Meta-analysis of the success rate of heartbeat recovery in patients with prehospital cardiac arrest in the past 40 years in China

Abstract. The ego depletion effect has been examined by over 300 independent studies during the past two decades. Despite its pervasive influence, recently this effect has been severely challenged and asserted to be a fake. Based on an up-to-date meta-analysis that examined the effectiveness of each frequently used depleting task, we preregistered the current experiment with the aim to examine whether there would be an ego depletion effect when the Stroop task is used as the depleting task. The results demonstrated a significant ego depletion effect. The current research highlights the importance of the depleting task’s effectiveness. That is to say, the “ego” could be “depleted,” but only when initial exertion is “depleting.”

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Faculty of 1000 evaluation for Anti-arrhythmia drugs for cardiac arrest: a systemic review and meta-analysis.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.718074102.793483920 ◽

2013 ◽

Author(s):

Jan Amlie

Keyword(s):

Cardiac Arrest ◽

Meta Analysis ◽

Systemic Review

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Comprehensive Analysis of Success Rate, Complications, Cost and Quality of Life Of Totally Implantable Venous-Access Ports: A Systematic Review and Meta-Analysis of Malignancy Populations from 21 Randomized Controlled Trials

SSRN Electronic Journal ◽

10.2139/ssrn.3562484 ◽

2020 ◽

Author(s):

Linghong Guo ◽

Ting Liu ◽

Shuang Dai ◽

Wen Guo ◽

Ting Zhang ◽

...

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Randomized Controlled Trials ◽

Success Rate ◽

Meta Analysis ◽

Venous Access ◽

Comprehensive Analysis ◽

Controlled Trials ◽

Randomized Controlled

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Pre-Procedural Lumbar Neuraxial Ultrasound—A Systematic Review of Randomized Controlled Trials and Meta-Analysis

Healthcare ◽

10.3390/healthcare9040479 ◽

2021 ◽

Vol 9 (4) ◽

pp. 479

Author(s):

Tatiana Sidiropoulou ◽

Kalliopi Christodoulaki ◽

Charalampos Siristatidis

Keyword(s):

Systematic Review ◽

Lumbar Spine ◽

Randomized Controlled Trials ◽

Success Rate ◽

Meta Analysis ◽

Controlled Trials ◽

Technical Failure ◽

Obese Patients ◽

Randomized Controlled ◽

Meta Analyses

A pre-procedural ultrasound of the lumbar spine is frequently used to facilitate neuraxial procedures. The aim of this review is to examine the evidence sustaining the utilization of pre-procedural neuraxial ultrasound compared to conventional methods. We perform a systematic review of randomized controlled trials with meta-analyses. We search the electronic databases Medline, Cochrane Central, Science Direct and Scopus up to 1 June 2019. We include trials comparing a pre-procedural lumbar spine ultrasound to a non-ultrasound-assisted method. The primary endpoints are technical failure rate, first-attempt success rate, number of needle redirections and procedure time. We retrieve 32 trials (3439 patients) comparing pre-procedural lumbar ultrasounds to palpations for neuraxial procedures in various clinical settings. Pre-procedural ultrasounds decrease the overall risk of technical failure (Risk Ratio (RR) 0.69 (99% CI, 0.43 to 1.10), p = 0.04) but not in obese and difficult spinal patients (RR 0.53, p = 0.06) and increase the first-attempt success rate (RR 1.5 (99% CI, 1.22 to 1.86), p < 0.0001, NNT = 5). In difficult spines and obese patients, the RR is 1.84 (99% CI, 1.44 to 2.3; p < 0.0001, NNT = 3). The number of needle redirections is lower with pre-procedural ultrasounds (SMD = −0.55 (99% CI, −0.81 to −0.29), p < 0.0001), as is the case in difficult spines and obese patients (SMD = −0.85 (99% CI, −1.08 to −0.61), p < 0.0001). No differences are observed in procedural times. Ιn conclusion, a pre-procedural ultrasound provides significant benefit in terms of technical failure, number of needle redirections and first attempt-success rate. Τhe effect of pre-procedural ultrasound scanning of the lumbar spine is more significant in a subgroup analysis of difficult spines and obese patients.

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Does Neonatal Imitation Exist? Insights From a Meta-Analysis of 336 Effect Sizes

Perspectives on Psychological Science ◽

10.1177/1745691620959834 ◽

2021 ◽

pp. 174569162095983

Author(s):

Jacqueline Davis ◽

Jonathan Redshaw ◽

Thomas Suddendorf ◽

Mark Nielsen ◽

Siobhan Kennedy-Costantini ◽

...

Keyword(s):

Social Behavior ◽

Positive Result ◽

Human Development ◽

Degrees Of Freedom ◽

Meta Analysis ◽

Effect Sizes ◽

Significant Evidence ◽

The Past ◽

Substantial Heterogeneity

Neonatal imitation is a cornerstone in many theoretical accounts of human development and social behavior, yet its existence has been debated for the past 40 years. To examine possible explanations for the inconsistent findings in this body of research, we conducted a multilevel meta-analysis synthesizing 336 effect sizes from 33 independent samples of human newborns, reported in 26 articles. The meta-analysis found significant evidence for neonatal imitation ( d = 0.68, 95% CI = [0.39, 0.96], p < .001) but substantial heterogeneity between study estimates. This heterogeneity was not explained by any of 13 methodological moderators identified by previous reviews, but it was associated with researcher affiliation, test of moderators ( QM) (15) = 57.09, p < .001. There are at least two possible explanations for these results: (a) Neonatal imitation exists and its detection varies as a function of uncaptured methodological factors common to a limited set of studies, and (2) neonatal imitation does not exist and the overall positive result is an artifact of high researcher degrees of freedom.

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Intraosseous versus intravenous vascular access during cardiopulmonary resuscitation for out-of-hospital cardiac arrest: a systematic review and meta-analysis of observational studies

Scandinavian Journal of Trauma Resuscitation and Emergency Medicine ◽

10.1186/s13049-021-00858-6 ◽

2021 ◽

Vol 29 (1) ◽

Author(s):

Yu-Lin Hsieh ◽

Meng-Che Wu ◽

Jon Wolfshohl ◽

James d’Etienne ◽

Chien-Hua Huang ◽

...

Keyword(s):

Cardiac Arrest ◽

Cardiopulmonary Resuscitation ◽

Hospital Discharge ◽

Vascular Access ◽

Subgroup Analysis ◽

Observational Studies ◽

Primary Outcome ◽

Meta Analysis ◽

Cochrane Library ◽

Hospital Cardiac Arrest

Abstract Introduction This study is aimed to investigate the association of intraosseous (IO) versus intravenous (IV) route during cardiopulmonary resuscitation (CPR) with outcomes after out-of-hospital cardiac arrest (OHCA). Methods We systematically searched PubMed, Embase, Cochrane Library and Web of Science from the database inception through April 2020. Our search strings included designed keywords for two concepts, i.e. vascular access and cardiac arrest. There were no limitations implemented in the search strategy. We selected studies comparing IO versus IV access in neurological or survival outcomes after OHCA. Favourable neurological outcome at hospital discharge was pre-specified as the primary outcome. We pooled the effect estimates in random-effects models and quantified the heterogeneity by the I2 statistics. Time to intervention, defined as time interval from call for emergency medical services to establishing vascular access or administering medications, was hypothesized to be a potential outcome moderator and examined in subgroup analysis with meta-regression. Results Nine retrospective observational studies involving 111,746 adult OHCA patients were included. Most studies were rated as high quality according to Newcastle-Ottawa Scale. The pooled results demonstrated no significant association between types of vascular access and the primary outcome (odds ratio [OR], 0.60; 95% confidence interval [CI], 0.27–1.33; I2, 95%). In subgroup analysis, time to intervention was noted to be positively associated with the pooled OR of achieving the primary outcome (OR: 3.95, 95% CI, 1.42–11.02, p: 0.02). That is, when the studies not accounting for the variable of “time to intervention” in the statistical analysis were pooled together, the meta-analytic results between IO access and favourable outcomes would be biased toward inverse association. No obvious publication bias was detected by the funnel plot. Conclusions The meta-analysis revealed no significant association between types of vascular access and neurological outcomes at hospital discharge among OHCA patients. Time to intervention was identified to be an important outcome moderator in this meta-analysis of observation studies. These results call for the need for future clinical trials to investigate the unbiased effect of IO use on OHCA CPR.

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165 A Review of The Current Literature on LMWH Administered at Different Times in Relation to MOS (Major Orthopaedic Surgery): Assessment of The Safety and Efficacy of The Different Proposed Strategies

British Journal of Surgery ◽

10.1093/bjs/znab134.190 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

G Placella ◽

V Pace ◽

P Antinolfi ◽

V Salini

Keyword(s):

Meta Analysis ◽

Convincing Evidence ◽

Just In Time ◽

Medical Complications ◽

Randomized Controlled ◽

The Past ◽

Cochrane Database ◽

Major Orthopedic Surgery ◽

Major Orthopaedic Surgery ◽

The One

Abstract Nowadays venous VTE represents an important perioperative and postoperative complication in patients undergoing elective Major Orthopedic Surgery (MOS). There are significant discrepancies between clinical practice, international recommendations, and published guidelines. Although thromboembolic events may be less common these days than in the past, they can still lead to serious medical complications. Therefore, most patients undergoing MOS procedures are provided with one of the thromboprophylactic treatments. The optimum timing of LMWH administrations remains debated. Customized structured electronic searches in PubMed and Cochrane database. Meta-Analysis, Randomized Controlled Trials, Systematic Reviews on different strategies of the use of LMWH for MOS. Studies on prophylactic regimens showed that subcutaneous LMWH plays a key role in the management of thromboprophylaxis in MOS. However, some controversies still stand. Among those most relevant, it remains unclear whether to start thromboprophylaxis before or after MOS to better balance the risks of clotting and bleeding. With regards to different times of LMWH administration, there is no convincing evidence that starting prophylaxis 12 hours preoperatively is associated with lower risks of VTE compared to prophylaxis started 12 to 24 hours postoperatively. Furthermore, it seems that the most safe and efficient LMWH regimen is the one called “Just-in-time” (LMWH started 6 hours post-op).

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447 What Age is Best to Perform Myringoplasty?

British Journal of Surgery ◽

10.1093/bjs/znab134.556 ◽

2021 ◽

Vol 108 (Supplement_2) ◽

Author(s):

L Wilks ◽

R Mcleod ◽

V Unadkat

Keyword(s):

Systematic Review ◽

Success Rate ◽

Meta Analysis ◽

Paediatric Population ◽

Cochrane Library ◽

Clear Correlation ◽

Success Rates ◽

Prisma Statement ◽

Transitional Point ◽

The Cochrane Library

Abstract Aim This systematic review and meta-analysis aims to assess this relationship and determine the most appropriate age for recommendation of surgery. Method According to the “Preferred Reporting items for systematic review and meta-analysis” (PRISMA) statement, a literature search was performed across Medline, EMBASE and the Cochrane library from 1946-2018. Articles examining a relationship between age and myringoplasty or type 1 tympanoplasty success rates were screened. Results 20 articles encompassing data from 2244 procedures were included. The overall results conveyed a clear correlation between increasing age and rising success rate. A t-test was conducted which demonstrated a significant (P = 0.05) transition at aged 10, whereby success rate below age 10 was 70.6% and above 10 was 86%. Conclusions This systematic review and meta-analysis has uncovered a clear correlation between increasing age and increasing success rate for myringoplasty in the paediatric population. Furthermore, a significant transitional point has been demonstrated at the age of 10 and We hope that knowledge of increased success rates particularly after the age of 10 helps clinicians make more informed decisions about when to operate

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