scholarly journals Impact of simultaneous placement of implant and block bone graft substitute: an in vivo peri-implant defect model

2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Minh Khai Le Thieu ◽  
Amin Homayouni ◽  
Lena Ringsby Hæren ◽  
Hanna Tiainen ◽  
Anders Verket ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Bone Graft Substitute ◽  
Healing Time ◽  
Implant Surface ◽  
Implant Placement ◽  
Bone Fraction ◽  
Bone To Implant Contact ◽  
Implant Treatment ◽  
Bone Dimensions

Abstract Background Insufficient bone volume around an implant is a common obstacle when dental implant treatment is considered. Limited vertical or horizontal bone dimensions may lead to exposed implant threads following placement or a gap between the bone and implant. This is often addressed by bone augmentation procedures prior to or at the time of implant placement. This study evaluated bone healing when a synthetic TiO2 block scaffold was placed in circumferential peri-implant defects with buccal fenestrations. Methods The mandibular premolars were extracted and the alveolar bone left to heal for 4 weeks prior to implant placement in six minipigs. Two cylindrical defects were created in each hemi-mandible and were subsequent to implant placement allocated to treatment with either TiO2 scaffold or sham in a split mouth design. After 12 weeks of healing time, the samples were harvested. Microcomputed tomography (MicroCT) was used to investigate defect fill and integrity of the block scaffold. Distances from implant to bone in vertical and horizontal directions, percentage of bone to implant contact and defect fill were analysed by histology. Results MicroCT analysis demonstrated no differences between the groups for defect fill. Three of twelve scaffolds were partly fractured. At the buccal sites, histomorphometric analysis demonstrated higher bone fraction, higher percentage bone to implant contact and shorter distance from implant top to bone 0.5 mm lateral to implant surface in sham group as compared to the TiO2 group. Conclusions This study demonstrated less bone formation with the use of TiO2 scaffold block in combination with implant placement in cylindrical defects with buccal bone fenestrations, as compared to sham sites.

Human Histologic Evaluation of a Six-year-old Threaded Implant Retrieved from a Subject with Osteoporosis

2008 ◽  
Vol 9 (3) ◽  
pp. 99-105 ◽  
Author(s):  
Adriano Piattelli ◽  
Jamil A. Shibli ◽  
Leandro de Melo ◽  
Giovanna Lezzi ◽  
Susana d'Avila ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Close Contact ◽  
Human Life ◽  
Elderly Subjects ◽  
Implant Surface ◽  
Implant Placement ◽  
Histologic Evaluation ◽  
Bone To Implant Contact ◽  
The Mean ◽  
Cement Lines

Abstract Aim The aim of this case report was to present the evaluation of the bone-to-implant contact in an implant retrieved from a subject with osteoporosis after six years of load. Background Systemic conditions associated with osteoporosis have been postulated to contribute to the severity of alveolar bone loss. The increase in human life expectancy, the increased number of elderly subjects who are partially or totally edentulous, and the use of dental implants for oral habilitation in subjects with osteoporosis has raised several questions. Report A 68-year-old woman with postmenopausal osteoporosis received a prosthetic evaluation of an implant-supported restoration. Histologically, the peri-implant bone appeared healthy. The peri-implant bone appeared in close contact with the implant surface, whereas marrow spaces could be detected in other areas along with prominently stained cement lines. The mean of bone-to-implant contact was 62.51±1.96. Conclusion The results of the evaluation of the dental implant reported here suggest the presence of osteoporosis may not be a contra-indication for implant placement at least after osseointegration has already been established. Citation de Melo L, Piattelli A, Lezzi G, d'Avila S, Zenóbio EG, Shibli JA. Human Histologic Evaluation of a Six-year-old Threaded Implant Retrieved from a Subject with Osteoporosis. J Contemp Dent Pract 2008 March; (9)3:099-105.

Calcium Phosphate-Coated Titanium Implants in the Mandible: Limitations of the in vivo Minipig Model

2020 ◽  
Vol 61 (6) ◽  
pp. 177-187
Author(s):  
Till Kämmerer ◽  
Tony Lesmeister ◽  
Victor Palarie ◽  
Eik Schiegnitz ◽  
Andrea Schröter ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Statistical Difference ◽  
Surface Modifications ◽  
Titanium Implants ◽  
In Vivo Model ◽  
Implant Surface ◽  
Press Fit ◽  
Endosseous Implant ◽  
Bone To Implant Contact

Introduction: We aimed to compare implant osseointegration with calcium phosphate (CaP) surfaces and rough subtractive-treated sandblasted/acid etched surfaces (SA) in an in vivo minipig mandible model. Materials and Methods: A total of 36 cylindrical press-fit implants with two different surfaces (CaP, n = 18; SA, n = 18) were inserted bilaterally into the mandible of 9 adult female minipigs. After 2, 4, and 8 weeks, we analyzed the cortical bone-to-implant contact (cBIC; %) and area coverage of bone-to-implant contact within representative bone chambers (aBIC; %). Results: After 2 weeks, CaP implants showed no significant increase in cBIC and aBIC compared to SA (cBIC: mean 38 ± 5 vs. 16 ± 11%; aBIC: mean 21 ± 1 vs. 6 ± 9%). Two CaP implants failed to achieve osseointegration. After 4 weeks, no statistical difference between CaP and SA was seen for cBIC (mean 54 ± 15 vs. 43 ± 16%) and aBIC (mean 43 ± 28 vs. 32 ± 6). However, we excluded two implants in each group due to failure of osseointegration. After 8 weeks, we observed no significant intergroup differences (cBIC: 18 ± 9 vs. 18 ± 20%; aBIC: 13 ± 8 vs. 16 ± 9%). Again, three CaP implants and two SA implants had to be excluded due to failure of osseointegration. Conclusion: Due to multiple implant losses, we cannot recommend the oral mandibular minipig in vivo model for future endosseous implant research. Considering the higher rate of osseointegration failure, CaP coatings may provide an alternative to common subtractive implant surface modifications in the early phase post-insertion.

scholarly journals Immediate Implant Placement in Infected Sockets: A Consecutive Cohort Study

2020 ◽  
Vol 11 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Ashish Kakar ◽  
Kanupriya Kakar ◽  
Minas D. Leventis ◽  
Gaurav Jain
Keyword(s):  
Bone Graft ◽  
Clinical Results ◽  
Bone Graft Substitute ◽  
Graft Material ◽  
Success Rates ◽  
Implant Surface ◽  
Implant Placement ◽  
Immediate Placement ◽  
Immediate Implant

Introduction: Immediate placement of implants in a fresh post-extraction socket is an increasingly popular and established treatment option. However, active infection in the extraction site may adversely affect the outcome of this procedure. This study was designed to assess the clinical results of immediate placement of dental implants in infected extraction sockets using a standardized protocol, which included (a) the use of an Er,Cr:YSGG laser for the decontamination of the infected socket prior to implant insertion, and (b) the utilization of an in situ hardening alloplastic bone graft substitute to augment the gap between the implant surface and the labial plate of bone. Patients and Methods: A retrospective record review was used to identify 68 patients who had implants placed as per the described protocol. A total of 126 implants were placed in 68 patients (65 implants in the maxilla, 61 implants in the mandible). The implants were loaded 136 ± 73 days (mean ± standard deviation; range: 37–400 days) after implant placement. Eight patients (16 implants) were subsequently lost to follow up. Results: 105 of the 110 implants (95.45%) placed immediately in the infected sites using the described protocol survived after prosthetic loading. Conclusion: Immediate implant placement in previously infected sites using the protocols mentioned in our study with laser decontamination of the socket, grafting with an in situ hardening alloplastic bone graft material and non-submerged healing shows a similar survival rate to the published success rates for immediate implants placed in non-infected sites.

scholarly journals In vivo intraosseous temperature during implant placement‐ the influence of the drilling protocol, implant surface and surface lubrication: A study in sheep

2019 ◽  
Vol 30 (S19) ◽  
pp. 103-103
Author(s):  
Yohei Jinno ◽  
Michele Stocchero ◽  
Marco Toia ◽  
Marianne Ahmad ◽  
Tomas Albrektsson ◽  
...  
Keyword(s):  
Implant Surface ◽  
Implant Placement

scholarly journals Intraosseous Temperature Change during Installation of Dental Implants with Two Different Surfaces and Different Drilling Protocols: An In Vivo Study in Sheep

2019 ◽  
Vol 8 (8) ◽  
pp. 1198 ◽  
Author(s):  
Michele Stocchero ◽  
Yohei Jinno ◽  
Marco Toia ◽  
Marianne Ahmad ◽  
Evaggelia Papia ◽  
...  
Keyword(s):  
Temperature Increase ◽  
Element Model ◽  
Multiple Regression Model ◽  
Metatarsal Bone ◽  
Area Fraction ◽  
Bone Area ◽  
Implant Surface ◽  
Bone Necrosis ◽  
Bone To Implant Contact

Background: The intraosseous temperature during implant installation has never been evaluated in an in vivo controlled setup. The aims were to investigate the influence of a drilling protocol and implant surface on the intraosseous temperature during implant installation, to evaluate the influence of temperature increase on osseointegration and to calculate the heat distribution in cortical bone. Methods: Forty Brånemark implants were installed into the metatarsal bone of Finnish Dorset crossbred sheep according to two different drilling protocols (undersized/non-undersized) and two surfaces (moderately rough/turned). The intraosseous temperature was recorded, and Finite Element Model (FEM) was generated to understand the thermal behavior. Non-decalcified histology was carried out after five weeks of healing. The following osseointegration parameters were calculated: Bone-to-implant contact (BIC), Bone Area Fraction Occupancy (BAFO), and Bone Area Fraction Occupancy up to 1.5 mm (BA1.5). A multiple regression model was used to identify the influencing variables on the histomorphometric parameters. Results: The temperature was affected by the drilling protocol, while no influence was demonstrated by the implant surface. BIC was positively influenced by the undersized drilling protocol and rough surface, BAFO was negatively influenced by the temperature rise, and BA1.5 was negatively influenced by the undersized drilling protocol. FEM showed that the temperature at the implant interface might exceed the limit for bone necrosis. Conclusion: The intraosseous temperature is greatly increased by an undersized drilling protocol but not from the implant surface. The temperature increase negatively affects the bone healing in the proximity of the implant. The undersized drilling protocol for Brånemark implant systems increases the amount of bone at the interface, but it negatively impacts the bone far from the implant.

scholarly journals The Effect of Hydroxyapatite Nanocrystals on Osseointegration of Titanium Implants: AnIn VivoRabbit Study

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Karin Breding ◽  
Ryo Jimbo ◽  
Mariko Hayashi ◽  
Ying Xue ◽  
Kamal Mustafa ◽  
...  
Keyword(s):  
Surface Chemistry ◽  
Calcium Phosphates ◽  
Surface Characteristics ◽  
Healing Time ◽  
Titanium Implants ◽  
Pcr Analysis ◽  
Rt Pcr ◽  
Implant Surface ◽  
Hydroxyapatite Nanocrystals

Osseointegration is dependent on implant surface characteristics, including surface chemistry and topography. The presence of nanosized calcium phosphates on the implant surface is interesting to investigate since they affect both the nanotopography and surface chemistry, forming a bone mineral resembling surface. In this work, the osseointegration of titanium implants with and without the presence of hydroxyapatite (HA) nanocrystals has been evaluatedin vivo. The integration was examined using removal torque measurements and real-time polymerase chain reaction (RT-PCR) analysis. The study was performed using two healing time points, 3 and 12 weeks. The results showed that the torque needed to remove the implants was insignificant between the non- and HA-coated implants, both at weeks 3 and 12. The RT-PCR, however, showed significant differences for osteoblast, osteoclast, and proinflammation markers when HA nanocrystals were present.

Impact of Smoking on Human Bone Apposition at Different Dental Implant Surfaces: A Histologic Study in Type IV Bone

2010 ◽  
Vol 36 (2) ◽  
pp. 85-90 ◽  
Author(s):  
Susana d'Avila ◽  
Leonardo Delfino dos Reis ◽  
Adriano Piattelli ◽  
Kelly C. S. Aguiar ◽  
Marcelo de Faveri ◽  
...  
Keyword(s):  
Healing Time ◽  
Machined Surface ◽  
Implant Surface ◽  
Bone Apposition ◽  
Type Iv ◽  
Posterior Maxilla ◽  
Bone To Implant Contact ◽  
The Mean ◽  
Edentulous Patients ◽  
Etched Surface

Abstract Smoking has adverse effects on peri-implant bone healing and can cause bone loss around successfully integrated implants placed on type IV bone. This study evaluated the influence of implant surface topography of microimplants retrieved from posterior maxilla of smokers after 2 months of unloaded healing. Seven partially edentulous patients received 2 microimplants (machined and sandblasted acid-etched surface) each during conventional implant surgery. Histometric evaluation showed that the mean bone to implant contact was 10.40 ± 14.16% and 22.19 ± 14.68% to machined and sandblasted acid-etched surfaces, respectively (P < .001). These data suggest that the sandblasted acid-etched surface presented better results than the machined surface after a short healing time in smokers.

scholarly journals CBCT ANALYSIS OF ALVEOLAR BONE DIMENSIONS IN MANDIBULAR POSTERIOR TEETH: A PRELIMINARY STUDY

2019 ◽  
pp. 1-3
Author(s):  
cristalle Soman* ◽  
Alanoud Almuhrij ◽  
Alghusen Alghusen ◽  
Faizal Abdulrahman Alsubaie ◽  
Manal Aljamal ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Statistical Significance ◽  
Mandibular Canal ◽  
Success Rates ◽  
Posterior Teeth ◽  
Implant Placement ◽  
Immediate Implant ◽  
Preliminary Study ◽  
Mandibular Posterior Teeth ◽  
Bone Dimensions

OBJECTIVES: Extraction of mandibular posterior teeth followed by immediate implant placement is considered as an optimal technique of immediate prosthetic rehabilitation. The analysis of alveolar bone dimensions with Cone Beam Computerized Tomography prior to implant placement is a prime determinant in treatment planning. Hence this preliminary study was conducted to analyze the alveolar bone dimensions in dentate mandibular posterior teeth to evaluate the available bone which can be utilized for immediate implant placements. MATERIALS AND METHODS: Retrospective data of 200 cases of full volume CBCT was procured from Riyadh Elm University (REU) database and reviewed for eligibility. Atotal of 10 cases were included in the study. Scans were assessed for thickness of buccal and lingual walls at 4mm below the CEJ (MP1) and at midroot level (MP2). Alveolar width was assessed at most coronal point on alveolar bone (BW1) and at superior border of mandibular canal (BW2). The height was be calculated by measuring the vertical distance between BW1 and BW2. Data was tabulated and statistically analyzed using unpaired t-test. RESULTS: The results of our study indicates that dimensions of buccal and lingual bone walls of all teeth at MP1 and MP2 in PM1, PM2 and M1 were statistically significant. Also only the 1st premolar (PM1) showed statistical significance with regard to dimensions at BW1 and BW2. CONCLUSION: The present study highlights the need for further studies with larger samples which can impact the immediate implant success rates in mandibular posterior teeth.

scholarly journals Defining surfaces : Implant topography – a review (Preprint)

2018 ◽  
Author(s):  
Preeti Satheesh Kumar ◽  
Vyoma Venkatesh Grandhi ◽  
Vrinda Gupta
Keyword(s):  
Surface Roughness ◽  
Surface Topography ◽  
Dental Implants ◽  
Sol Gel ◽  
Implant Surface ◽  
Research Publications ◽  
Bone To Implant Contact ◽  
Titanium Dental Implants

BACKGROUND . A variety of claims are made regarding the effects of surface topography on implant osseointegration. The development of implant surfaces topography has been empirical, requiring numerous in vitro and in vivo tests. Most of these tests were not standardized, using different surfaces, cell populations or animal models. The exact role of surface chemistry and topography on the early events of the osseointegration of dental implants remain poorly understood. OBJECTIVE This review considers the major claims made concerning the effects of titanium implant surface topography on osseointegration. The osseointegration rate of titanium dental implants is related to their composition and surface roughness. The different methods used for increasing surface roughness or applying osteoconductive coatings to titanium dental implants are reviewed. Important findings of consensus are highlighted, and existing controversies are revealed. METHODS This review considers many of the research publications listed in MEDLINE and presented in biomedical research publications and textbooks. Surface treatments, such as titanium plasma-spraying, grit-blasting acid-etching,alkaline etching, anodization,polymer demixing ,sol gel conversion and their corresponding surface morphologies and properties are described. RESULTS Many in vitro evaluations are not predictive of or correlated with in vivo outcomes. In some culture models, increased surface topography positively affects pro-osteogenic cellular activities. Many studies reveal increase in bone-to-implant contact,with increased surface topography modifications on implant surfaces. CONCLUSIONS Increased implant surface topography improves the bone-to-implant contact and the mechanical properties of the enhanced interface.

scholarly journals Full Mouth Rehabilitation with Implant-Supported Prostheses for Severe Periodontitis: A Case Report

2010 ◽  
Vol 4 (1) ◽  
pp. 165-171 ◽  
Author(s):  
Sompop Bencharit ◽  
Debra Schardt-Sacco ◽  
Michael B Border ◽  
Colin P Barbaro
Keyword(s):  
Dental Implants ◽  
Bone Grafting ◽  
Alveolar Bone ◽  
Primary Stability ◽  
Healing Time ◽  
Oral Rehabilitation ◽  
Implant Placement ◽  
Periodontal Inflammation ◽  
Severe Periodontitis ◽  
Full Mouth Rehabilitation

Oral rehabilitation for a patient with severe loss of alveolar bone and soft tissue resulting from severe periodontitis presents a challenge to clinicians. Replacing loosening natural teeth with fixed prostheses supported by dental implants often requires either gingival surgery or bone grafting. The outcome of the bone grafting is sometimes unpredictable and requires longer healing time and/ or multiple surgeries. The presence of periodontal inflammation and periapical lesions often delay the placement of bone grafts as well as dental implants. Here we present a clinical case of a patient undergone full mouth reconstruction with implant-supported fixed prostheses. We demonstrated that early placement of implants (three weeks after extractions) with minimal bone grafting may be an alternative to conventional bone grafting followed by implant placement. We believe that primary stability during implant placement may contribute to our success. In addition, composite resin gingival material may be indicated in cases of large fixed implant prostheses as an alternative to pink porcelain.

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