scholarly journals Impact of the Umoyo mother-infant pair model on HIV-positive mothers’ social support, perceived stigma and 12-month retention of their HIV-exposed infants in PMTCT care: evidence from a cluster randomized controlled trial in Zambia

Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Sydney Chauwa Phiri ◽  
Sandra Mudhune ◽  
Margaret L. Prust ◽  
Prudence Haimbe ◽  
Hilda Shakwelele ◽  
...  
Keyword(s):  
Social Support ◽  
Controlled Trial ◽  
Hiv Positive ◽  
Perceived Stigma ◽  
Randomized Controlled ◽  
Pair Model ◽  
Hiv Positive Mothers ◽  
Hiv Exposed ◽  
Cluster Randomized ◽  
Infant Pair

scholarly journals Impact of the Umoyo mother-infant pair model on HIV-positive mothers’ social support, perceived stigma and 12-month retention of their HIV-exposed infants in PMTCT Care: Evidence from a cluster randomised control trial in Zambia

2019 ◽  
Author(s):  
Sydney Chauwa Phiri ◽  
Sandra Mudhune ◽  
Margaret L Prust ◽  
Prudence Haimbe ◽  
Hilda Shakwelele ◽  
...  
Keyword(s):  
Public Health ◽  
Social Support ◽  
Health System ◽  
T Test ◽  
Perceived Stigma ◽  
Hiv Exposed Infants ◽  
Pair Model ◽  
Hiv Exposed ◽  
The Impact ◽  
Infant Pair

Abstract Background Public health systems in resource-constrained settings have a critical role to play in the elimination of HIV transmission but are often financially constrained. This study is an evaluation of a mother-infant-pair model called “Umoyo”, which was designed to be low cost and scalable in a public health system. Facilities with the Umoyo model dedicate a clinic day to provide services to only HIV-exposed-infants (HEIs) and their mothers. Such models are in operation with reported success in Zambia but have not been rigorously tested. This work establishes whether the Umoyo model would improve 12-month retention of HEIs. Methods A cluster randomized trial including 28 facilities was conducted across two provinces of Zambia to investigate the impact on 12-month retention of HEIs in care. These facilities were offering prevention of mother to child transmission (PMTCT) services and supported by the same implementing partner. Randomization was achieved by use of the covariate constrained optimization technique. Secondary outcomes included the impact of Umoyo clinics on social support and perceived HIV stigma among mothers. For each of the outcomes, a difference-in-difference analysis was conducted at the facility level using the unweighted t-test. Results From 13 control (12-month retention at endline: 45%) and 11 intervention facilities (12-month retention at endline: 33%), it was found that Umoyo clinics had no impact on 12-month retention of HEIs in the t-test (-11%; 99% CI: -40.1%, 17.2%). Regarding social support and stigma, the un-weighted t-test showed no impact though sensitivity tests showed that Umoyo had an impact on increasing social support (0.31; 99% CI: 0.08, 0.54) and reducing perceived stigma from health care workers (-0.27: 99% CI: -0.46, -0.08). Conclusion The Umoyo approach of having a dedicated clinic day for HEIs and their mothers did not improve retention of HEIs though there are indications that it can increase social support among mothers and reduce stigma. Without further support to the underlying health system, based on the evidence generated through this evaluation, the Umoyo clinic day approach on its own is not considered an effective intervention to increase retention of HIV-exposed infants.

scholarly journals Can autonomy support have an effect on type 2 diabetes glycemic control? Results of a cluster randomized controlled trial

2020 ◽  
Vol 8 (1) ◽  
pp. e001018
Author(s):  
Qingping Yun ◽  
Ying Ji ◽  
Shenglan Liu ◽  
Yang Shen ◽  
Xuewen Jiang ◽  
...  
Keyword(s):  
Social Support ◽  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Support Group ◽  
Autonomy Support ◽  
Controlled Trial ◽  
Support Intervention ◽  
Randomized Controlled ◽  
Cluster Randomized

ObjectivesTo assess whether social support or autonomy support intervention for patients with type 2 diabetes can achieve glycemic control at the end of intervention, and to test whether the glycemic control effect can be maintained for a long time.Research design and methodsIn this cluster randomized controlled trial, 18 community healthcare stations (CHSs) were randomized to the following: (1) usual care group (UCG) offering regular public health management services, (2) social support group (SSG) providing 3-month social support intervention based on problem solving principles, and (3) autonomy support group (ASG) offering 3-month autonomy support intervention based on self-determination theory. A total of 364 patients registered in the CHSs were enrolled into either of the three groups. The primary outcome was hemoglobin A1c (HbA1c), and secondary outcomes were diabetes self-management (DSM) behaviors. Assessment was conducted at baseline and at 3 and 6 months.ResultsPatients in ASG achieved better HbA1c reduction at the end of intervention (0.53% or 7.23 mmol/mol, p<0.001) than those in the UCG and successfully maintained it up to 6 months (0.42% or 5.41 mmol/mol, p<0.001). However, patients in SSG did not experience significant change in HbA1c at 3 or 6 months when compared with patients in UCG. Besides, patients in both the SSG (0.12, p<0.05) and ASG (0.22, p<0.001) experienced improvement in exercise at 3 months. Patients in ASG sustained improvement in exercise up to 6 months (0.21, p<0.001), but those in the SSG did not.ConclusionsAutonomy support for patients with type 2 diabetes could help achieve glycemic control at the end of intervention and successfully maintain it up to 6 months. These findings indicate that autonomy support has positive long-term effects on DSM behaviors and glycemic control and can be recommended in future diabetes intervention programs.Trial registration numberChiCTR1900024354.

scholarly journals Assessing Water Filtration and Safe Storage in Households with Young Children of HIV-Positive Mothers: A Randomized, Controlled Trial in Zambia

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e46548 ◽  
Author(s):  
Rachel Peletz ◽  
Martin Simunyama ◽  
Kelvin Sarenje ◽  
Kathy Baisley ◽  
Suzanne Filteau ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Young Children ◽  
Controlled Trial ◽  
Water Filtration ◽  
Hiv Positive ◽  
Safe Storage ◽  
Randomized Controlled ◽  
Hiv Positive Mothers

scholarly journals Impact of Umoyo mother-infant pair clinics on HIV-positive mothers’ social support, perceived stigma and 12-month retention of their HIV-exposed infants in PMTCT Care: Evidence from a cluster randomised control trial in Zambia

2019 ◽  
Author(s):  
Sydney Chauwa Phiri ◽  
Sandra Mudhune ◽  
Margaret L Prust ◽  
Prudence Haimbe ◽  
Hilda Shakwelele ◽  
...  
Keyword(s):  
Public Health ◽  
Social Support ◽  
Health System ◽  
T Test ◽  
Randomised Control Trial ◽  
Perceived Stigma ◽  
Hiv Exposed Infants ◽  
Hiv Exposed ◽  
The Impact ◽  
Infant Pair

Abstract Background Public health systems in resource constrained settings have a critical role to play in the elimination of vertical HIV transmission but are unable to carry out some of the promising interventions such as mother-to-mother peer support programs due to financial constraints. This study is an evaluation of a mother-infant-pair clinic called Umoyo, which was designed to be scalable in a public health system due to the relatively low costs required. Umoyo clinics dedicate a clinic day to provide services to only HIV-exposed-infants (HEIs) and their mothers. Such models are in operation with reported success in Zambia but have not been rigorously tested. Methods A cluster randomized trial including 28 facilities was conducted across two provinces of Zambia to investigate 12-month retention of HEIs in care. These were facilities that were offering prevention of mother to child transmission (PMTCT) services and supported by the same implementing partner. Random allocation was achieved by use of the covariate constrained optimization technique. The primary outcome of interest was to establish whether Umoyo clinic days would improve 12-month retention of HEIs. Secondary outcomes included the impact of Umoyo clinics on social support and perceived HIV stigma among mothers. For each of the outcomes, a difference-in-difference analysis was conducted at the facility level using unweighted t-test. Results From 13 control and 11 intervention facilities, it was found that Umoyo clinics had no impact on 12-month retention of HEIs in the t-test (-11%; 99% CI: -40.1%, 17.2%). Regarding social support and stigma, the un-weighted t-test showed no impact though sensitivity tests showed that Umoyo had an impact on increasing social support and reducing perceived stigma from health care workers. Conclusion The Umoyo approach of having a dedicated clinic day for HEIs and their mothers did not improve retention of HEIs though there are indications that it can increase social support among mothers and reduce stigma. Without further support to the underlying health system, based on the evidence generated through this evaluation, the Umoyo clinic day approach on its own is not considered an effective intervention to increase retention of HIV-exposed infants.Trial Registration Pan African Clinical Trial Registry (PACTR201702001970148) Prospectively registered on January 13, 2017. URL https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=1970

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