scholarly journals Impact of comorbidities on risk of angioedema without urticaria in elderly patients

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Andrzej Bożek ◽  
Magdalena Zając
Keyword(s):  
Elderly Population ◽  
The Elderly ◽  
Inclusion Criteria ◽  
Hashimoto’S Disease ◽  
Detailed Medical History ◽  
Icd 10 ◽  
History Of ◽  
Hashimoto's Disease ◽  
Low Levels ◽  
Potential Factors

Abstract Background Angioedema without urticaria (AWU) is a disease found in the elderly population but is still poorly studied. The aim of this study was to investigate potential factors, especially comorbidities, that may affect the induction of angioedema without urticaria in patients over 60 years of age. Methods This was an observational, retrospective study of 242 patients with a diagnosis of AWU and 263 controls. The inclusion criteria were as follows: at least one episode of confirmed AWU based on the ICD-10 code (T78.3) that required treatment in the last 15 years (2004–2019); age above 60 years; detailed medical history of comorbidities; and details regarding the use of drugs at that time. Serum functional and quantitative C1 inhibitor assays were performed, and serum C4 was measured. Comorbidities were grouped into the following panels: autoimmune, cancer, cardiac, metabolic, respiratory and allergic, liver failure and renal failure. Individual diseases were checked according to ICD code and treatment. Results In 1 (0.4%) patient, hereditary angioedema was confirmed. Decreased levels of C1INH were observed in 4 (1.65%) patients, dysfunction of C1INH was observed in 5 (1.76%) patients, and low levels of C4 were observed in 9 (3.71%) patients in the study group. The multiple logistic regression model revealed that patients with hyperuricemia or Hashimoto’s disease had a significantly higher chance of angioedema (OR = 3.21, 95% CI 2.92–3.66, p = 0.002; OR = 1.78 95% CI 1.37–2.21, p = 0.034, respectively). Conclusion The obtained results may indicate a significant influence of hyperuricemia or Hashimoto’s disease on angioedema manifestations.

scholarly journals Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Steven Emil Gerges ◽  
Mahmoud Hemeda El Rakawy ◽  
Naglaa Mohammed El Khayat ◽  
Yousry Abo Elnaga Abdelhamid ◽  
Ahmed Mohammed Hazzou ◽  
...  
Keyword(s):  
Predictive Factors ◽  
Elderly Population ◽  
Laboratory Data ◽  
The Elderly ◽  
Medical Comorbidities ◽  
Mri Brain ◽  
Group Data ◽  
History Of ◽  
Eeg Changes ◽  
International League

Abstract Background Elderly people with epilepsy are large, but neglected group. Data on the predictive factors for recurrent seizures in the elderly population are inconclusive or are not known for the majority of patients. This is especially true for the Egyptian population as no specific study was concluded to address this issue before. Objectives The aim of this study was to detect the predictive factors of epilepsy outcome in a sample of Egyptian aged population. Materials and methods A total of 100 patients aged 50 years or older with epilepsy diagnosed according to International League Against Epilepsy (ILAE) latest definition were included in the study and followed up for 6 months as regards seizure control. All participants were prospectively evaluated for epidemiological, clinical, radiological, electrodiagnostic, and laboratory data. Results The outcome was statistically significant affected in relation to absence of medical comorbidities (P = 0.037), seizure etiology (P = 0.007), history of status epilepticus (P <  0.001), MRI brain findings (P = 0.005), EEG changes (P <  0.001), Ca (P = 0.01), and Mg level (P = 0.046). Conclusion We conclude that aged Egyptian epileptic population with no medical comorbidities, normal MRI brain, or normal EEG can be predicted to have good outcome of their epilepsy while patients with post stroke epilepsy, abnormal MRI brain, and abnormal EEG, with low serum Ca or Mg level can be predicted to have poor outcome.

A Case Report of Delirium Induced by Herbal Laxative Senna

2021 ◽  
Vol 11 (6) ◽  
pp. 231-233
Author(s):  
Nimitha K J ◽  
Porimita Chutia ◽  
Pooja Misal
Keyword(s):  
Case Report ◽  
Serum Sodium ◽  
Elderly Population ◽  
Oral Intake ◽  
Mental Illnesses ◽  
Electrolyte Imbalance ◽  
Normal Limits ◽  
Icd 10 ◽  
Current Scenario ◽  
History Of

Constipation is one major complaint in elderly population. It may be due to physiological and anatomical reasons of aging, but it can be also due chronic medical and mental illnesses and due to use of multiple medications. Constipation itself is a precipitating factor for delirium. Drugs used for constipation can also be the culprit. A 64-year-old female who had a history of hypertension and chronic constipation presented with symptoms of confused and altered behavior, decreased oral intake, decreased sleep. On history taking it was known that she was using Herbal medication containing senna glycoside and other compounds since 8-9months. On examination she had signs of dehydration, disoriented and attention was impaired. On investigation her serum sodium was 122.6 mmol/ and other investigations were within normal limits. She was diagnosed as a case of Delirium according to ICD-10 criteria. Her dehydration was corrected by giving intravenous fluids and serum sodium level was corrected using salt capsules 2 tablets thrice daily. For disturbed sleep she was prescribed Tab Melatonin 10mg at bedtime and constipation was treated with per rectal enema and syrup lactulose 30ml at bedtime. Patient improved in 1 week time. Senna a herbal laxative used to treat constipation. It can alter intestinal electrolyte transportation and irritates intestinal mucosa. It is due to increased peristalsis and increased defecation and even diarrhea Prolonged use can cause dehydration, electrolyte imbalance and delirium. Senna, an over-the-counter laxative with FDA approval is a matter of concern in the current scenario. This case report warns into the judicious use of laxatives containing senna in elderly population. Key words: Delirium, Herbal Laxative, Senna, Constipation.

scholarly journals Prevalence of Anaemia among the Elderly in Malaysia and Its Associated Factors: Does Ethnicity Matter?

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Muslimah Yusof ◽  
S. Maria Awaluddin ◽  
Maisarah Omar ◽  
Noor Ani Ahmad ◽  
Fazly Azry Abdul Aziz ◽  
...  
Keyword(s):  
Older People ◽  
Point Of Care ◽  
Clinical Information ◽  
The Elderly ◽  
Demographic Information ◽  
Point Of Care Testing ◽  
Future Studies ◽  
History Of ◽  
Potential Factors ◽  
Structured Questionnaire

Introduction. Anaemia is common among the elderly, yet it remains an underresearched clinical condition. This study investigates ethnic differences in prevalence of anaemia and identifies potential factors associated with anaemia in the elderly. Methods. Data from the National Health & Morbidity Survey (NHMS) 2015 conducted by Ministry of Health was analyzed. Haemoglobin levels were measured using point-of-care testing, HemoCue® Hb 201+ System©, from consenting individuals. Demographic information and other clinical information were obtained through a structured questionnaire. Descriptive and multivariate analyses were conducted and significant results were presented as adjusted odds ratio. Results. A total of 3794 participants aged 60 years and older responded to the anaemia module with a response rate of 93.7%. 64.0% of respondents were of Malay ethnicity, 21.6% were Chinese, 6.1% were Indians, and 8.3% were of other ethnicities. The overall prevalence of anaemia among older people was 35.3%. The highest prevalence of anaemia was found among respondents of Indian ethnicity (45.5%). The Indian (aOR: 1.72; 95% CI 1.26–2.34) and Malay (aOR: 1.25; 95% CI 1.04–1.49) ethnic groups were more likely to be anaemic in comparison to those of Chinese ethnicity. Anaemia in older people was also associated with increasing age, history of hospital admission, and the presence of diabetes mellitus. Conclusion. Anaemia in the elderly is associated with Indian and Malay ethnicities, increasing age, hospitalization, and diabetes. Our study has identified important information on a common condition which will guide and assist future studies in reducing the burden of anaemia.

scholarly journals History of Hashimoto’s Disease

2002 ◽  
Vol 49 (4) ◽  
pp. 387-387
Author(s):  
JUNJI KONISHI
Keyword(s):  
Hashimoto’S Disease ◽  
History Of ◽  
Hashimoto's Disease

scholarly journals Isolated Cecal Necrosis: Report of 2 Cases

2021 ◽  
Author(s):  
Nizar Kardoun ◽  
Zied Hadrich ◽  
Rahma Daoud ◽  
Houssem Harbi ◽  
Salah Boujelben ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Appendicitis ◽  
Rare Variant ◽  
Ischemic Colitis ◽  
Elderly Population ◽  
The Elderly ◽  
Female Patients ◽  
History Of

Isolated cecal necrosis is a rare variant of ischemic colitis which typically simulates the presentation of acute appendicitis. The elderly population is the most affected. We report 2 cases of isolated caecal necrosis, which were preoperatively diagnosed, in 2 female patients with a history of hypertension and renal failure.

scholarly journals Background Factors Involved in the Epidemiology of Functional Constipation in the Japanese Population

2021 ◽  
Author(s):  
Sayuri Yamamoto ◽  
Wataru Ohashi ◽  
Yoshiharu Yamaguchi ◽  
Shunsuke Inamoto ◽  
Akira Koshino ◽  
...  
Keyword(s):  
Japanese Population ◽  
Elderly Population ◽  
Clinical Symptoms ◽  
Functional Constipation ◽  
The Elderly ◽  
Internet Survey ◽  
Comprehensive Management ◽  
History Of ◽  
Characteristic Features

Abstract Background: Little is known about the prevalence and epidemiology of functional constipation (FC), a functional bowel disorder with symptoms of constipation. This study aimed to examine the prevalence, population composition, lifestyle, quality of life, and clinical characteristics of individuals with and without FC and of individuals with a strong or weak awareness of constipation. Methods: An internet survey revealed that 262 (8.7%) out of 3,000 respondents from the general Japanese population were diagnosed with FC. Moreover, all respondents were classified according to their awareness of constipation (i.e. strong or weak), and their characteristic features were compared. Results: FC occurrence was associated with the elderly population, females, and homemakers. Its onset was associated with a change in the frequency of bowel movement, sensation of incomplete or hardly any evacuation, and the use of manual maneuvers, which are consequential clinical symptoms of FC. Subjects with FC also frequently skipped breakfast, had insufficient sleep, had more severe constipation, and had purchased laxatives in pharmacies or online more often than individuals without FC. A strong awareness of constipation was significantly more prevalent among women and homemakers. A history of anemia and cardiovascular disease was significantly more frequent in the strong awareness group, whereas a history of hypertension was more frequent in the weak awareness group.Conclusions: Based on the understanding of the characteristic features of FC, appropriate and comprehensive management considering the patient’s symptoms and lifestyle should be provided.

scholarly journals Being elderly with functional dependence and their family caregivers

2012 ◽  
Vol 25 (spe1) ◽  
pp. 143-149 ◽  
Author(s):  
Amanda Maria Souza de Oliveira ◽  
Larissa Chaves Pedreira
Keyword(s):  
Family Relationships ◽  
Semantic Analysis ◽  
Functional Dependence ◽  
Social Situation ◽  
The Elderly ◽  
Study Data ◽  
Online Database ◽  
Inclusion Criteria ◽  
Electronic Library ◽  
History Of

OBJECTIVE: To identify the authors` point of discussion on the elderly with functional dependence, correlating it with the ontological time discussed in Heidegger. METHODS: This is a bibliographic, systematic and qualitative study. Data was collected in the Scientific Electronic Library Online database. A total of 123 studies were identified, 15 studies were included considering the inclusion criteria. RESULTS: Based on the semantic analysis of Bardin, the following categories of analysis were established: being caregiver for the elderly with functional dependence, being elderly with functional dependence, family dynamics. CONCLUSION: It was understood that factors related to the worldliness of these people as family relationships, support of formal and informal services, economic and social situation, among others, are part of the history of these people influencing their modes of being. Searching to understand these factors is important to promote the health of these people, thinking of the biological and existential care.

scholarly journals Effects of the Application of a Program of Adapted Utilitarian Judo (JUA) on the Fear of Falling Syndrome (FOF) for the Health Sustainability of the Elderly Population

2018 ◽  
Vol 15 (11) ◽  
pp. 2526 ◽  
Author(s):  
Luis Toronjo-Hornillo ◽  
Carolina Castañeda-Vázquez ◽  
María Campos-Mesa ◽  
Gloria González-Campos ◽  
Juan Corral-Pernía ◽  
...  
Keyword(s):  
Elderly People ◽  
Experimental Research ◽  
Functional Assessment ◽  
Elderly Population ◽  
Intervention Program ◽  
Fear Of Falling ◽  
The Elderly ◽  
Quasi Experimental ◽  
History Of ◽  
Experimental Group

This research analyzes the fall history of a group of elderly people and studies the effects of an intervention program based on Adapted Utilitarian Judo (JUA) to teach fall control in subjects with fear of falling syndrome (FOF). We adopted a quasi-experimental research design with pre-post measurement of the experimental group, in a healthy, pre-fragile sample of 12 women aged 71.5 ± 8 years, chosen using non-probabilistic-incidental accessibility sampling. The WHO questionnaire was used for the functional assessment of the fall. To evaluate FOF, we applied the 16-item version of the Falls Efficacy Scale-International (FES-I), (pretest and posttest). This intervention program was based on Adapted Utilitarian Judo and conducted over 8 weeks, with two 60-minute sessions each week. After analyzing the scores obtained by the subjects in the pre and post FES-I, we found that the intervention with the JUA program had been significant for the experimental group with p ≤ 0.004, and there was an 11.9% decrease in the fear of falling (FES-I pos = 18.17). The results show that after the application of the JUA program there were significant improvements in subjects’ perception of FOF, with this being greater in those who had the highest levels of fear of falling before the intervention.

History of lifetime smoking, smoking cessation and cognitive function in the elderly population

2013 ◽  
Vol 28 (10) ◽  
pp. 823-831 ◽  
Author(s):  
Ute Mons ◽  
Ben Schöttker ◽  
Heiko Müller ◽  
Matthias Kliegel ◽  
Hermann Brenner
Keyword(s):  
Smoking Cessation ◽  
Cognitive Function ◽  
Elderly Population ◽  
The Elderly ◽  
History Of

scholarly journals Plasma lutein and zeaxanthin and the risk of age-related nuclear cataract among the elderly Finnish population

2011 ◽  
Vol 108 (1) ◽  
pp. 148-154 ◽  
Author(s):  
Jouni Karppi ◽  
Jari A. Laukkanen ◽  
Sudhir Kurl
Keyword(s):  
Elderly Population ◽  
Proportional Hazards Model ◽  
Disease Risk ◽  
Plasma Concentrations ◽  
The Elderly ◽  
Cox Proportional Hazards Model ◽  
Elderly Subjects ◽  
Nuclear Cataract ◽  
Age Related ◽  
History Of

Oxidative stress plays an important role in cataractogenesis. Previous studies have shown that long-term dietary intake of antioxidants (lutein and zeaxanthin) may decrease the risk of age-related cataracts. The aim of the present study was to examine whether plasma concentrations of lutein and zeaxanthin are related to age-related nuclear cataract in the elderly population. Subjects were participants in the Kuopio Ischaemic Heart Disease Risk Factor Study and they were classified into tertiles according to plasma concentrations of lutein and zeaxanthin. The association of plasma lutein and zeaxanthin concentrations with age-related nuclear cataract in 1689 elderly subjects (aged 61–80 years) was investigated in the present cross-sectional study by using the Cox proportional hazards model. A total of 113 cases of incident age-related cataracts were confirmed, of which 108 cases were nuclear cataracts. After adjustment for age, examination year, sex, BMI, smoking, alcohol consumption, serum LDL-cholesterol, serum HDL-cholesterol, years of education, use of oral corticosteroids, history of diabetes and history of hypertension with current use of antihypertensive medication, subjects in the highest tertiles of plasma concentrations of lutein and zeaxanthin had 42 and 41 % lower risks of nuclear cataract, respectively, compared with those in the lowest tertiles (relative risk (RR) = 0·58, 95 % CI 0·35, 0·98; P = 0·041 for lutein and RR = 0·59, 95 % CI 0·35, 0·99; P = 0·046 for zeaxanthin). In conclusion, we suggest that high plasma concentrations of lutein and zeaxanthin were associated with a decreased risk of age-related nuclear cataract in the elderly population.

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