scholarly journals Suicide by ethylene glycol/brake oil poisoning—a case report

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Amal Nishantha Vadysinghe ◽  
W. G. G. B. Kumarasinghe ◽  
Sarathchandra Kodikara ◽  
Navoda Wickramasinghe
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Ethylene Glycol ◽  
Cardiovascular Complications ◽  
Severe Renal Failure ◽  
Manner Of Death ◽  
Brake Fluid ◽  
Fluid Ingestion ◽  
Forensic Practice ◽  
Corrosive Effect

Abstract Background Brake fluid is used for automobiles. It is a mixture of different glycol derivatives including ethylene glycol and diethylene glycol (DEG) which are metabolized into various toxic metabolites. Fatalities following brake fluid ingestion are rare in forensic practice. Here, we report a case of suicide by brake fluid ingestion complicated with severe renal failure and esophageal and gastric erosions. Case presentation A 52-year-old male, with a history of alcohol dependence and comorbid moderate depression, ingested a bottle of brake fluid (100ml) mixed with alcohol. He had defaulted psychiatric follow-up. He developed severe metabolic acidosis and acute renal failure which necessitated intensive care, other supportive management, and the antidote; ethyl alcohol. On the 2nd day of admission, he developed upper gastrointestinal bleeding with melena. He also had seizures and cardiovascular complications. He died 12 days after hospital admission, and the manner of death was concluded as suicidal. The autopsy revealed congested and edematous brain, flabby and pale heart without evidence of infarction, erythematous trachea, bilateral diffuse pulmonary edema, congested liver, ulcer over the lower 1/3 of the esophagus, and few ulcers in the stomach. Also, the kidneys were edematous, diffusely necrosed, and there were adrenal hemorrhages. Conclusions This case report highlights the severity of effects of brake fluid poisoning including the corrosive effect on gastrointestinal mucosa which is rarely encountered in clinical practice.

scholarly journals Ethylene glycol intoxication following brake fluid ingestion complicated with unilateral facial nerve palsy: a case report

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
B. M. D. B. Basnayake ◽  
A. W. M. Wazil ◽  
N. Nanayakkara ◽  
R. M. B. S. S. Mahanama ◽  
P. N. S. Premathilake ◽  
...  
Keyword(s):  
Case Report ◽  
Ethylene Glycol ◽  
Facial Nerve ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Brake Fluid ◽  
Fluid Ingestion ◽  
Ethylene Glycol Intoxication

Use of immunostippressive drugs and lamivudine in a patient with nephrotic syndrome, severe renal failure, and HBV cirrhosis: Case report

2003 ◽  
Vol 20 (4) ◽  
pp. 191-194 ◽  
Author(s):  
Mustafa Balal ◽  
Neslihan Seyrek ◽  
Ibrahim Karayaylali ◽  
Saime Paydas ◽  
Gulfiliz Gonlusen
Keyword(s):  
Renal Failure ◽  
Nephrotic Syndrome ◽  
Case Report ◽  
Severe Renal Failure

scholarly journals Dialysis Dependent 'Double Positive Disease' Responding To Immunosuppression: A Case Report

2016 ◽  
Vol 06 (02) ◽  
pp. 076-078
Author(s):  
Shashidhar Baikunje ◽  
Mahesha Vankalakunti ◽  
Adithi Bhandary ◽  
P.S. Prakash
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Case Report ◽  
Initial Data ◽  
Plasma Exchange ◽  
Renal Outcome ◽  
Double Positive ◽  
Severe Renal Failure ◽  
Favorable Prognosis

AbstractThe outcome of patients with crescentic nephritis and the presence of both ANCA and anti GBM disease (double positive disease) is controversial. Initial data supported the view that this condition has a more favorable prognosis than anti GBM disease but larger and more recent series found much worse renal outcome especially in patients with severe renal failure requiring dialysis. We present a case with severe renal failure due to double positive disease who recovered renal function with aggressive immunosuppression including steroids, cyclophosphamide and plasma exchange.

scholarly journals Ceftriaxone-induced hemolytic anemia with severe renal failure: a case report and review of literature

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Hans Benno Leicht ◽  
Elke Weinig ◽  
Beate Mayer ◽  
Johannes Viebahn ◽  
Andreas Geier ◽  
...  
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Hemolytic Anemia ◽  
Review Of Literature ◽  
Severe Renal Failure

scholarly journals Smoke on the water: A case report of chronic renal failure resulting from the ingestion of smoke machine fluid

2016 ◽  
Vol 18 (1) ◽  
pp. 57-58
Author(s):  
Alice Trimble ◽  
Richard Partridge
Keyword(s):  
Chronic Kidney Disease ◽  
Intensive Care Unit ◽  
Renal Failure ◽  
Ethylene Glycol ◽  
Information Service ◽  
Fluid Ingestion ◽  
Internal Review ◽  
The Subject ◽  
Oxalate Nephropathy ◽  
Poisons Information

We report the case of an 18-year-old male admitted to the Intensive Care Unit in Basingstoke and North Hampshire Hospital, who developed chronic kidney disease following the ingestion of smoke machine fluid. Smoke machine fluid may contain ethylene glycol, and a diagnosis of ethylene glycol toxicity with calcium oxalate nephropathy was made. This case resulted in a National Poisons Information Service internal review of the subject and a new TOXBASE entry for smoke machine fluid ingestion.

Platelet Function and the Bleeding Time in Progressive Renal Failure

1988 ◽  
Vol 60 (01) ◽  
pp. 083-087 ◽  
Author(s):  
M P Gordge ◽  
R W Faint ◽  
P B Rylance ◽  
G H Neild
Keyword(s):  
Renal Failure ◽  
Platelet Aggregation ◽  
Platelet Function ◽  
Bleeding Time ◽  
C Reactive Protein ◽  
Severe Renal Failure ◽  
Reactive Protein ◽  
Thromboxane Production ◽  
Von Willebrand ◽  
Willebrand Factor

SummaryBleeding time and platelet function tests were performed on 31 patients with progressive chronic renal failure (CRF) due to non-immunological (urological) causes, and compared with 22 healthy controls. Patients were classified as mild (plasma creatinine <300 μmol/l), moderate (300-600 μmol/l) or severe renal failure (>600 μmol/l). Bleeding time was rarely prolonged in mild and moderate CRF and mean bleeding time significantly elevated only in severe CRF (p <0.005). Haematocrit was the only index which correlated with bleeding time (r = -0.40). Platelet counts, collagen stimulated thromboxane generation, and platelet aggregation responses to ADP, collagen and ristocetin were all either normal or increased in all three CRF groups, but thromboxane production in clotting blood was reduced. Plasma fibrinogen, C reactive protein and von Willebrand factor (vWF) were elevated in proportion to CRF. We found no evidence that defects in platelet aggregation or platelet interaction with vWF prolong the bleeding time in patients with progressive CRF.

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