and-Baluchestan province, the southeast of Iran, has special weather conditions and race, plus lack of research on these diagnostic factors. Hence, the objective of the present study was to assess anterior segment parameters using pentacam in this area. 800 eyes of subjects which had been referred to the Al-Zahra eye hospital of Zahedan, the capital city of the province, for corneal refractive surgery from October 2014 to March 2015 participated in this research. 95% confidence limits for mean of central corneal thickness, anterior chamber depth and volume were (536.02, 541.20), (3.13, 3.18) and (187.63, 192.58) respectively. Multiple linear regression models showed a lower mean central corneal thickness, and maximum/minimum of keratometry, for males than females, adjusting for age and spherical equivalent. Inversely, anterior chamber depth, and volume were more in males. In order to diagnosis and treating ocular diseases which have effect on retinal thickness, precisely specification of predictive factors is highly needed.</p>


2007 ◽  
Vol 144 (2) ◽  
pp. 325-326 ◽  
Author(s):  
Seang-Mei Saw ◽  
Tien Y. Wong ◽  
Steven Ting ◽  
Athena W.P. Foong ◽  
Paul J. Foster

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Shuning Li ◽  
Jing Jiang ◽  
Yiquan Yang ◽  
Gewei Wu ◽  
Shi-Ming Li ◽  
...  

Background. To determine the range of pupil size that has the largest iris volume in normal eyes. Methods. 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. Results. The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x2 + 8.8429x + 16.423, R2 = 0.26886). The largest IV occurred at PS between 3 and 4 mm. Conclusions. The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Ying Yuan ◽  
Zhengwei Zhang ◽  
Jianfeng Zhu ◽  
Xiangui He ◽  
Ergang Du ◽  
...  

Purpose. To investigate the changes of anterior segment after cycloplegia and estimate the association of such changes with the changes of refraction in Chinese school-aged children of myopia, emmetropia, and hyperopia.Methods. 309 children were recruited and eligible subjects were assigned to three groups: hyperopia, emmetropia, or myopia. Cycloplegia was achieved with five cycles of 0.5% tropicamide. The Pentacam system was used to measure the parameters of interest before and after cycloplegia.Results. In the myopic group, the lenses were thinner and the lens position was significantly more posterior than that of the emmetropic and hyperopic groups in the cycloplegic status. The correlations between refraction and lens thickness (age adjusted;r=0.26,P<0.01), and lens position (age adjusted;r=-0.31,P<0.01) were found. After cycloplegia, ACD and ACV significantly increased, while ACA significantly decreased. Changes in refraction, ACD, ACV, and ACA were significantly different among the three groups (P<0.05, all). Changes of refraction were correlated with changes of ACD (r=0.41,P<0.01).Conclusions. Myopia presented thinner lenses and smaller changes of anterior segment and refraction after cycloplegia when compared to emmetropia and hyperopia. Changes of anterior chamber depth were correlated with refraction changes. This may contribute to a better understanding of the relationship between anterior segment and myopia.


2021 ◽  
Vol 75 (Supplement_2) ◽  
pp. 7512505164p1-7512505164p1
Author(s):  
Diana Feldhacker ◽  
Reilly Cosgrove ◽  
Benjamin Feiten ◽  
Kayleigh Schmidt ◽  
Marissa Stewart

Abstract Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations. Fifty-three kindergarten and first-grade students were screened to examine the relationship between primitive reflexes and scholastic performance. Overall, 100% of participants had retention of at least one reflex. Results indicated statistically significant relationships between reflexes and areas of academic performance. Further research is warranted to understand why reflexes are not being integrated and how school-based OTs ought to use these findings. Primary Author and Speaker: Diana Feldhacker Additional Authors and Speakers: Reilly Cosgrove, Benjamin Feiten, Kayleigh Schmidt, and Marissa Stewart


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