scholarly journals Combined prognostic nutritional index ratio and serum amylase level during the early postoperative period predicts pancreatic fistula following pancreaticoduodenectomy

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Teruhisa Sakamoto ◽  
Takuki Yagyu ◽  
Ei Uchinaka ◽  
Masaki Morimoto ◽  
Takehiko Hanaki ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Postoperative Period ◽  
Serum Amylase ◽  
Prognostic Nutritional Index ◽  
Early Postoperative Period ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Nutritional Index ◽  
Index Ratio

scholarly journals To Study the Biochemical Markers for the Prediction of Fistula Formation after Pancreatic Resection Surgery in the Post Operative Period

2021 ◽  
Vol 3 (2) ◽  
pp. 33-39
Author(s):  
SA Mir ◽  
S. Akhter ◽  
S. S. Ahmad ◽  
S. H. Altaf ◽  
J. Ahmad ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Pancreatic Resection ◽  
Serum Amylase ◽  
Postoperative Pancreatic Fistula ◽  
Fistula Formation ◽  
Amylase Level ◽  
Medical Procedure ◽  
Serum Amylase Level ◽  
Post Operation ◽  
Laboratory Biomarkers

Background: To study and assess the potential laboratory biomarkers for foreseeing postoperative pancreatic fistula (POPF) after pancreatic resection medical procedures. Subjects and Methods: 64 patients were studied from Jan 2008 to Dec 2018. All patients undergoing Pancreatic resection surgeries like Pancreaticoduodenectomy (PD), distal Pancreatectomy (DP) for tumors of the periampullary region, Pancreatic body or chronic pancreatitis Clinical data of the patients, surgical approach, pancreatic parenchymal tissue consistency, histopathology of the specimen, white blood cell count and blood amylase levels tube Drain fluid amylase were recorded and analyzed. Correlations between these parameters and postoperative pancreatic fistula (POPF) were assessed. Results : 22 out of the 64 (34.37%) patients developed POPF. The fistula was graded according to the ISPG classification. It was Grade An of every 10 (45.45%) patients, grade B in 8 (36.36%), and grade C in 4 (18.18%),.On univariate and multivariate strategic relapse investigations, higher amylase levels in the stomach waste liquid on a postoperative day (POD)1 and higher serum amylase levels on POD4 indicated a critical relationship with fistula arrangement in the post-operation period (POPF) (P < 0.05). On ROC (recipient working trademark bend) examination, amylase cut-off degree of 2270.67 U/L in the stomach waste liquid was related with a 76.6% affectability and 82% particularity [area under the bend (AUC): 0.844; P = 0.009]. A cut-off serum amylase level of 53.2 U/L was related with a 74.6% affectability and 72.9% explicitness (AUC: 0.784; P = 0.05). Conclusion: Post-operative channel liquid amylase levels on day 1 and serum amylase level on day 4 speak to interesting biomarkers related to POPF improvement after the pancreatic medical procedure.

scholarly journals A clinical investigation of the association between perioperative oral management and prognostic nutritional index in patients with digestive and urinary cancers

2020 ◽  
Vol 27 (5) ◽  
Author(s):  
H. Otagiri ◽  
S. Yamada ◽  
M. Hashidume ◽  
A. Sakurai ◽  
M. Morioka ◽  
...  
Keyword(s):  
Postoperative Period ◽  
Medical Records ◽  
Clinical Investigation ◽  
Oral Intake ◽  
Prognostic Nutritional Index ◽  
Early Postoperative Period ◽  
Patients With Cancer ◽  
Positive Effects ◽  
Management Interventions ◽  
Nutritional Index

Background The prognostic nutritional index (pni) is a simple metric calculated using serum albumin and the peripheral lymphocyte count. It was reported that a low pni score is significantly associated with major postoperative complications and poor prognosis. The purpose of the present study was to investigate the effects of perioperative oral management (pom) on the perioperative pni profiles of patients with digestive system or urinary cancers. Study Design The medical records of 181 patients with cancer who underwent surgery and for whom a pni could be calculated were retrospectively reviewed. Results The intervention rate with pom was 34.8%. The median preoperative pni score was 48.25 in all patients with a pom intervention [25% to 75% interquartile range (iqr): 44.38–54.13] and 47.25 in those without an intervention (iqr: 42.0–53.5). Compared with patients not receiving pom, those who received pom had significantly higher pni scores from the early postoperative period (p < 0.05). Notably, of patients who could resume oral intake within 3 days after surgery, those who received pom intervention, compared with those who did not, had significantly higher pni scores from the early postoperative period (p < 0.05). Conclusions Perioperative oral management interventions might have positive effects on the postoperative pni scores of patients with cancer.

The Combination of Pancreas Texture and Postoperative Serum Amylase in Predicting Pancreatic Fistula Risk

2018 ◽  
Vol 84 (6) ◽  
pp. 889-896 ◽  
Author(s):  
Crystal B. Chen ◽  
Neal S. McCall ◽  
Michael J. Pucci ◽  
Benjamin Leiby ◽  
Nooreen Dabbish ◽  
...  
Keyword(s):  
Pancreatic Fistula ◽  
Serum Amylase ◽  
Characteristic Curve ◽  
Multivariable Analysis ◽  
Threshold Value ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Soft Pancreas ◽  
Postoperative Serum ◽  
The Relationship

Postoperative pancreatic fistula (PF) remains one of the most significant complications after pancreaticoduodenectomy (PD). Recently, studies have suggested that post-PD serum hyper-amylasemia (HA) may be a risk factor. In this study, we evaluate the relationship of pancreas texture and post-operative serum amylase levels in determining PF risk. This retrospective cohort study evaluated all patients who underwent PD at Thomas Jefferson University from 2009 to 2014. The highest postoperative serum amylase level from postoperative day (POD) 0 to POD 5 was obtained. Chi-square analyses and odds ratio (OR) evaluated the relationship between pancreas texture, serum amylase level, and the development of PF. Data from 524 consecutive patients were analyzed. Serum amylase threshold value of 165 IU/L yielded greatest accuracy from the receiver operating characteristic curve analysis (Sensitivity, 0.70; specificity, 0.72). Grade B or C PF were more common among HA patients (20 vs 3%; P < 0.001). HA was associated with increased rates of PD-associated complications. On multivariable analysis, early postoperative serum HA was more predictive of PF risk (OR, 4.87; P < 0.001) than either pancreatic duct size ≤3 mm (OR, 2.97; P = 0.01) or pancreas texture (OR,1.87; P = 0.05). Conclusion: The presence of HA on POD 0 or POD 1 is more predictive than soft pancreas texture or small pancreas duct size alone.

scholarly journals Arthralgia and Osteolytic Lesions Associated with Traumatic Pancreatitis in a 10-Year-Old Girl

2009 ◽  
Vol 2009 ◽  
pp. 1-3
Author(s):  
Masayuki Obatake ◽  
Yusuke Yamane ◽  
Takayuki Tokunaga ◽  
Yasuaki Taura ◽  
Yukio Inamura ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Joint Pain ◽  
Serum Amylase ◽  
Knee Joints ◽  
Pancreatic Pseudocysts ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Osteolytic Lesions ◽  
Pseudocyst Drainage ◽  
Traumatic Pancreatitis

A case of traumatic pancreatitis with subsequent joint pain and osteolytic lesions is presented. A 10-year-old girl was admitted to our hospital with abdominal pain caused by blunt epigastric injury. She was diagnosed with traumatic pancreatitis, and multiple pancreatic pseudocysts subsequently developed. Two weeks after admission, she complained of joint pain, and MR revealed osteolytic lesions of both knee joints. On the 58th day, endoscopic transgastric pseudocyst drainage was performed. Joint pain and osteolytic lesions resolved rapidly, in parallel with the decrease in serum amylase level and pseudocyst size.

scholarly journals Abdominal pain and a raised amylase? It’s not always pancreatitis…

2013 ◽  
Vol 12 (3) ◽  
pp. 163-165
Author(s):  
IO Oluwatowoju ◽  
◽  
EO Abu ◽  
G Lawson ◽  
◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Serum Amylase ◽  
Epigastric Pain ◽  
Elevated Serum ◽  
High Serum ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption ◽  
History Of

We report the case of a 72 year old man with a history of COPD and heavy alcohol consumption who was initially diagnosed with acute pancreatitis based on a presentation with epigastric pain and elevated serum amylase. Review of his notes revealed several previous similar admissions and extensive normal investigations apart from persistently elevated amylase. Further analysis showed evidence of macroamylasaemia which accounted for the apparently high serum amylase level.

scholarly journals Predictive value of serum amylase level in outcome of multiple trauma patients

2016 ◽  
Vol 4 (2) ◽  
pp. 115-121
Author(s):  
Arezu Nejabatian ◽  
Farzad Rahmani ◽  
Rozbeh Rajaei Ghafori ◽  
Samad Shams Vahdati ◽  
Parizad Varghayi ◽  
...  
Keyword(s):  
Multiple Trauma ◽  
Predictive Value ◽  
Serum Amylase ◽  
Amylase Level ◽  
Trauma Patients ◽  
Serum Amylase Level ◽  
Multiple Trauma Patients

scholarly journals AN ANALYSIS OF SERUM AMYLASE LEVEL IN CHOLELITHIASIS PATIENTS

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Anita Verma ◽  
Prerna Harsh
Keyword(s):  
Serum Amylase ◽  
Health Care Systems ◽  
Gallstone Disease ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Case Group ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Medical College ◽  
Care Systems

Background: Gallstone disease (GSD) is one of the most common gastrointestinal diseases. Gallstones represent a significant burden for health care systems worldwide and are one of the most common disorders presenting to emergency room. Methods: Hospital based case control study conducted at Department of Biochemistry with close collaboration of Department of General Surgery, S. P. Medical College and associated group of PBM Hospital, Bikaner, Rajasthan. Results: The insignificant serum amylase level difference in case group (47.80± 21.24) as compares to control group (45.97± 16.38). Conclusion: In this study comparison of amylase between case and controls group showed that the levels of amylase in cholelithiasis patients were higher than that of the control group, but there was no significant variation in amylase. Keywords: Amylase, cholelithiasis, Gallstone disease (GSD).

Sign in / Sign up

Export Citation Format

Share Document