Genetic uniformity, geographical spread and anthropogenic habitat modifications of lymnaeid vectors found in a One Health initiative in the highest human fascioliasis hyperendemic of the Bolivian Altiplano

In this chapter, the author aim to approach new ways to understand how emerging technologies can better be applied in organizational contexts. For this purpose, collaborative methodological approaches were addressed—multi, inter, and transdisciplinary paradigms—aiming to promote a better level both of comprehension and adoption of technologies, paying special attention to the healthcare sector and to the One Health initiative, just defined as an interdisciplinary front. As an overall goal for the chapter, the adoption of those methodological principles is advised to the reader, enabling a better understanding of those technologies and their way to be effectively implemented.

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Local Veterinary Diagnostic Laboratory, a Model for the One Health Initiative

Veterinary Clinics of North America Small Animal Practice ◽

10.1016/j.cvsm.2008.10.018 ◽

2009 ◽

Vol 39 (2) ◽

pp. 373-384 ◽

Cited By ~ 1

Author(s):

Gundula Dunne ◽

Nikos Gurfield

Keyword(s):

One Health ◽

Diagnostic Laboratory ◽

Health Initiative ◽

The One

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Strengthening the One Health Agenda: The Role of Molecular Epidemiology in Aspergillus Threat Management

Genes ◽

10.3390/genes9070359 ◽

2018 ◽

Vol 9 (7) ◽

pp. 359 ◽

Cited By ~ 3

Author(s):

Eta Ashu ◽

Jianping Xu

Keyword(s):

Public Health ◽

Molecular Epidemiology ◽

One Health ◽

Species Level ◽

Aspergillus Species ◽

Diagnostic Tools ◽

Health Initiative ◽

Threat Management ◽

The One

The United Nations’ One Health initiative advocates the collaboration of multiple sectors within the global and local health authorities toward the goal of better public health management outcomes. The emerging global health threat posed by Aspergillus species is an example of a management challenge that would benefit from the One Health approach. In this paper, we explore the potential role of molecular epidemiology in Aspergillus threat management and strengthening of the One Health initiative. Effective management of Aspergillus at a public health level requires the development of rapid and accurate diagnostic tools to not only identify the infecting pathogen to species level, but also to the level of individual genotype, including drug susceptibility patterns. While a variety of molecular methods have been developed for Aspergillus diagnosis, their use at below-species level in clinical settings has been very limited, especially in resource-poor countries and regions. Here we provide a framework for Aspergillus threat management and describe how molecular epidemiology and experimental evolution methods could be used for predicting resistance through drug exposure. Our analyses highlight the need for standardization of loci and methods used for molecular diagnostics, and surveillance across Aspergillus species and geographic regions. Such standardization will enable comparisons at national and global levels and through the One Health approach, strengthen Aspergillus threat management efforts.

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