scholarly journals Osteomyelitis in Immunocompromised children and neonates, a case series

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bryan Foong ◽  
Kenneth Pak Leung Wong ◽  
Carolin Joseph Jeyanthi ◽  
Jiahui Li ◽  
Kevin Boon Leong Lim ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Staphylococcus Aureus ◽  
Palliative Care ◽  
Stenotrophomonas Maltophilia ◽  
Burkholderia Pseudomallei ◽  
Bone Growth ◽  
Case Series ◽  
Immune Recovery ◽  
Prolonged Administration ◽  
Infectious Disease Service

Abstract Background Osteomyelitis in immunocompromised children can present differently from immunocompetent children and can cause devastating sequelae if treated inadequately. We aim to review the aetiology, clinical profile, treatment and outcomes of immunocompromised children with osteomyelitis. Methods Retrospective review of all immunocompromised children aged < 16 years and neonates admitted with osteomyelitis in our hospital between January 2000 and January 2017, and referred to the Paediatric Infectious Disease Service. Results Fourteen patients were identified. There were 10 boys (71%), and the median age at admission was 70.5 months (inter-quartile range: 12.3–135.0 months). Causal organisms included, two were Staphylococcus aureus, two were Mycobacterium bovis (BCG), and one each was Mycobacterium tuberculosis, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Burkholderia pseudomallei and Rhizopus sp. One patient had both Clostridium tertium and Clostridium difficile isolated. Treatment involved appropriate antimicrobials for a duration ranging from 6 weeks to 1 year, and surgery in 11 patients (79%). Wherever possible, the patients received treatment for their underlying immunodeficiency. For outcomes, only three patients (21%) recovered completely. Five patients (36%) had poor bone growth, one patient had recurrent discharge from the bone and one patient had palliative care for underlying osteosarcoma. Conclusions Although uncommon, osteomyelitis in immunocompromised children and neonates can be caused by unusual pathogens, and can occur with devastating effects. Treatment involves prolonged administration of antibiotics and surgery. Immune recovery also seems to be an important factor in bone healing.

scholarly journals Cervical melioidosis: an infrequent cause of neck abscess

2020 ◽  
Vol 6 (2) ◽  
pp. 388
Author(s):  
Nurul Alya Binti Azwan ◽  
Ram Kumar Sharma Shanmugam ◽  
Kong Yin Teng
Keyword(s):  
Infectious Disease ◽  
Blood Culture ◽  
Burkholderia Pseudomallei ◽  
Case Series ◽  
Morbidity Rate ◽  
Gram Negative ◽  
Mortality And Morbidity ◽  
Neck Abscess ◽  
Culture And Sensitivity ◽  
Soil And Water

<p class="abstract">Melioidosis remains as one of the rare infectious disease with high mortality and morbidity rate. It is caused by the gram-negative bacilli <em>Burkholderia pseudomallei</em> found in soil and water. We would like to share our experience of four case series that had been collected in Bintulu Hospital, Sarawak over a period of eight months starting from June 2018- January 2019. A total of four patients presented with neck abscess where the pus culture and sensitivity show <em>B. pseudomallei</em> but the blood culture and sensitivity show no culture or growth.</p>

Association of Stenotrophomonas maltophilia infection with lower airway disease in the horse: A retrospective case series

2010 ◽  
Vol 186 (3) ◽  
pp. 358-363 ◽  
Author(s):  
Lotte Winther ◽  
Rikke Munk Andersen ◽  
Keith E. Baptiste ◽  
Bent Aalbæk ◽  
Luca Guardabassi
Keyword(s):  
Stenotrophomonas Maltophilia ◽  
Case Series ◽  
Airway Disease ◽  
Lower Airway ◽  
Retrospective Case ◽  
Retrospective Case Series

scholarly journals Case series of Community Acquired Methicillin Resistant Staphylococcus Aureus

2018 ◽  
Vol 73 ◽  
pp. 159
Author(s):  
S. Lupo ◽  
N. Tamagnone ◽  
M.S. Rodriguez ◽  
A. Co ◽  
M. Vera Blanch ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Case Series ◽  
Methicillin Resistant

scholarly journals Infectious morbidity and resource provision for infectious disease service in municipal districts of the Republic of Tatarstan

2017 ◽  
Vol 98 (6) ◽  
pp. 1029-1033 ◽  
Author(s):  
A M Galieva ◽  
A Yu Vafin ◽  
I E Kravchenko ◽  
A N Galiullin
Keyword(s):  
Infectious Disease ◽  
Rural Areas ◽  
Well Being ◽  
Annual Reports ◽  
Rural People ◽  
Infectious Morbidity ◽  
Part Time ◽  
The Republic ◽  
Infectious Disease Service ◽  
Administrative Center

Aim. To conduct analysis of resource provision for medical care for patients with infectious pathology and to study primary infectious morbidity at the level of municipal districts of the Republic of Tatarstan. Methods. Study of primary infectious morbidity according to official statistics of the Federal Service for Supervision of Consumer Rights Protection and Human Well-Being in the Republic of Tatarstan based on form No. 2 with extracting data in 495 units, annual reports of Infectious Disease Service of the Ministry of Health of the Republic of Tatarstan for 2005-2015 - 66 units. The analysis of resource provision according to the central regional hospitals data, with extracting data in 70 units. Results. During the period of 2005-2015 the highest rates of primary infectious morbidity were observed in municipal districts where the administrative center is a city (13 054.01 per 100 000 population), the lowest - in rural areas (7953.6). The level of infectious morbidity in municipal districts is significantly lower than in average across the Republic of Tatarstan (р ˂0.05). 3 municipal districts having different types of administrative center are studied: Zainsky (urban population 72%), Apastovsky (rural people 73.9%), Drozhzhanovsky (rural people 100%) districts. The highest level of infectious morbidity in Zainsky District (2005 - 10 510; 2015 - 11 800.85 per 100 000 population), Apastovsky (7600.0 and 3612.44) and Drozhzhanovsky district (1629.68 and 4765.84). Differences in resource provision for infectious disease service are established: Zainsky district (there is an infectiologist, infectious beds, infectious disease office, specialized laboratory), Apastovsky district (service in infectious disease office is provided by part-time infectiologist), Drozhzhanovsky district (service in infectious disease office is provided by a nurse). In Drozhzhanovsky and Apastovsky districts there are no infectious beds and specialized laboratories. Conclusion. Level of infectious morbidity in municipal districts of the Republic of Tatarstan is closely related to the type of municipal district and resource provision for infectious disease service.

scholarly journals Stenotrophomonas maltophilia: Descripción de un agente altamente infeccioso

2020 ◽  
Vol 47 (2) ◽  
pp. 114-118
Author(s):  
Adriana Lisette Daza Hernández ◽  
Héctor Manuel Prado Calleros ◽  
Angélica Contreras Muñoz
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Stenotrophomonas Maltophilia ◽  
Acinetobacter Spp

Stenotrophomonas maltophilia es una bacteria oportunista que causa diversos tipos de infecciones asociadas a la atención sanitaria en pacientes debilitados, especialmente en aquellos que previamente han recibido antimicrobianos de amplio espectro. Stenotrophomonas maltophilia se posiciona hoy en día como un patógeno nosocomial de ámbito general, añadiéndose a otros multirresistentes como Staphylococcus aureus, Acinetobacter spp. y Pseudomonas aeruginosa. Presentamos este caso dado que es el primero que encontramos en nuestro servicio, simulando una infección recurrente por micobacterias, con el objetivo de demostrar el protocolo utilizado para diagnóstico y tratamiento; Este germen es poco frecuentemente reportado, siendo todos en inmunosuprimidos o con tratamiento antibiótico prolongado. Este agente infeccioso debe considerarse e incluirse entre los diagnósticos diferenciales de conglomerados ganglionares abscedados. En pacientes con inmunosupresión sospechada o conocida es necesario descartar la presencia de microorganismos oportunistas, para poder proveerle un adecuado diagnóstico y tratamiento específico

Purulent Pericarditis Due to Paronychia in a 16-Month-Old Child: A Nail-Biting Story

2018 ◽  
Vol 11 (4) ◽  
pp. NP125-NP128
Author(s):  
Neha Bansal ◽  
Henry L. Walters ◽  
Daisuke Kobayashi
Keyword(s):  
Infectious Disease ◽  
Staphylococcus Aureus ◽  
Cardiac Tamponade ◽  
Constrictive Pericarditis ◽  
Median Sternotomy ◽  
Purulent Pericarditis ◽  
Surgical Interventions ◽  
Nail Biting ◽  
Significant Mortality

Purulent pericarditis is a rare infectious disease with significant mortality, even in the modern antibiotic era. The presenting signs can often be subtle and patients can deteriorate rapidly with cardiac tamponade. We report a previously healthy 16-month-old female who developed purulent pericarditis associated with paronychia and sepsis caused by methicillin-sensitive Staphylococcus aureus. In addition to antibiotic treatment, she required emergent pericardiocentesis for cardiac tamponade, followed by two surgical interventions including full median sternotomy incision and partial pericardiectomy. At 4-month follow-up, she did well with no evidence of constrictive pericarditis on echocardiogram.

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