Epilepsy and other seizure disorders in acute psychiatric inpatients

Abstract Background It is well known that patients with epilepsy have a high rate of psychiatric comorbidity. However, studies exploring epilepsy in psychiatric cohorts are scarce. The aim of this study was to examine the prevalence of seizure disorders in acute psychiatric inpatients. Methods This is a cross-sectional study performed in a catchment-area based acute psychiatric department. All patients (age > 18) admitted during September 2011 - March 2012 were eligible for inclusion. Consenting patients were screened for a life-time history of epilepsy or seizures using self-reported questionnaire data and diagnostic codes for epilepsy in hospital and National registries. Patients scoring positive to one or more of these screening criteria underwent a thorough diagnostic validation (chart review), and the seizure disorders were classified as epilepsy, acute symptomatic seizures and/or psychogenic non-epileptic seizures according to current definitions. Results A total of 380 out of 591 (64.3%) consecutively admitted patients consented to participate in the study. Eighty-nine patients (23.4%) scored positive to one or more screening criteria. Fifteen (3.9%) were classified with epilepsy, 21 (5.5%) with acute symptomatic seizures and 9 (2.4%) with psychogenic non-epileptic seizures. Conclusions This is the first study to report on the prevalence of seizure disorders in acute psychiatric inpatients. The life-time prevalence of epilepsy in this cohort of patients is five – six times as high as reports in the general population. These findings underscore the need for the clinical psychiatrist to have comprehensive knowledge on the interface between epileptology and psychiatry. Trials registration ClinicalTrials.gov identifier NCT01415323.

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Acute symptomatic seizures and ventricular fibrillation - a multimodality approach to a rare complication of myocardial infarction. Case report

Romanian Journal of Cardiology ◽

10.47803/rjc.2021.31.1.90 ◽

2021 ◽

Vol 31 (1) ◽

pp. 90-96

Author(s):

Miruna Florina Stefan ◽

Stefania Lucia Magda

Keyword(s):

Myocardial Infarction ◽

Case Report ◽

Ventricular Fibrillation ◽

Rare Complication ◽

Epileptic Seizures ◽

Diffi Cult ◽

Symptomatic Seizures ◽

The Right ◽

Multimodality Approach ◽

Acute Symptomatic Seizures

Background – 6-8% of patients with acute myocardial infarction still develop ventricular arrhythmias (VA), although their incidence has lowered due to prompt antiischemic treatment. VA might determine sometimes acute symptomatic seizures. Case report – A 44-year old male was admitted to our unit with acute inferior myocardial infarction. Emergency coronary angiography was performed and revealed acute occlusion of the right coronary artery. The procedure was complicated by coronary dissection, which was sealed, with good fi nal results. After admission in the acute coronary unit, the patient developed ventricular fibrillation. He was successfully resuscitated, but developed ongoing tonic-clonic seizures, terminated after intravenous administration of several anticonvulsivant drugs. We investigated the patient for epilepsy and for other pathologies that could explain both the VA and the seizures. All investigations were within normal range. Conclusion – Differential diagnosis between hypoxic and epileptic seizures is diffi cult and important, because it further influences patient management. Cardiac arrhythmias are a rare precipitating factor for acute symptomatic seizures, due to hypotension-induced cerebral hypoxemia. Our case illustrates the value of a multimodal approach of rare complication of a myocardial infarction.

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Epileptic events in the XIX century as reported by the Brazilian Royal Family

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2010000300029 ◽

2010 ◽

Vol 68 (3) ◽

pp. 472-474

Author(s):

Marleide da Mota Gomes ◽

Heber de Souza Maia-Filho

Keyword(s):

Medical Knowledge ◽

Family Health ◽

Epileptic Seizures ◽

Febrile Convulsion ◽

Royal Family ◽

Generalized Seizures ◽

History Of ◽

Symptomatic Seizures ◽

Generalized Epilepsy ◽

Acute Symptomatic Seizures

Members of the Brazilian Royal Family carry a rich medical history of epileptic seizures and alike. OBJECTIVE: To present the medical knowledge about epilepsy by the time of the Brazilian Empire, as reported by the royal family. METHOD: Narrative review of historical facts about D. Pedro I's family health. RESULTS: The Royal Family, since D. João VI's generation is full of members with epilepsy or acute symptomatic seizures of different etiologies. CONCLUSION: The reported cases suggest that Dom Pedro I's family presented epilepsy with tonic-clonic generalized seizures, besides psychogenic, organic non epileptic events and acute symptomatic seizures. As a whole, this familial epilepsy could fit the diagnosis of generalized epilepsy with febrile convulsion plus.

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Neurological Manifestations of Sanjad–Sakati Syndrome: New Three Reported Cases from Tunisia

Journal of Pediatric Neurology ◽

10.1055/s-0039-1698753 ◽

2019 ◽

Vol 18 (02) ◽

pp. 126-130

Author(s):

Nadia Bouattour ◽

Fatma KamounFeki ◽

Wafa Bouchaala ◽

Siham Ben Nsir ◽

Chahnez Triki

Keyword(s):

Autosomal Recessive ◽

Epileptic Seizures ◽

Proper Treatment ◽

Neurological Manifestations ◽

Poor Growth ◽

Neurodevelopmental Delay ◽

Dysmorphic Features ◽

Tunisian Patients ◽

Symptomatic Seizures ◽

Acute Symptomatic Seizures

AbstractSanjad–Sakati syndrome (SSS), or hypoparathyroidism–mental retardation dysmorphism syndrome, is a rare autosomal recessive congenital disorder characterized by congenital hypoparathyroidism, growth and neurodevelopmental delay, acute symptomatic seizures due to hypocalcemia, and dysmorphic features. The syndrome is underdiagnosed, and neurological manifestations are not previously described. We report three Tunisian patients with SSS revealed by acute symptomatic hypocalcemic epileptic seizures. Despite the well-controlled seizures, patients tend to continue having poor growth and neurological outcome. The diagnosis of SSS allowed for proper treatment of the patients, prevented associated comorbidities, and provided genetic counseling to their families.

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Acute symptomatic seizures during haematopoietic stem cell transplantation

Epilepsia and paroxyzmal conditions ◽

10.17749/2077-8333/epi.par.con.2021.049 ◽

2021 ◽

Vol 13 (1) ◽

pp. 65-82

Author(s):

Ya. B. Skiba ◽

A. Yu. Polushin ◽

M. Yu. Prokudin ◽

M. D. Vladovskaya ◽

A. D. Kulagin

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Epileptic Seizures ◽

Haematopoietic Stem Cell ◽

Hematopoietic Stem ◽

Symptomatic Seizures ◽

Acute Symptomatic Seizures

Acute symptomatic epileptic seizures are one of the complications of hematopoietic stem cell transplantation. The etiological factors leading to the development of this complication differ from those in the general population, while the significance of each of them is different depending on the time after transplantation. We analyze the literature data on the role of drugs, metabolic disorders and infectious complications, as well as the structural pathology of the brain substance in the development of acute symptomatic seizures in patients with oncohematological pathology. We also consider the clinical features of symptomatic epileptic seizures and the possible prognostic significance of their development in patients who underwent hematopoietic stem cell transplantation.

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A STUDY OF ETIOLOGICAL AND CLINICAL PROFILE OF ACUTE SYMPTOMATIC SEIZURES IN ADULTS

10.36106/gjra/9304971 ◽

2020 ◽

pp. 1-3

Author(s):

Anbazhagan. G ◽

Vibuja E. ◽

Sarika N. Holla ◽

Chakradhar Arepalli

Keyword(s):

Neuronal Firing ◽

Panic Attacks ◽

Seizure Disorders ◽

Recent Recommendation ◽

Acute Symptomatic Seizure ◽

Symptomatic Seizures ◽

Idiopathic Epilepsies ◽

Acute Symptomatic Seizures ◽

International League ◽

Close Temporal Relationship

The word seizure is derived from Latin word “Sacire” meaning ‘to take possession of’. Seizure disorders are found Epilepsy can be broadly divided into idiopathic and symptomatic disorders. Idiopathic epilepsies are not associated with brain lesions or neurological abnormalities. They tend to be self limited and often respond well to antiepileptic therapy.An acute symptomatic seizure was defined in a recent recommendation from the International League Against Epilepsy (ILAE ) as a clinical seizure occurring in close temporal relationship with an acute central nervous system insult which may be metabolic, toxic, infectious or inflammatory. Seizures are common disorders found all over the that may require urgent attention and treatment to reverse world and are encountered frequently during medical potentially damaging causes. Such seizures are practice in variety of settings. Annually approximately considered to be an acute manifestation of the insult and 150,000 adults will present with a first seizure in the may not recur when the underlying cause has been United State1. India is home to about 10 million people removed or the acute phase has elapsed. The knowledge with epilepsy (prevalence of about 1%). An epileptic of the etiologic risk factors of acute symptomatic seizures seizure is an episode of neurologic dysfunction in which in third-world countries will invariably contribute to the abnormal neuronal firing is manifest clinically by changes effort aimed at preventing and managing medical conditions frequently complicated by seizures. The differential diagnosis of a single seizure includes psychogenic non-epileptic events, cardiac and neurogenic syncope, transient ischemic attacks, sleep disorders, and panic attacks.

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A study of etiology and characteristics of febrile convulsions and epilepsy among children

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20174738 ◽

2017 ◽

Vol 4 (6) ◽

pp. 2093

Author(s):

Habib G. Pathan ◽

Abdul Naseer Abdul Bari ◽

Prashant R. Kokiwar

Keyword(s):

Tertiary Care ◽

Epileptic Seizures ◽

Febrile Seizures ◽

Simple Type ◽

Upper Respiratory Tract ◽

Tertiary Care Centre ◽

Febrile Convulsions ◽

Male Preponderance ◽

Symptomatic Seizures ◽

Acute Symptomatic Seizures

Background: Globally in all parts of the world, epilepsy is the most common neurological disorder of chronic nature. Seizures among children are common and challenging for the pediatrician. The objective of this study was to study etiology and characteristics of febrile convulsions and epilepsy among childrenMethods: The present study was a prospective observational study conducted in a tertiary care centre among subjects who had seizures. Subjects were recruited from pediatric ward, consecutively hospitalization of pediatric patients, and of either sex who presented with history of seizures. The data included demographic details and history.Results: Total febrile seizures were 25.46% and overall incidence was around 2.57%. Preponderance of male constituting 62.65% over female 37.35% was observed. Most of the febrile seizures were simple type. Fever due to upper respiratory tract infection was commonest cause. It was not associated with any complications. Epileptic cases were 38.65% of total cases and overall incidence was 3.9%. In this group also, there was male preponderance. It increased with age. Commonest presentations of epileptic seizures were generalized in 67.46%. Most common cause of acute symptomatic seizures was viral encephalitis (28.34%). Numbers of deaths were more in acute symptomatic. Conclusions: As there were no morbidity and mortality with febrile seizures so it is possible to explain the benign nature of febrile seizures to their parents. Acute symptomatic seizures are to be identified and treated immediately.

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Second Paper: Deep Drawing and Free Forming Using a Water Hammer Technique

Proceedings of the Institution of Mechanical Engineers ◽

10.1243/pime_proc_1964_179_019_02 ◽

1964 ◽

Vol 179 (1) ◽

pp. 222-233 ◽

Cited By ~ 3

Author(s):

A. P. Vafiadakis ◽

W. Johnson ◽

I. S. Donaldson

Keyword(s):

Deep Drawing ◽

Time History ◽

Water Hammer ◽

High Rate ◽

Pressure Time ◽

Order Of Magnitude ◽

History Of ◽

Overall Efficiency ◽

Initial Movement ◽

Better Than

Earlier work on a water-hammer technique for high-rate forming of sheet metal has been extended to include work on deep drawing using lead plugs. A study of the pressure-time history of a deforming blank during its initial movement is reported. An assessment of the overall efficiency of the process has been made and is found to be about 50 per cent; this is an order of magnitude better than that found with comparable electro-hydraulic and explosive methods.

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Acute Symptomatic Seizures

The Neurologist ◽

10.1097/nrl.0b013e318251e6c3 ◽

2012 ◽

Vol 18 (3) ◽

pp. 109-119 ◽

Cited By ~ 26

Author(s):

Pedro Beleza

Keyword(s):

Symptomatic Seizures ◽

Acute Symptomatic Seizures

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Trends in prescribing patterns of antiepileptic drugs among older adult inpatients in a Brazilian tertiary center

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x-anp-2020-0012 ◽

2021 ◽

Vol 79 (1) ◽

pp. 22-29

Author(s):

Telma ASSIS ◽

Aroldo BACELLAR ◽

Luan CÔRTES ◽

Silas SANTANA ◽

Gersonita COSTA ◽

...

Keyword(s):

Risk Factors ◽

Antiepileptic Drugs ◽

Older Adult ◽

Late Onset ◽

Multivariate Logistic Regression Analysis ◽

Prescribing Patterns ◽

Convulsive Status Epilepticus ◽

Tertiary Center ◽

Symptomatic Seizures ◽

Acute Symptomatic Seizures

ABSTRACT Background: Data on prescribing patterns of antiepileptic drugs (AEDs) to older adult inpatients are limited. Objective: To assess changes in prescribing patterns of AEDs to older adult inpatients with late-onset epilepsy between 2009-2010 and 2015-2019, and to interpret any unexpected patterns over the 2015-2019 period. Methods: Patients aged ≥60 years with late-onset epilepsy from a tertiary center were selected. Demographic data, seizure characteristics and etiology, comorbidities, and comedications were analyzed, in addition to prescription regimens of inpatients taking AEDs to treat epilepsy. AED regimens were categorized into two groups: group 1 included appropriate AEDs (carbamazepine, oxcarbazepine, valproic acid, gabapentin, clobazam, lamotrigine, levetiracetam, topiramate, and lacosamide); and group 2 comprised suboptimal AEDs (phenytoin and phenobarbital). Multivariate logistic regression analysis was performed to identify risk factors for prescription of suboptimal AEDs. Results: 134 patients were included in the study (mean age: 77.2±9.6 years). A significant reduction in the prescription of suboptimal AEDs (from 73.3 to 51.5%; p<0.001) was found; however, phenytoin remained the most commonly prescribed AED to older adult inpatients. We also found an increase in the prescription of lamotrigine (from 5.5 to 33.6%) and levetiracetam (from 0 to 29.1%) over time. Convulsive status epilepticus (SE) and acute symptomatic seizures associated with remote and progressive etiologies were risk factors for the prescription of suboptimal AEDs. Conclusions: Phenytoin was the main suboptimal AED prescribed in our population, and convulsive SE and acute symptomatic seizures associated with some etiologies were independent risk factors for phenytoin prescription. These results suggest ongoing commitment to reducing the prescription of suboptimal AEDs, particularly phenytoin in Brazilian emergence rooms.

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