scholarly journals Primary bronchial myeloid sarcoma mimicking bronchogenic carcinoma: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wang Wang ◽  
Hesheng He ◽  
Xingwu Chen ◽  
Chenhong Zhang
Keyword(s):  
Bronchogenic Carcinoma ◽  
Mainland China ◽  
Immunohistochemical Analysis ◽  
Chest Ct ◽  
Myeloid Sarcoma ◽  
Case Presentation ◽  
Original Mass ◽  
Endobronchial Lesion ◽  
History Of ◽  
Chest Ct Scan

Abstract Background Myeloid sarcoma (MS) rarely involves the bronchus, and primary bronchial MS has almost never been reported in mainland China. Case presentation A 65-year-old female patient was admitted with a 3-month history of cough. She was initially diagnosed with bronchogenic carcinoma according to chest computed tomography (CT). However, after a biopsy was taken from the endobronchial lesion by bronchoscopy and further immunohistochemical analysis was performed, the diagnosis of MS was made. Because her bone marrow was normal and she had no history of haematologic diseases, we further considered the diagnosis of primary bronchial MS. The patient received chemotherapy with HAG regimens, and the original mass completely resolved, as confirmed by chest CT scan after 3 cycles of treatment. Meanwhile, no abnormalities were found on re-examination via bronchoscopy. Conclusions MS should be considered in the differential diagnosis in the presence of a suspicious pulmonary mass. Immunohistochemical analysis is necessary to confirm the diagnosis. Chemotherapy can lengthen the survival time for patients.

Myeloid Sarcoma of the Head and Neck Region

2013 ◽  
Vol 137 (11) ◽  
pp. 1560-1568 ◽  
Author(s):  
Jane Zhou ◽  
Diana Bell ◽  
L. Jeffrey Medeiros
Keyword(s):  
Head And Neck ◽  
Low Frequency ◽  
Neck Region ◽  
Immunohistochemical Analysis ◽  
Myeloid Sarcoma ◽  
Head And Neck Region ◽  
Bone Marrow Disease ◽  
Highly Sensitive ◽  
History Of ◽  
High Degree

Context.—Myeloid sarcoma of the head and neck region can pose diagnostic challenges because of the low frequency of myeloid sarcoma and the potential for tumors of almost any lineage to occur in the head and neck. Objective.—To study the clinicopathologic and immunohistochemical characteristics of myeloid sarcoma in the head and neck region and to review the differential diagnosis. Design.—We searched for cases of myeloid sarcoma involving the head and neck region for a 24-year period at our institution. The medical records and pathology slides were reviewed. Additional immunohistochemical stains were performed. Results.—We identified 17 patients, age 17 to 85 years. Most tumors involved the oral cavity. Myeloid sarcoma was the initial diagnosis in 9 patients (53%); the remaining 8 patients (47%) had a history of bone marrow disease. Immunohistochemical analysis using antibodies specific for lysozyme, CD43, and CD68 were highly sensitive for diagnosis but were not specific. By contrast, assessment for myeloperoxidase in this study was less sensitive but more specific. We also used antibodies specific for CD11c and CD33 in a subset of cases, and these reagents seem helpful as well. Conclusions.—The clinical presentation of myeloid sarcoma involving the head and neck, particularly the mouth, is often nonspecific, and a high degree of suspicion for the possibility of myeloid sarcoma is needed. Immunohistochemistry is very helpful for establishing the diagnosis.

scholarly journals Improvement with Infliximab of a Disseminated Sarcoidosis in a Patient with Crohn’s Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Nader Chebib ◽  
Fabrice Piégay ◽  
Julie Traclet ◽  
François Mion ◽  
Jean-François Mornex
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Ct Scan ◽  
Rare Case ◽  
Intestinal Tract ◽  
Chest Ct ◽  
Steroid Resistant ◽  
Abnormal Chest ◽  
History Of ◽  
Chest Ct Scan

Sarcoidosis and Crohn’s disease are systemic granulomatous disorders affecting the lung and the intestine, respectively, with variable involvement of other organs and are seldom associated. While anti-TNFαis a recognized treatment of Crohn’s disease, its usage is discussed in sarcoidosis. A 42-year-old man presented with an 11-year-long history of Crohn’s disease; upon discovery of an abnormal chest CT scan the diagnosis of multivisceral sarcoidosis was made and, later, a treatment with an anti-TNFαagent, infliximab, was started, because of worsening Crohn’s disease recurrences. CT scan demonstrated net regression of pulmonary opacities and hepatosplenic lesions. Pathologies obtained from the intestinal tract and the bronchi of the patient were, respectively, characteristic of Crohn’s disease and sarcoidosis leading to the diagnosis of both diseases. We report a rare case of steroid resistant Crohn’s disease associated with multivisceral sarcoidosis, treated successfully by an anti-TNFαagent, infliximab.

scholarly journals Mediastinum Lymph Node Hydatidosis.

2014 ◽  
pp. 28-28
Author(s):  
Yassine Ouadnouni ◽  
Marouane Lakranbi ◽  
Mohamed Smahi
Keyword(s):  
Lymph Node ◽  
Cystic Lesion ◽  
Chest Ct ◽  
Cystic Lesions ◽  
Surgical Exploration ◽  
Left Chest ◽  
History Of ◽  
One Year ◽  
Chest Ct Scan ◽  
Mediastinum Lymph Node

A 55 year old woman, presented to our hospital with a one year history of coughing and left chest pain. A chest CT-scan showed mediastinal, pleural and pulmonary cystic lesions evoking hydatidosis. Surgical exploration found a cystic lesion of the aorta-pulmonary window.

scholarly journals Retropharyngeal Abscess in an adult with Pneumonia during COVID-19 Outbreak in China

2020 ◽  
Author(s):  
Tianyu Wang ◽  
Haibin Liu ◽  
Caiquan Liang ◽  
Hang Zhang ◽  
Jianchun Liao ◽  
...  
Keyword(s):  
Foreign Body ◽  
Chest Ct ◽  
Retropharyngeal Abscess ◽  
Surgical Drainage ◽  
Case Presentation ◽  
Raising Awareness ◽  
Cervical Approach ◽  
Anterior Cervical Approach ◽  
Chest Ct Scan

Abstract Background: Retropharyngeal abscesses are rarely reported in adults and occur mostly in patients with immunocompromise or as a foreign body complication. Admittedly, the treatment of retropharyngeal abscesses frequently involves surgical drainage to achieve the best results. However, when retropharyngeal abscesses occurred in a highly suspected patient with COVID-19, the managements and treatments should be caution in order to prevent the spread of the virus. Case presentation: On Feb. 13, a 40-year-old male with retropharyngeal abscesses turned to our department complaining dyspnea and dysphagia. In addition, his chest CT scan shows a suspected COVID-19 infection, thus making out Multiple Disciplinary Team (MDT) determine to perform percutaneous drainage and catheterization through left anterior cervical approach under the guidance of B-ultrasound. Finally, the patient recovered and was discharged from the hospital on Feb. 27 after 14 days of isolation. There was no recurrence after half a year follow-up. Conclusions: By presenting this case, we aim at raising awareness of different surgical drainage methods and summarizing our experience in the management of retropharyngeal abscesses during the outbreak of COVID-19.

scholarly journals Elderly COVID-19 Pneumonic Patient with both Graded and Movable-weaning off Phenomenon or Yasser's Phenomena in a Surgical Severe Aortic Stenosis; at-home Dilemma Management

2021 ◽  
Vol 4 (5) ◽  
pp. 01-05
Author(s):  
Yasser Elsayed
Keyword(s):  
Risk Factors ◽  
Aortic Stenosis ◽  
Severe Aortic Stenosis ◽  
Chest Ct ◽  
Dynamic Changes ◽  
Case Presentation ◽  
Elderly Female ◽  
Patient Concerns ◽  
Chest Ct Scan

Rationale: Coronavirus disease is a leading remarkable critical pandemic global infection. Graded phenomenon or Yasser's phenomenon is a novel electrocardiographic phenomenon that changes the arrhythmia didactic. It is decisive progress in understanding arrhythmia. The phenomenon is a contemporary vigorous instructor for monitoring and follows up the arrhythmic patients. Movable-weaning off phenomenon or Yasser's phenomenon is another novel electrocardiographic phenomenon characterized by serial dynamic changes in all cases of either Wavy triple or double electrocardiographic signs (Yasser signs) of hypocalcemia. Movable-weaning off phenomenon is a guide for both Wavy triple and double an electrocardiographic. Severe symptomatic aortic stenosis has a bad outcome after the evolution of symptoms, and prompt operative intervention is advisable. Patient concerns: An elderly female COVID-19 pneumonic patient presented to physician outpatient clinic with bilateral peripheral pneumonia and both Graded and Movable-weaning off phenomenon or Yasser's phenomena in severe aortic stenosis. Diagnosis: Elderly COVID-19 pneumonia with both Graded and Movable-weaning off phenomenon or Yasser's phenomena. Interventions: Oxygenation, electrocardiography, chest CT scan, and echocardiography. Outcomes: Gradual dramatic clinical, electrocardiographic, and radiological improvement had happened. Lessons: It denotes the role of the anticoagulants, the antiplatelets, steroids, and antimicrobial therapy in the management of COVID-19 pneumonia with Graded and Movable-weaning off phenomenon or Yasser's phenomena in severe aortic stenosis. The presence of Graded and Movable-weaning off phenomenon or Yasser's phenomena, elderly, and pneumonia, in the case presentation, represent new complicated risk factors especially, with an associated severe sclerotic aortic stenosis. Short title: A case report article in cardiology, critical care, emergency medicine, and infectious diseases

scholarly journals Post traumatic painful shoulder – a delayed clinical feature of upper lobe lung cancer in a 74 year-old male. - case report -

2014 ◽  
Vol 20 (1) ◽  
pp. 40-43
Author(s):  
Arghir Oana-Cristina ◽  
Trenchea Mihaela ◽  
Iliescu Mădălina ◽  
Galie N. ◽  
Ciobotaru Camelia
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Chest Pain ◽  
Symptomatic Treatment ◽  
Chest Ct ◽  
Clinical Feature ◽  
Painful Shoulder ◽  
History Of ◽  
Post Traumatic ◽  
Chest Ct Scan

ABSTRACT A 74 year old Caucasian man, presents with a 6 week history of right sided chest pain including traumatic related painful right shoulder. Shoulder minor contusion was diagnosed and partial managed by symptomatic treatment associated to rehabilitation. The pain was initially eased with nonsteroidal anti-inflammatory drug (NSAID) use and finally changed worsening. He has evidence of moderate COPD on spirometry and has been commenced on inhalers. An invasive primitive adenocarcinoma lung cancer was confirmed by chest CT scan and lymphnode biopsy through mediastinoscopy

scholarly journals Simultaneous development of COVID-19 pneumonia and pulmonary metastasis in a known case of chondrosarcoma: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Afshin Rakhsha ◽  
Zahra Mahboubi-Fooladi ◽  
Anya Jafari
Keyword(s):  
Pulmonary Metastasis ◽  
Pulmonary Nodules ◽  
Simultaneous Presentation ◽  
Case Presentation ◽  
History Of ◽  
Polymerase Chain ◽  
Lung Ct ◽  
Chest Ct Scan ◽  
Interlobular Septal Thickening

Abstract Background The outbreak of coronavirus disease 2019 (COVID-19) started in December 2020, and is a global problem now. There are several sets of established data regarding computed tomography (CT) findings in COVID-19 pneumonia with many differential diagnoses. During the early days of the pandemic, there was little data regarding lung CT features of COVID-19 in a cancer patient. In this paper, we described a rare case of simultaneous presentation of COVID-19 with pulmonary metastasis. Case presentation A Persian patient with a history of chondrosarcoma presented to our clinic during the COVID-19 pandemic with a new-onset cough. He had experienced no recurrence during previous follow-up visits. Chest CT scan revealed numerous bilateral small peripheral and perilymphatic pulmonary nodules, unilateral ground-glass patch, and nodular interlobular septal thickening. Biopsy of the pulmonary nodules established pulmonary metastasis of chondrosarcoma origin, and pharyngeal reverse transcription polymerase chain reaction (RT-PCR) was positive for COVID-19. Conclusion Pulmonary metastasis should be considered as a differential diagnosis of COVID-19 features in cancer patients in the pandemic era.

scholarly journals COVID-19: Unilateral Involvement of Transplanted Lung, Sparing Contralateral Fibrotic Lung

2021 ◽  
Vol 16 (4) ◽  
Author(s):  
Mohammad Ali Kazemi ◽  
Nasrin Nikravangolsefid ◽  
Hamidreza Abtahi ◽  
Shahideh Amini ◽  
Hossein Ghanaati ◽  
...  
Keyword(s):  
Organ Transplant ◽  
Chest Ct ◽  
Transplant Recipients ◽  
Rt Pcr ◽  
Case Presentation ◽  
Pathologic Evaluation ◽  
Unilateral Involvement ◽  
Underlying Diseases ◽  
Chest Ct Scan

Introduction: Organ transplant recipients might be more likely to develop COVID-19, as they receive long-term immunosuppressives and have comorbidities. Case Presentation: Herein, we reported the case of a 32-year-old man with unilateral lung transplantation due to unclassifiable lung fibrosis on pathologic evaluation who presented with cough, fever, and headache. After evaluation with RT-PCR test and chest CT scan, COVID-19 in the previously transplanted lung was diagnosed. However, the other non-transplanted fibrotic lung was not involved. Conclusions: Lack of COVID-19 involvement in the fibrotic lung tissue in our case without any other risk factors might be related to the fact that the lung with underlying diseases was less susceptible to COVID-19 as unhealthy lungs have lower ACE2 receptors, or it might be related to genetic differences between the donor and recipient.

scholarly journals The First Presentation of Pediatric COVID-19 With Diabetic Ketoacidosis: A Unique Case Report

2020 ◽  
Vol 8 (3) ◽  
pp. 131-133 ◽  
Author(s):  
Shahin Jafarpoor ◽  
Masoumeh Abedini ◽  
Fatemeh Eghbal ◽  
Amin Saburi
Keyword(s):  
Diabetic Ketoacidosis ◽  
Nasal Swab ◽  
Chest Ct ◽  
Rt Pcr ◽  
Unique Case ◽  
Case Presentation ◽  
The World ◽  
Underlying Diseases ◽  
Chest Ct Scan ◽  
Pcr Test

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or COVID-19, is a pandemic infectious disease involved all over the world. Its mortality, especially in cases with additional co-morbidities, is so high that is has attracted the attention of the world. Diabetes mellitus is known as one of its risk factors for mortality. Case Presentation: A unique case of pediatrics COVID-19 who presented with diabetic ketoacidosis (DKA) is reported in this manuscript as the first presentation. He presented with abdominal pain, nausea, and vomiting. RT-PCR test for COVID-19 via nasal swab was performed, and a positive diagnosis was obtained. Chest CT scan confirmed the diagnosis with multifocal bilateral patchy consolidation. Case was discharged after usual treatment of COVID-19. Conclusion: In pediatrics, this disease can be subtle and have a confusion presentation, but it should be controlled to avoid spread of the disease. During epidemic status, suspicious cases specially children with nonspecific symptoms and other underlying diseases should be considered as at risk or potentially asymptomatic COVID-19 cases.

scholarly journals Lung Involvement in Gaucher Disease

2020 ◽  
Author(s):  
Mahnaz PejmanSani ◽  
Keivan GohariMoghadam ◽  
Mahbube Ebrahimpur
Keyword(s):  
Gaucher Disease ◽  
Autosomal Recessive ◽  
Pulmonary Involvement ◽  
Severe Form ◽  
Lysosomal Storage ◽  
Case Presentation ◽  
Progressive Dyspnea ◽  
History Of ◽  
Chest Ct Scan ◽  
Restrictive Pattern

Introduction: Gaucher Disease is an autosomal recessive lysosomal storage disease. Pulmonary involvement in Gaucher Disease is rare and often seen in the severe form of the disease with the worst outcome. Case Presentation: A 30-year-old man and known case of Gaucher Disease presented to our clinic with history of progressive dyspnea since 8 months ago. Pulmonary function test showed restrictive pattern. Chest CT scan revealed diffuse bilateral interlobular septal thickening and small interstitial nodules with ground glass opacities in lower lobes. Conclusion: Patients with Gaucher Disease that present with progressive dyspnea may have a manifestation of interstitial or alveolar lung disease.

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