scholarly journals The clinical profile, hematological parameters and liver transaminases of dengue NS1 Ag positive patients admitted to Jaffna Teaching Hospital, Sri Lanka

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
T. T. P. Jayadas ◽  
T. Kumanan ◽  
V. Arasaratnam ◽  
K. Gajapathy ◽  
S. N. Surendran
Keyword(s):  
Teaching Hospital ◽  
Hematological Parameters ◽  
Severe Form ◽  
Significant Rise ◽  
Liver Transaminase ◽  
Clinical Phase ◽  
Critical Phase ◽  
Liver Transaminases ◽  
Medical Wards ◽  
Symptoms And Signs

Abstract Objective Objective of the study is to evaluate the on-admission day symptoms and signs, clinical, hematological parameters and liver transaminases of the dengue NS1 positive patients who got admitted on different clinical phases [Febrile phase (day 1–3) and Critical phase(day 4–5)] of dengue at medical wards of Jaffna Teaching Hospital. Results Blood samples were collected from 150 suspected dengue patients from day 1 to 5 of the illness. Seventy-eight patients were positive for dengue NS1, according to the WHO proposed dengue clinical phase framework 37 patients were from febrile phase and 41 patients from critical phase. Patients who admitted on critical phase framework suffered from leukopenia and thrombocytopenia. Nine patients had the evidence of leakage with fever and the leakers had significant rise in hemoglobin, hematocrit and liver transaminase levels which are considered as severe form of the disease.

scholarly journals The clinical profile, hematological parameters and liver transaminases of Dengue NS1 Ag positive patients admitted to Jaffna Teaching Hospital, Sri Lanka

2019 ◽  
Author(s):  
T. T. P. Jayadas ◽  
T. Kumanan ◽  
V. Arasaratnam ◽  
K. Gajapathy ◽  
Sinnathamby Noble Surendran
Keyword(s):  
Teaching Hospital ◽  
Hematological Parameters ◽  
Severe Form ◽  
Significant Rise ◽  
Liver Transaminase ◽  
Clinical Phase ◽  
Critical Phase ◽  
Liver Transaminases ◽  
Medical Wards ◽  
Symptoms And Signs

Abstract Objective Objective of the study is to evaluate the on-admission day symptoms and signs clinical, hematological parameters and liver transaminases of the dengue NS1 positive patients who got admitted on different clinical phases (Febrile phase (day 1-3) and Critical phase(day 4-5) ) of dengue at medical wards of Jaffna Teaching Hospital. Results Blood samples were collected from 150 suspected dengue patients from day 1 to 5 of the illness. Seventy-eight patients were positive for Dengue NS1, according to the WHO proposed dengue clinical phase framework 37 patients were from febrile phase and 41 patients from critical phase. Patients who admitted on critical phase framework suffered from leukopenia, thrombocytopenia. 09 patients had the evidence of leakage with fever and the leakers had significant rise in hemoglobin, hematocrit and liver transaminase levels which are considered as severe form of disease.

scholarly journals The clinical profile, hematological parameters and liver transaminases of Dengue NS1 Ag positive patients admitted to Jaffna Teaching Hospital, Sri Lanka

2019 ◽  
Author(s):  
T. T. P. Jayadas ◽  
T. Kumanan ◽  
V. Arasaratnam ◽  
K. Gajapathy ◽  
Sinnathamby Noble Surendran
Keyword(s):  
Teaching Hospital ◽  
Hematological Parameters ◽  
Severe Form ◽  
Significant Rise ◽  
Liver Transaminase ◽  
Clinical Phase ◽  
Critical Phase ◽  
Liver Transaminases ◽  
Medical Wards ◽  
Symptoms And Signs

Abstract Objective Objective of the study is to evaluate the on-admission day symptoms and signs clinical, hematological parameters and liver transaminases of the dengue NS1 positive patients who got admitted on different clinical phases (Febrile phase (day 1-3) and Critical phase(day 4-5) ) of dengue at medical wards of Jaffna Teaching Hospital. Results Blood samples were collected from 150 suspected dengue patients from day 1 to 5 of the illness. Seventy-eight patients were positive for Dengue NS1, according to the WHO proposed dengue clinical phase framework 37 patients were from febrile phase and 41 patients from critical phase. Patients who admitted on critical phase framework suffered from leukopenia, thrombocytopenia. 09 patients had the evidence of leakage with fever and the leakers had significant rise in hemoglobin, hematocrit and liver transaminase levels which are considered as severe form of disease.

scholarly journals The clinical profile, hematological parameters and liver transaminases of Dengue NS1 Ag positive patients admitted to Jaffna Teaching Hospital, Sri Lanka

2019 ◽  
Author(s):  
T. T. P. Jayadas ◽  
T. Kumanan ◽  
V. Arasaratnam ◽  
K. Gajapathy ◽  
Sinnathamby Noble Surendran
Keyword(s):  
Teaching Hospital ◽  
Hematological Parameters ◽  
Severe Form ◽  
Significant Rise ◽  
Severe Thrombocytopenia ◽  
Liver Transaminase ◽  
Ns1 Antigen ◽  
Liver Transaminases ◽  
Medical Wards ◽  
Symptoms And Signs

Abstract Objective Objective of the study is to evaluate the symptoms and signs and nonspecific clinical and laboratory parameters of the dengue NS1 positive patients on the admission from day1 to day 5 at medical wards of Jaffna Teaching Hospital. Results Blood samples were collected from 150 consecutive suspected dengue patients from day 1 to 5 of the illness. Seventy-eight patients were positive for Dengue NS1. Patients who had NS1 positivity after 3days of illness suffered from severe form of disease and patients with severe thrombocytopenia had significant rise in hemoglobin, hematocrit and liver transaminase levels which are considered as severe form of disease. Severe thrombocytopenia patients had complicated illness. This shows longevity presence of NS1 antigen could lead to severe form of dengue and could be a prognostic marker of dengue outcome.

Pesticides Residues in Blood Serum and Their Adverse Effects on Multi- Biomarkers in Occupationally Exposed Greenhouse Workers: A Cross-Sectional Study in Hamadan City, Iran

2021 ◽  
Author(s):  
Mostafa Leili ◽  
Abolfazl Ghafouri Khosrowshahi ◽  
Jalal Poorolajal ◽  
Fateme Samiee ◽  
Mohammad Taghi Samadi ◽  
...  
Keyword(s):  
Blood Serum ◽  
Crop Production ◽  
Hematological Parameters ◽  
Severe Form ◽  
Mean Corpuscular Hemoglobin ◽  
Adult Males ◽  
Corpuscular Hemoglobin ◽  
Cross Sectional ◽  
Pesticides Residues ◽  
Greenhouse Workers

Abstract The cultivation of greenhouse crops is the most severe form of crop production in Iran, and vast quantities of unreasonable pesticides are being utilized to control pests. The residual level of blood pesticides and its correlation with multi- biomarkers were determined to evaluate the adverse health consequences on greenhouse workers in the Hamdan city of Iran. Participants were 180 adult males, including 90 greenhouse workers exposed to pesticides and 90 control individuals. The residue analyses revealed that 64 out of the 90 workers had residues of dichlorvos, diazinon, and chlorpyrifos in their blood serum; and 56.25% out of these workers were exposed for > 15 years period. The residues of all three pesticides were higher than the no observable adverse effect level (NOAEL) in all the exposure duration categories. Comparisons of hematological parameters showed that mean monocyte (P < 0.001), lymphocyte (P < 0.001) and platelet counts (P = 0.001), mean platelet volume (P = 0.002), and plateletcrit (PCT) (P < 0.001) were significantly higher in workers than in controls, whereas hemoglobin (HB) (P = 0.028), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentrations (MCHC) (P < 0.001) were lower in workers than controls. These results show that exposure to different pesticides was associated with alterations in some biochemical and hematological parameters. Prevention and intervention programs can be effective in eliminating pesticide-related alterations among agricultural workers.

Pattern of cancer deaths in the medical wards of a teaching hospital in South East Nigeria

2013 ◽  
Vol 16 (4) ◽  
pp. 505 ◽  
Author(s):  
EB Arodiwe ◽  
SO Ike ◽  
SC Nwokediuko ◽  
CK Ijoma ◽  
II Ulasi
Keyword(s):  
Teaching Hospital ◽  
Medical Wards

Antibiotic consumption and healthcare associated infection in a third level Italian hospital

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
F Gori ◽  
N Vonci ◽  
A Tinturini ◽  
C Basagni ◽  
G Messina ◽  
...  
Keyword(s):  
Infection Control ◽  
Teaching Hospital ◽  
General Medicine ◽  
Venous Catheter ◽  
Antibiotic Consumption ◽  
Healthcare Associated Infection ◽  
Peripheral Venous Catheter ◽  
Control And Prevention ◽  
Medical Wards ◽  
Clinical Records

Abstract Background The extended length of stay (LoS) is one of the main causes of hospital infections (HAI), followed by an increase in antibiotics consumption. The final step is the development of multiresistant microorganisms, with a consequent increase in costs for the national healthcare system. Aim of this study is to evaluate the prevalence of HAI and to analyze ATB consumption in a teaching hospital Methods Between 17-21 June 2019 the infection control team collected the clinical records of 425 patients to perform a point of prevalence analysis (PPA). Eligible patients were hospitalized in surgical and medical wards of the teaching Hospital (615 beds) in Siena, Italy. For each patients according to guidelines of European Centers for Disease Control and Prevention (ECDC 4.2) we searched for evidence of HAI and for all indication of ATB consumption. Data were processed using Stata12 Results Overall 425 patients have been analyzed (48.24% female), mean age was 60.88 (SD 26.11) years, mean LoS 8.37 (min 1 max 86) days. Patients were admitted mostly in General Medicine wards (48.94%); 34% underwent surgery. 63.8% of patients had Peripheral Venous Catheter, 20% Central Venous Catheter and 31.06% Urinary Catheter. Twenty-nine HAI were discovered (PPA 6.82%); the higher prevalence (19.23%) was in Intensive Care Unit. LoS (OR:1.07;IC95%1.04-1.1) and devices (OR:2.17;IC95%1.39-3.37) were the two variables that significantly influenced the infection risk. Forty-six percent of all patients received ATB, the most used were third generation Cephalosporines (26,18%), followed by Penicillines (24,73%). The main use was to treat community infections (62.12%), followed by medical prophylaxis (30.81%) Conclusions PPA of HAI was 6.82%, comparable to 2017 national PPA (6.5%); prolonged LoS is probably the main cause of this result. Our analysis showed that ATB consumption was quite high, in agreement with the Italian prevalence (44.9%), but the percentage of medical prophylaxis was still high. Key messages The way to achieve the health care infection control is still long, the length of the hospitalization could be a field to be improved. High consumption of antibiotics for prophylaxis is still the main point to fight in the battle against the multiresistant microorganisms.

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