scholarly journals Drug use and antiretroviral therapy (ART) interactions: a qualitative study to explore the knowledge, beliefs, adherence, and quality of life of people living with HIV taking ART and illicit drugs

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
María José Fuster-RuizdeApodaca ◽  
Vanessa Castro-Granell ◽  
Ana Laguía ◽  
Ángeles Jaén ◽  
Santiago Cenoz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Drug Use ◽  
Qualitative Study ◽  
Illicit Drugs ◽  
People Living With Hiv ◽  
Living With Hiv

scholarly journals Gender Differences in Health Related Quality of Life among People Living with HIV on Highly Active Antiretroviral Therapy in Mekelle Town, Northern Ethiopia

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Amanuel Tesfay ◽  
Abebe Gebremariam ◽  
Mulusew Gerbaba ◽  
Hailay Abrha
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Health Related Quality ◽  
Highly Active ◽  
Related Quality ◽  
Health Related ◽  
Living With Hiv

Background. Health related quality of life (HRQOL) is an important outcome measure for highly active antiretroviral treatment program. In Ethiopia, studies revealed that there are improved qualities of life among adults living with the viruses taking antiretroviral therapy but there is no explicit data showing gender differences in health related quality of life.Aim. To assess gender differences in HRQOL and its associated factors among people living with HIV and on highly active antiretroviral therapy in public health institutions of Mekelle town, Northern Ethiopia.Methods. A comparative cross-sectional study was conducted among 494 adult people living with HIV taking ART services. Quality of life was measured using WHOQOL-HIV BREF.Result. There was a statistically significant gender difference (P<0.05) in HRQOL among PLHIV on HAART. Females had low score in all HRQOL domains. High perceived stigma was strongly associated with poor psychological quality of domain among both female and male groups with[AOR=2.89(1.69,4.96)]and[AOR=2.5(1.4,4.4)], respectively.Conclusion. There was statistically significant gender difference in all quality of life domains. Public health interventions to improve HRQOL of PLHIV should take in to account the physical, psychological, social, environmental, and spiritual health of PLHIV during treatment, care, and support.

scholarly journals Quality of Life People Living with HIV-AIDS (PLWHA) with Antiretroviral therapy in Cendana Clinic Ngudi Waluyo Wlingi Hospital

2015 ◽  
Vol 2 (1) ◽  
pp. 006-014
Author(s):  
Erni Setiyorini
Keyword(s):  
Quality Of Life ◽  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Environment Problem ◽  
Immunodeficiency Virus ◽  
Long Time ◽  
Living With Hiv ◽  
Hiv Aids

Human Immunodeficiency Virus (HIV)is desease with high mortality and everyone have chancegot HIV. At Blitar HIV/AIDS prevalence increase since 2010. The incubation of HIV need long time tobecome AIDS. At this period PLWHA faced with physic, physichologic, sosial, environment problem andimpact to their quality of life. The purpose of this study was to describe quality of life PLWHA at physic,physichologic, sosial, environment dimension. Method: Research design was descriptive. Population ofthis study is PLWHA who receiving ARV at Cendana Clinic Ngudi Waluyo Wlingi Hospital. Samples 42respondent by using convenient sampling. Data collected at September 1st– 30, 2013 by questionaire.Result of this study in physic dimension much of them at good 16 peoples (38,1%), enough and less, eachof them 13 peoples (31%). Physhicology dimension at good and enough, each of them 20 peoples(47,6%) then at less 2 peoples (4,8%). Sosial dimension enough 25 peoples (59,5%), good 15 peoples(35,7%) and less 2 peoples (4,8%). Environment dimension enough 16 peoples (38,1%), good 15peoples (35,7%) dan kurang 11 orang (26,2%). It is suggested for nurse to implementation nursing careplan to PLWHA suitable with their quality of life dimension and enhance support to their sosial activity.

scholarly journals Quality of life domains relevant to people living with HIV and AIDS who are on antiretroviral therapy in Swaziland

Curationis ◽  
2012 ◽  
Vol 35 (1) ◽  
Author(s):  
Theresa T. Ntshakala ◽  
Thandisizwe R. Mavundla ◽  
Bethabile L. Dolamo
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Hiv And Aids ◽  
Cognitive Domain ◽  
Second Phase ◽  
People Living With Hiv ◽  
Contextual Design ◽  
Context Specific ◽  
Living With Hiv

Quality of life (QOL) domains that are context specific to people living with HIV and AIDS (PLWHA) who are on antiretroviral therapy (ART) in Swaziland are unknown. This presents a problem when research has to be conducted on QOL of PLWHA who are on ART. As a result, this study was conducted to identify, validate and describe domains necessary to assess QOL of PLWHA, who are on ART in Swaziland. A qualitative, explorative, descriptive, and contextual design was used for this study. The first phase dealt with a review of fifty existing QOL definitions and the identification of the common domains amongst them. Findings from this review revealed that the most common domains of QOL are the physiological, psychological, spiritual and socio-economic domains. The second phase was the validation of the above common domains identified from the examined QOL definitions to make them context specific to PLWHA who are on ART in Swaziland. A workshop was used to validate the domains with expert nurses involved in the care of PLWHA in Swaziland. The experts in ART care were trained on ART and had more than a year’s experience of working with PLWHA who are on ART. The validation process revealed that the essential context specific domains to consider when assessing QOL of PLWHA who are on ART are, (1) physiological domain, (2) psychological domain, (3) spiritual domain, (4) socio-economic domain, (5) cognitive domain, and (6) environmental domain. The process of validation of the domains was important as two extra domains were revealed, which were not initially recognised by the researcher during literature review.

scholarly journals Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0260334
Author(s):  
Vanessa Castro-Granell ◽  
Noé Garin ◽  
Ángeles Jaén ◽  
Santiago Cenoz ◽  
María José Galindo ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Drug Use ◽  
Illicit Drugs ◽  
Significant Proportion ◽  
People Living With Hiv ◽  
Close Monitoring ◽  
Cross Sectional Survey ◽  
Increased Risk ◽  
Living With Hiv ◽  
The Impact

Drug use implies important challenges related to HIV management, particularly due to an increased risk of potential interactions between antiretroviral therapy (ART) and illicit drugs (pDDIs). This study analyses the prevalence and severity of pDDIs among people living with HIV (PLHIV). It also explores their awareness of pDDIs and their beliefs about the toxicity that they may cause, as well as the impact of pDDIs on selected health variables. We conducted an on-line cross-sectional survey across 33 Spanish hospitals and NGOs to collect demographics and clinical data. pDDIs were checked against the Interaction Checker developed by Liverpool University. The sample of the present study was composed of 694 PLHIV who used illicit drugs. They represented 49.5% of the 1,401 PLHIV that participated in the survey. After excluding 38 participants due to lack of information on their ART or illicit drug use, 335 (51.1%) participants consuming drugs presented with some potentially significant pDDIs between their ART and illicit drugs, with a mean of 2.1±1.7 (1–10) pDDIs per patient. The drugs most frequently involved in pDDIs were cocaine, cannabis, MDMA and nitrates ("poppers"). The prevalence of pDDIs across ART regimens was: protease inhibitors (41.7%); integrase inhibitor-boosted regimens (32.1%), and non-nucleoside reverse transcriptase inhibitors (26.3%). An awareness of pDDIs and beliefs about their potential toxicity correlated positively with intentional non-adherence (p<0.0001). Participants with pDDIs exhibited a higher prevalence of intentional non-adherence (2.19±1.04 vs. 1.93±0.94; p = 0.001). The presence of pDDIs was not associated with poorer results in the clinical variables analysed. A significant proportion of PLHIV who use drugs experience pDDIs, thereby requiring close monitoring. pDDIs should be considered in the clinical management of HIV patients. Adequate information about pDDIs and indicators about how to manage ART when PLHIV use drugs could improve ART non-adherence.

scholarly journals Quality of life of people living with HIV, preliminary results from IANUA (Investigation on Antiretroviral Therapy) study

2014 ◽  
Vol 17 ◽  
pp. 19581 ◽  
Author(s):  
Alberto Venturini ◽  
Barbara Giannini ◽  
Marcello Montefiori ◽  
Antonio Di Biagio ◽  
Giovanni Mazzarello ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
People Living With Hiv ◽  
Preliminary Results ◽  
Living With Hiv

scholarly journals A patient-centred approach to deprescribing antiretroviral therapy in people living with HIV

2020 ◽  
Vol 75 (12) ◽  
pp. 3425-3432
Author(s):  
Giovanni Guaraldi ◽  
Jovana Milic ◽  
Simone Marcotullio ◽  
Cristina Mussini
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Therapy ◽  
Drug Interactions ◽  
Precision Medicine ◽  
Lived Experience ◽  
People Living With Hiv ◽  
Drug Regimens ◽  
Long Acting ◽  
Living With Hiv

Abstract Only a few studies have explored the benefit of deprescribing in people living with HIV (PLWH), focusing on the discontinuation of non-antiretrovirals (non-ARVs) used for HIV-associated comorbidities (co-medications), or the management of drug–drug interactions (DDIs) between ARVs or between ARVs and co-medications. The availability of modern single-tablet regimens, two-drug regimens and long-acting therapy opens a discussion regarding ARV deprescribing strategies. The objective of this article is to discuss ARV deprescribing strategies in the context of medication-related burden and patients’ lived experience with medicine (PLEM) and to suggest indications for whom, when, how and why to consider these ARV options in PLWH. A PLEM construct helps to better interpret these strategies and provides a patient-centred precision-medicine approach. There are several safe and virologically effective ARV deprescribing strategies, but the ultimate benefits of these interventions still need to be further explored in terms of the overall health and quality of life of patients.

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