The role of patients and healthcare workers Staphylococcus aureus nasal colonization in occurrence of surgical site infection among patients admitted in two centers in Tanzania

Background: Surgical site infection is one of the commonest complications after surgical intervention. Source of wound infections may be exogenous or endogenous. Wound swabs culture is the most frequently used method for confirming the diagnosis of surgical site infection. A regular bacteriological review is necessary to identify the causative agents and their antibiotic susceptibility pattern.Objective: The purpose of the present study was to find out the aerobic bacteria from wound swabs culture and their antibiotic susceptibility pattern.Methodology: A total of 175 wound swabs sample were collected aseptically from surgical site infection during the study period. Standard bacteriological methods were used for isolation and identification of organisms and their susceptibility pattern.Results: A total of 175 wound swab samples were collected from surgery departments. Out of 175 samples 102 (58.28%) were positive by culture. Among the isolated organisms the gram negative bacilli were predominant 67 (65.68%) than the gram positive cocci 35 (34.32%).The most common isolated bacteria were Escherichia.coli 30(29.41%) followed by Staphylococcus aureus 28 (27.45%) Pseudomonous areuginosa 20(29.85%), Acinetobacter spp 08(11.94%), Coaggulase negative Staphylococcus (CONS) 07(6.86%) Klebsiella pneumoniae 05(4.90%), Proteus spp 03(4.45%), and Citobacter spp 01(1.49%). Among the total 175 samples 114(65.14%) were collected from male patients and 61(34.86%) were from female patients. All the isolated gram negative bacilli showed resistant to all antibiotics and all isolated gram positive cocci were resistant to all antibiotics except Linezolid. Among the isolated Staphylococcus aureus 8 (24.85%) were MRSA and one (3.57%) were VRSA. The most effective antibiotics were Amikacin, Meropenem, Imipenem and Tazobactam in this study.Conclusion: Surgical site infections remain the commonest post operative complications after surgery and one of the commonest encountered hospital acquired infections. Therefore, periodic review needs be done to find out the causative agents and their antibiotic susceptibility pattern for better treatment and managementBangladesh Journal of Infectious Disease 2015;2(2):28-32

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Effect of a single preoperative dose of oral antibiotic to reduce the incidence of surgical site infection following below-knee dermatological flap and graft repair

Dermatology Practical & Conceptual ◽

10.5826/dpc.0901a08 ◽

2019 ◽

pp. 28-35 ◽

Cited By ~ 2

Author(s):

Helena Rosengren ◽

Clare Heal ◽

Petra Buettner

Keyword(s):

Surgical Site Infection ◽

Antibiotic Prophylaxis ◽

Controlled Trial ◽

Study Groups ◽

High Dose ◽

Antibiotic Administration ◽

Oral Antibiotic ◽

Site Infection ◽

Double Blind

Background: Surgical site infection (SSI) rates for below-knee dermatological surgery are unacceptably high, particularly following complex flap and graft closures. The role of antibiotic prophylaxis for these surgical cases is uncertain. Objective: To determine whether SSI following complex dermatological closures on the leg could be reduced by antibiotic prophylaxis administered as a single oral preoperative dose. Methods: A total of 115 participants were randomized to 2 g of oral cephalexin or placebo 40-60 minutes prior to surgical incision in a prospective, randomized, double-blind, placebo-controlled trial at a primary care skin cancer clinic in North Queensland, Australia. Results: Overall 17/55 (30.9%) controls and 14/55 (25.5%) intervention participants developed infection (P = 0.525). There was no difference between the study groups in adverse symptoms that could be attributed to high-dose antibiotic administration (P = 1).

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Role of bundled intervention in reducing surgical site infection rate in gynecologic surgeries

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20201205 ◽

2020 ◽

Vol 9 (4) ◽

pp. 1457

Author(s):

Nisha Singh ◽

Shweta Rai ◽

Shuchi Agrawal ◽

Gopa Banerjee ◽

Renu Singh

Keyword(s):

Surgical Site Infection ◽

Total Duration ◽

Signs And Symptoms ◽

Antibiotic Usage ◽

Control Group ◽

Gynecological Surgery ◽

Site Infection ◽

Surgical Site Infection Rate ◽

Time Period

Background: Surgical site infection (SSI) is most common nosocomial infection (15%) among surgical patient’s and contributes significantly to morbidity and mortality. CDC (2015) provides “bundled intervention for prevention of SSI. The present study was planned to evaluate the feasibility and usefulness of these bundled intervention in reducing SSI in our setup. Objectives of this study to study the effect of bundled interventions on SSI in gynaecologic surgery.Methods: A total 50 cases undergoing gynecological surgery in elective OT included in pilot group and bundled intervention followed these pilot group cases compared with 50 control group operated in same OT in which bundled intervention not followed outcome measures recorded were Incidence of SSI, type of SSI, need for antibiotic usage, need for secondary suturing, duration of hospital stay.Results: Out of 50 subjects in pilot group, five developed signs and symptoms of SSI giving an SSI rate of 10%. Out of those five, two had superficial SSI and three had deep SSI, none of the patient had organ space SSI.SSI rate in 50 cases operated in the same operating room during the same time period without use of bundled interventions (control group) was 12%.Conclusions: Bundled approach is easy and feasible in all setups. It adds only three extra minutes to the total duration of the surgery with risk reduction of SSI.

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