scholarly journals Systematic review on diabetes mellitus and dental implants: an update

2022 ◽  
Vol 8 (1) ◽  
Author(s):  
Juliane Wagner ◽  
Johannes H. Spille ◽  
Jörg Wiltfang ◽  
Hendrik Naujokat
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Dental Implants ◽  
Dental Implant ◽  
International Diabetes Federation ◽  
Diabetic Patients ◽  
Oral Rehabilitation ◽  
Implant Surgery ◽  
Controlled Conditions ◽  
Dental Implant Surgery

Abstract Purpose Dental implant surgery was developed to be the most suitable and comfortable instrument for dental and oral rehabilitation in the past decades, but with increasing numbers of inserted implants, complications are becoming more common. Diabetes mellitus as well as prediabetic conditions represent a common and increasing health problem (International Diabetes Federation in IDF Diabetes Atlas, International Diabetes Federation, Brussels, 2019) with extensive harmful effects on the entire organism [(Abiko and Selimovic in Bosnian J Basic Med Sci 10:186–191, 2010), (Khader et al., in J Diabetes Complicat 20:59–68, 2006, 10.1016/j.jdiacomp.2005.05.006)]. Hence, this study aimed to give an update on current literature on effects of prediabetes and diabetes mellitus on dental implant success. Methods A systematic literature research based on the PRISMA statement was conducted to answer the PICO question “Do diabetic patients with dental implants have a higher complication rate in comparison to healthy controls?”. We included 40 clinical studies and 16 publications of aggregated literature in this systematic review. Results We conclude that patients with poorly controlled diabetes mellitus suffer more often from peri-implantitis, especially in the post-implantation time. Moreover, these patients show higher implant loss rates than healthy individuals in long term. Whereas, under controlled conditions success rates are similar. Perioperative anti-infective therapy, such as the supportive administration of antibiotics and chlorhexidine, is the standard nowadays as it seems to improve implant success. Only few studies regarding dental implants in patients with prediabetic conditions are available, indicating a possible negative effect on developing peri-implant diseases but no influence on implant survival. Conclusion Dental implant procedures represent a safe way of oral rehabilitation in patients with prediabetes or diabetes mellitus, as long as appropriate precautions can be adhered to. Accordingly, under controlled conditions there is still no contraindication for dental implant surgery in patients with diabetes mellitus or prediabetic conditions.

scholarly journals Comparative Evaluation of Dental Implant Failure among Healthy and Well-Controlled Diabetic Patients—A 3-Year Retrospective Study

2020 ◽  
Vol 17 (14) ◽  
pp. 5253 ◽  
Author(s):  
Mohammed Ghazi Sghaireen ◽  
Abdulrahman A. Alduraywish ◽  
Kumar Chandan Srivastava ◽  
Deepti Shrivastava ◽  
Santosh R Patil ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Retrospective Study ◽  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Control Group ◽  
Case Group ◽  
Diabetic Patients ◽  
Oral Rehabilitation ◽  
Operative Evaluation

Diabetes mellitus is known to compromise the various aspects of homeostasis, including the immune response and the composition of oral microflora. One of the oral manifestations of diabetes mellitus is tooth loss and the survival rate of dental implants chosen as a treatment modality for its rehabilitation is controversial. The current study aims to evaluate and compare the failure rate of dental implants between well-controlled diabetic and healthy patients. A retrospective study of case-control design was conceptualized with 121 well-controlled diabetic and 136 healthy individuals. Records of subjects who had undergone oral rehabilitation with dental implants between the periods of January 2013 to January 2016 were retrieved. Post-operative evaluation was carried out for all patients for about three years to assess the immediate and long-term success of the procedure. From a total of 742 dental implants, 377 were placed in well-controlled diabetic patients (case group) and 365 in healthy subjects (control group). A comparable (9.81%), but non-significant (p = 0.422) failure rate was found in the case group in comparison to the control group (9.04%). A non-significant (p = 0.392) raised number (4.98%) of failure cases were reported among females in comparison to males (4.44%). In respect to arch, the mandibular posterior region was reported as the highest failure cases (3.09%; p = 0.411), with 2.29% of cases reported in the mandibular anterior (p = 0.430) and maxillary posterior (p = 0.983) each. The maxillary anterior region was found to have the least number (1.75%; p = 0.999) of failure cases. More (4.98%; p = 0.361) cases were reported to fail during the functional loading stage in contrast to osseointegration (4.44%; p = 0.365). A well-controlled diabetic status does not impose any additional risk for individuals undergoing dental implant therapy.

scholarly journals Oral Rehabilitation on Implants and Introduction of Pathogenic Mechanisms in Relation to Oral Implants - Sugar Diabetes

2019 ◽  
Vol 70 (10) ◽  
pp. 3750-3752
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Failure Rate ◽  
Primary Stability ◽  
Advanced Technology ◽  
Diabetic Patients ◽  
Oral Rehabilitation ◽  
Complete Replacement ◽  
Oral Implants ◽  
Dental Aesthetics

Dental implants are made of medical titanium and perfectly fit into human bone tissue; the dental implant can last a lifetime. Not beeing living organic structures, there are no nerve endings, neither at the implant level nor at the artificial crown level. The use of quality implants by an experienced implantologist, assisted by advanced technology, transforms the treatment with dental implants into the medical-surgical act with the highest success rate among dental and even medical treatments.Through the complete replacement of the tooth, including the root, can artificially reproduce the function of the natural tooth, with a strong and stable base. The implant crown, made of aesthetic materials (porcelain, zirconium) and anchored to it by means of the prosthetic abutment, will be surrounded by a healthy and aesthetic gum. Especially if the prosthetic abutment (the connecting element between the implant itself and the artificial crown) will be made of zirconium - natural light will cross ceramic layers, similar to enamel and dentine, offering a white of envy and glitter to the smile. Around the porcelain crowns (whole ceramics or zirconia ceramics) the gingiva will conform healthily, without the slightest sign of inflammation. These elements, the white of the teeth and the pink of the gums define the concept of dental aesthetics. The main problems that diabetic patients may encounter, are gingival inflammation and periodontal disease, dental mobility and tooth loss. When a dental implant is influenced by the type of diabetes, its failure rate is higher in patients with type 1 diabetes than in patients with type 2 diabetes. The study included a number of 56 patients, who presented themselves for performing an implant. Of these, 7 patients did not perform an implant. Diabetes mellitus defines a chronic metabolic disorder, which may have multiple etiopathogenesis, characterized by changes in carbohydrate, lipid and protein metabolism. Stability of the implant in the bone, immediately after implantation is crucial for the success of the treatment; this immediate stability is called primary stability and is purely mechanical in nature. Keywords: Dental implants, dental treatments, diabetes, failure rate

scholarly journals Dental implants and risk of bleeding in patients on oral anticoagulants: a systematic review and meta-analysis

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Basim E. S. Dawoud ◽  
Samuel Kent ◽  
Oliver Tabbenor ◽  
Pynadath George ◽  
Jagtar Dhanda
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Bleeding Complications ◽  
Implant Surgery ◽  
Risk Of Bleeding ◽  
Implant Placement ◽  
Increased Risk ◽  
Dental Implant Surgery ◽  
Anticoagulated Patients

Abstract Background Dental implant placement is safe and predictable, yet optimal management of anticoagulated patients remains controversial. Whilst cessation of anticoagulation pre-operatively should decrease risks of bleeding, risk of thrombosis increases. We aim to define risk of bleeding in patients on oral anticoagulation who are undergoing dental implant placement, in order to establish best management. Methods This systematic review is registered with the National Institute for Health Research (NIHR) PROSPERO database (Registration No: CRD42021233929). We performed a systematic review as per Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Studies were identified using an agreed search strategy within the OVID Gateway (this included Pubmed, MEDLINE, Cochrane Collaborative). Studies assessing bleeding complications in patients who were undergoing dental implant placement were selected. The primary outcome was bleeding events in anticoagulated patients undergoing dental implant placement. Secondary outcomes included any complication requiring further intervention. Results We identified 182 studies through screening, and after review of titles and abstracts reduced this to 8 studies. In these studies, 1467 participants received at least 2366 implants. Studies were analysed for quality using the ROBINS-I risk of bias tool. Four studies were retrospective case reviews, and four were prospective reviews, three of which also blinded the operator to anticoagulation status. There was significant heterogeneity between the included studies. Meta-analysis showed an increased risk of bleeding (RR, 2.30; 95% CI, 1.25-4.24 p = 0.37 I = 7%) when implants were placed in the presence of anticoagulation however these were not clinically significant haemorrhagic events. Conclusion The continuation of anticoagulants peri-operatively during dental implant surgery does increase the risk of clinically non-significant peri- and post-operative bleeding. Dental implant surgery encompasses a broad spectrum of procedures ranging from minor to more invasive surgery with simple local haemostatic measures mitigating the risk of bleeding. The decision to discontinue anticoagulants prior to dental implant surgery must consider patient and surgical factors with the clinician undertaking a risk-balance assessment.

Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw With Plasma Rich in Growth Factors After Dental Implant Surgery: A Case Report

2019 ◽  
Vol 45 (4) ◽  
pp. 289-296 ◽  
Author(s):  
Ignacio García Gil ◽  
Barbara Molina Ponte ◽  
Sergio Trapote Mateo ◽  
Jaime Jiménez García
Keyword(s):  
Growth Factors ◽  
Dental Implants ◽  
Dental Implant ◽  
Clinical Case ◽  
Scientific Evidence ◽  
Osteonecrosis Of The Jaw ◽  
Oral Bisphosphonates ◽  
Implant Surgery ◽  
Dental Implant Surgery

Oral bisphosphonates are commonly used to improve bone density in patients who suffer from a variety of pathologies. However, they have also been known to cause bisphosphonate-related osteonecrosis of the jaws (BRONJ). The aim of this clinical case presentation is to (1) determine whether the currently recommended length of time that oral bisphosphonates should be discontinued, before performing dental implant surgery, is sufficient to prevent BRONJ and (2) to describe an alternative treatment for BRONJ. A 65-year-old female patient developed BRONJ after receiving mandibular dental implants 5 months after discontinuing alendronic acid (Fosamax). The BRONJ was treated by surgical osteotomy and plasma rich in growth factors (PRGF), and the patient was followed up with biweekly examinations, which included 0.2% chlorhexidine mouthwashes and removal of any remaining necrotic bone. The dental implants were loaded 41 weeks after surgery and followed up with periapical radiographs and implant stability quotient measurements at 3, 6, 12, and 24 months postloading. Although the Association of Oral and Maxillofacial Surgeons protocols for suspension of presurgical oral bisphosphonates were followed, this patient still developed BRONJ after implant surgery. While a multitude of treatments have been described in the literature, there is not enough scientific evidence to support any one treatment. Based on this clinical case, it can be concluded that the potential adverse effects of oral bisphosphonates on the jaws could be greater than expected and that treatment with PRGF produces promising results, although more long-term studies are necessary to confirm these findings.

scholarly journals Use of Antibiotics in Dental Implant Surgery: A Decision Based on Evidence from Systematic Review

2015 ◽  
Vol 9 (1) ◽  
pp. 137-147 ◽  
Author(s):  
Claudia Asenjo-Lobos ◽  
Jorge Jofre ◽  
Marcela Cortes ◽  
Carlos Manterola
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Implant Surgery ◽  
Dental Implant Surgery

scholarly journals Effect of Masticatory Forces Transmitted by Dental Implants on the Mandibular Bone of Patients with Type 2 Diabetes Mellitus

2015 ◽  
Vol 22 (4) ◽  
pp. 419-424
Author(s):  
Raluca-Iulia Juncar ◽  
Mihai Juncar ◽  
Florin-Onişor Gligor ◽  
Amorin-Remus Popa
Keyword(s):  
Diabetes Mellitus ◽  
Bone Resorption ◽  
Dental Implants ◽  
Dental Implant ◽  
Adult Population ◽  
Considerable Proportion ◽  
Diabetic Patients ◽  
Mandibular Bone ◽  
Implant Exposure ◽  
Bone Response

Abstract Background and Aims: Diabetes mellitus is considered to be one of the most important diseases of our society, affecting a considerable proportion of the adult population. Currently, dental implant treatment of diabetic patients is controversial, the main controversy being related to changes that occur in the jaw bones of the diabetic patient and the ensuing side effects. This preliminary study aims to evaluate the response of mandibular bone to masticatory forces transmitted by dental implants in diabetic patients. Material and Method: 11 dental implants placed in the mandible were selected, and mandibular bone resorption as a result of masticatory forces transmitted by them was evaluated. Results: The mean bone resorption rates were the following: 2.72% at the time of dental implant exposure, 10% at 3 months from dental implant exposure, and 13.63% at 6 months from exposure. Conclusions: No significant changes in mandibular bone response to the action of dental implants were found in diabetic patients compared to standard response reported in non-diabetic patients.

scholarly journals Prescription of Antibiotic Prophylaxis for Dental Implant Surgery in Healthy Patients: A Systematic Review of Survey-Based Studies

2021 ◽  
Vol 11 ◽  
Author(s):  
Juan Carlos Bernabeu-Mira ◽  
Miguel Peñarrocha-Diago ◽  
David Peñarrocha-Oltra
Keyword(s):  
Systematic Review ◽  
Antibiotic Prophylaxis ◽  
Dental Implant ◽  
Response Rate ◽  
Scientific Evidence ◽  
Implant Failure ◽  
Implant Surgery ◽  
Systemic Antibiotic ◽  
Dental Implant Surgery ◽  
Systemic Antibiotic Prophylaxis

Background: Systemic antibiotic prophylaxis is frequently prescribed by dentists performing dental implant surgery to avoid premature implant failure and postoperative infections. The scientific literature suggests that a single preoperative dose suffices to reduce the risk of early dental implant failure in healthy patients.Material and Methods: A systematic review was made based on an electronic literature search in the PubMed-Medline, Embase, Web of Science, Scopus and Open Gray databases. The review addressed the question: “which antibiotic prophylaxis regimens are being used in dental implant surgery in healthy patients according to survey-based studies?” The identification, screening, eligibility and inclusion phases were conducted according to the PRISMA statement by two independent reviewers. The following data were collected: country, number of surveyed dentists, number of dentists who responded (n), response rate, routine prescription of antibiotic prophylactic treatment (yes, no, or conditioned prescription), prescription regimen (preoperative, perioperative or postoperative) and antibiotic choice (first and second choice). Cohen’s kappa coefficient (k) evaluated the level of agreement between the two reviewers. The analysis of risk of bias was performed follow the Joanna Briggs Institute checklist for observational studies. A descriptive statistical analysis was performed to calculate total target sample, sample size and total mean.Results: A total of 159 articles were identified, of which 12 were included in the analysis. Two thousand and seventy-seven dentists from nine different countries on three continents were surveyed. The median response rate was low and disparate between studies. About three-quarters of the surveyed dentists claimed to routinely prescribe systemic antibiotic prophylaxis for dental implant surgery. The prescription regimen was perioperative, postoperative and preoperative, in decreasing order of frequency. The most frequent first choice drug was amoxicillin, with amoxicillin-clavulanic acid as second choice.Conclusions: A majority of dentists from different countries do not prescribe systemic antibiotic prophylaxis for dental implant surgery following the available scientific evidence and could be overprescribing. Efforts are needed by dental educators and professionals to reduce the gap between the use of antibiotic prophylaxis for dental implant surgery as supported by the scientific evidence and what is being done by clinicians in actual practice.

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