scholarly journals A comparison between survival from cancer before and after a physical traumatic injury: physical trauma before cancer is associated with decreased survival

Author(s):  
Douglas L. Delahanty ◽  
Robert Marley ◽  
Andrew Fenton ◽  
Ann Salvator ◽  
Christina Woofter ◽  
...  
Palaios ◽  
2020 ◽  
Vol 35 (4) ◽  
pp. 201-214 ◽  
Author(s):  
BETHANIA C.T. SIVIERO ◽  
ELIZABETH REGA ◽  
WILLIAM K. HAYES ◽  
ALLEN M. COOPER ◽  
LEONARD R. BRAND ◽  
...  

ABSTRACT This study presents evidence of pre-mortem traumatic injury and its sequalae on multiple Edmontosaurus annectens skeletal elements recovered from a largely monodominant Cretaceous (Maastrichtian) bonebed. The sample consists of 3013 specimens excavated and prepared from two quarries, of which 96 elements manifest one or more macroscopic bone abnormalities and 55 specimens display pathology attributable to physical trauma. Evidence of traumatic pathology is strongly associated (P < .05) with body region, occurring disproportionately in the caudal vertebrae. Pre-mortem fractures with subsequent bone remodeling and hypertrophic ossification of caudal neural spines are present principally in the middle and mid-distal regions of the tail, while fractures of the vertebral centra are present primarily in the distal tail region. Other skeletal regions, such as chevrons, phalanges of the manus and ribs display unambiguous evidence of healed trauma, but with less frequency than the tail. These findings, in combination with current understanding of hadrosaurian tail biomechanics, indicate that intervertebral flexibility within the middle and mid-distal region of the tail likely rendered these caudal vertebrae more susceptible to the deleterious effects of repeated mechanical stress and subsequent trauma, potentially accompanying running locomotion and other high-impact herd interactions. Healed fractures within the region are also suggestive of accumulated injuries due to a combination of tail usage in defense and possibly accidental bumping/trampling associated with gregarious behavior.


2010 ◽  
Vol 112 (4) ◽  
pp. 832-839 ◽  
Author(s):  
Satoru Osuka ◽  
Akira Matsushita ◽  
Tetsuya Yamamoto ◽  
Kousaku Saotome ◽  
Tomonori Isobe ◽  
...  

Object Ventriculomegaly is a common imaging finding in many types of conditions. It is difficult to determine whether it is related to true hydrocephalus or to an atrophic process by using only imaging procedures such as MR imaging after traumatic injury, stroke, or infectious disease. Diffusion tensor (DT) imaging can distinguish the compression characteristics of white matter, indicating that increased diffusion anisotropy may be related to white matter compression. In this preliminary study, the authors compared the DT imaging findings of ventriculomegaly with those of chronic hydrocephalus or atrophy to clarify the potential of diffusion anisotropy in the identification of hydrocephalus. Methods Ten patients with chronic hydrocephalus, 8 patients with atrophy (defined by conventional devices and surgical outcome), and 14 healthy volunteers underwent DT imaging. Images were acquired before and after shunting or once in cases without shunting. The fractional anisotropy (FA) values at many points around the lateral ventricle were evaluated. Results The FA patterns around the lateral ventricle in the chronic hydrocephalus and atrophy groups were different. Especially in the caudate nucleus, FA was increased in the chronic hydrocephalus group compared with the atrophy group. Furthermore, the FA values returned to normal levels after shunt placement. Conclusions Assessment of the FA value of the caudate nucleus may be an important, less invasive method for distinguishing true hydrocephalus from ventriculomegaly. Further research in a large number of patients is needed to verify the diagnostic ability of this method.


2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 47-47
Author(s):  
Vlad Covrig ◽  
◽  
Cristian Budacu ◽  
Beatrice Ioan ◽  
◽  
...  

"The face is the feature which best distinguishes a person, the shape of it being influenced by the bone-structure of the skull. Facial trauma, known as maxillofacial trauma, is any physical trauma to the face that can involve soft and hard tissue having the potential to cause disfigurement. The last resort solution after major facial trauma, when conventional reconstruction techniques have failed is now represented by face transplant. The aim of this paper is to underline the life quality and psychological implication of patients that were face transplanted. Our material and method involved studying the most relevant medical literature for this issue and also using our personal experience of patient with face cancer that underwent radical oncological surgery followed by reconstruction. Based on these data we can conclude that face transplantation appears to decrease depression and to improve patient’s quality of life and societal reintegration. Also, in our opinion a very important factor involving the success of face transplantation is represented by the psychological outcomes of the patients, their follow up for a minimum 6 months period with regular psychological counselling sessions being very important. Furthermore, there is a critical need for modification of existing rating scales to allow effective assessment of face transplant candidates before and after transplantation. "


Reumatismo ◽  
2015 ◽  
Vol 67 (2) ◽  
Author(s):  
J. N. Ablin ◽  
V. Aloush ◽  
A. Brill ◽  
M. Berman ◽  
M. Barzilai ◽  
...  

The fibromyalgia syndrome (FMS) is considered to result from the exposure of a genetically susceptible individual to various triggers, such as physical trauma, stress, viral infections etc. A possible role of vaccination in FMS etiology has been suspected. Our objective was to evaluate the efficacy and safety of influenza vaccination in FMS patients. Nineteen FMS patients underwent physical and dolorimetric examinations and answered the fibromyalgia impact questionnaire (FIQ), the widespread pain index (WPI) checklist and the symptoms severity scale (SSS), which are part of the 2010 diagnostic criteria. Thirty-eight healthy subjects were recruited as controls. All participants were vaccinated with the inactivated split virion influenza vaccine. Serum was collected for antibody titration. Six weeks after vaccination, sera were tested by hemagglutination (HI) against A/California (H1N1), A/Perth (H3N2) and B/Brisbane. Humoral response was defined as either a fourfold or greater increase in titer, or an increase from a non-protective baseline level of <1/40 to a level of 1/40. No severe vaccination reactions were observed. No significant change was observed between WPI, SSS and FIQ values before and after vaccination, indicating no worsening of FMS symptoms. Vaccine immunogenicity: Six weeks after vaccination, FMS patients showed a significant increase in geometric mean titers of HI antibody. The rates of sero-protection increased from 22.9% for H1N1 to 89.5% post-vaccination. A significant increase in HI antibody titers was also demonstrated among healthy controls. Influenza vaccination was both safe and effective in FMS patients. In view of these results, FMS patients should be encouraged to undergo influenza vaccination according to the standard WHO recommendations.


2012 ◽  
Vol 11 (1) ◽  
pp. 7
Author(s):  
Hanna Silvia Debora ◽  
Nada Ismah ◽  
Benny Mulyono Soegiharto

Treatment with a fixed orthodontic aims to improve malocclusion and enhance the aesthetic. Traumatic injury to themucosa of the mouth is one of the risks that often occur and can be addressed among others by using mouthwashthat contains hyaluronic acid. This study aimed to determine the effectiveness of 0.1% hyaluronic acid on woundhealing caused by trauma of fixed rthodontic appliance in terms of size wound, redness and pain. Twenty twopatients who had a traumatic injury caused by fixed appliance on buccal or labial mucosa were divided into 2groups: K1, was instructed to rinse 10 ml solution containing 0.1% hyaluronic acid for 2 minutes after brushingteeth, 2 times a day for 4 days; K2, used the K1’s instruction but using a placebo solution. Examination of size areused caliper and reddish wounds are used index measuring wound redness performed before and after treatment,and pain measurement used questionnaires. Based on the statistical analysis of t-test, the percentage of size changes and redness traumatic injury were more significant in K1 than in K2 (p<0.05). While the pain of traumatic changesin K1 than in K2 were not significant (p>0.05). The use of mouthwash containing 0.1% hyaluronic acid wasconcluded proved effective to accelerate the wound healing process, but does not prove effective reducing paincaused by traumatic injury due to fixed orthodontic appliance.


2017 ◽  
Vol 1 ◽  
pp. 205970021770477
Author(s):  
Lynne R Ferrari ◽  
Michael J O’Brien ◽  
Alex M Taylor ◽  
Travis H Matheney ◽  
David Zurakowski ◽  
...  

Background Each year in the United States approximately three million individuals sustain sport or recreation-related concussion which may occur in the setting of orthopedic trauma requiring surgical intervention under general anesthesia. The effects of surgery and general anesthesia on brain recovery are currently unknown. The objective of this study was to determine the prevalence of recent sport concussion, recognized or not, in a preoperative, pediatric, surgical population. Methods The study involved administering a questionnaire to all eligible, consented patients in one of the following settings: Preoperative Clinic, Day Surgery Unit, Trauma Clinic, or inpatient floor. The questionnaire was designed to determine the occurrence and symptoms of a concussion. This study was conducted at an urban 395-bed comprehensive center for pediatric health, between May 2014 and April 2015. Inclusion criteria for study were age 5–21 years, presentation for surgical repair of orthopedic traumatic injury or nasal fracture, and precipitating injurious event occurring within four weeks of surgery. Results The prevalence of concussion in the setting of orthopedic trauma, either known or unknown at the time of presentation for surgery was 6%. The interval between surgery and injury was between three and 13 days. Prior education for recognition of concussion was present in 66% of patients. Conclusions The impact of surgery with general anesthesia in pediatric patients with a recent concussion is unknown. No changes in post-op disposition were noted in this patient population. However, our findings support the need to measure neurocognitive function before and after administration of operative procedures in a larger population with a recent concussion compared with controls.


Author(s):  
Duane R. Bidwell

Psychosocial interventions and systematic theology are primary resources for chaplains and congregational pastors who care for victims of physical trauma. Yet these resources may not be adequate to address the spiritual impacts of trauma. This article proposes a preliminary “pneumatraumatology,” drawing on early Christian asceticism and Buddhist mysticism to describe one way of understanding the spiritual impacts of traumatic injury. It also suggests possible responses to these impacts informed by narrative/constructionist perspectives and Brueggemann's understanding of the dimensions of spiritual transformation in the Hebrew Bible.


2020 ◽  
Author(s):  
Xin Wang ◽  
Yue-ting Kang ◽  
Xin-yi Li ◽  
Wei Liu ◽  
Zhong-liang Liu ◽  
...  

Abstract Background: Neurogenic sexual dysfunction (NSD) is a common problem in patients after spinal and pelvic trauma. New treatment is needed beyond medicine or psychological therapies. This study probes the potential for using repetitive transcranial magnetic stimulation (rTMS) for NSD rehabilitation, the insights of which can inform further research.Methods: In a 24-year-old man who fell from six floor building, with multiple spinal and pelvic injuries, we used rTMS to treat his subsequent NSD. The therapy lasted for 3 months. Motor and sensory conductivities, as well as sexual function, were evaluated before and after the treatment.Results: The rTMS regimen produced satisfactory improvement on patient’s nerve conductivities and sexual activity. Improvements in sexual function were confirmed at 1-year follow-up. Conclusions: rTMS delivered a positive treatment to this patient with NSD. Potential mechanisms by which rTMS regulate sexual function need to be further investigated.


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