scholarly journals Transcranial direct current stimulation (tDCS): its effect on improving dysphagia in stroke patients

Author(s):  
Salah Abd Elmonem Sawan ◽  
Abdelazim M. Reda ◽  
Ahmed Hosny Kamel ◽  
Mennat Allah Mohamed Ali

Abstract Background Transcranial direct current stimulation (tDCS) may have a potential for improving post-stroke dysphagia. Objective The purpose of this study was to examine the effect of tDCS on improving dysphagia in stroke patients. Patients and methods Forty stroke patients were divided randomly into two equal groups (the study (group A) and control groups (group B). Group A received a physical therapy program and active (tDCS), and group B received the same physical therapy program and sham (tDCS). The Dysphagia Outcome and Severity Scale (DOSS) and videofluoroscopy were performed in all patients before and after 2 weeks of the treatment program. Results Before treatment, there were no significant differences between the two groups for DOSS score or digital fluoroscopic findings. After treatment, there were significant differences between the study and control group for DOSS score and digital fluoroscopic findings. Conclusion Anodal tDCS is effective in improving dysphagia in stroke patients.

2019 ◽  
Vol 60 ◽  
pp. 41-48 ◽  
Author(s):  
Shahram Ghorbani Behnam ◽  
Seyed Abbas Mousavi ◽  
Mohammad Hassan Emamian

AbstractBackground:Current treatments for smoking cessation are not effective for most smokers. This study aims to examine the effectiveness of transcranial Direct Current Stimulation (tDCS) on smoking cessation.Methods:In this randomized, sham-controlled trial study, tobacco-dependent (by DSM-5) male participants were recruited from the general public invitation. Participants were randomly allocated to 5 groups; (A), treatment with 300mg bupropion for 8 weeks; (B), active tDCS (20 sessions for 4 weeks); (C), sham for group B ; (D), active tDCS (20 sessions for 12 weeks), and (E), sham for group D. The electrode montage was anode F3 and cathode F4. Study outcomes include salivary cotinine, Fagerstrom test for nicotine dependence, and smoked cigarette per day, were examined on three time points. Repeated-measures analysis of variances and the generalized estimation equation (GEE) model were employed for data analysis.Results:Among 210 volunteers, 170 participants completed the study. Mean age of participants was 42.9 years, ranging from 21 to 64 years. The 6-month point abstinence rates in groups A, B and D were 20%, 7% and 25.7%, and in C, D sham groups were 3.1% and 3% respectively. Results of the GEE model showed that although group D was not different from group A in abstinence rate, i.e., salivary cotinine >4 (p = 0.266), nicotine dependency by Fagerstrom test was lower in this group compared to group A (p = 0.019).Conclusions:The 12-week tDCS had a clinically good therapeutic effect on smoking cessation and its dependency. It may be a substitute for bupropion treatment.


2021 ◽  
Vol 19 (2) ◽  
pp. 169-185
Author(s):  
Ewa Wilczek-Rużyczka ◽  
Aleksandra Gawrońska ◽  
Jolanta Góral-Półrola

The aim of the study was to answer the question as to whether transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome in nurses than the commonly used individual psychotherapy. The study included 40 nurses from various health care facilities located in the Lesser Poland and Podkarpackie Voivodeship suffering from burnout syndrome. They were assigned to the experimental group while 20 to the control group. Two different therapy models were used: the experimental group (A) included 20 of the nurses treated with the use of transcranial direct current stimulation (tDCS), four times a week for 8 weeks, in sessions that lasted initially 10, then 15, 20, 25 and finally 30 minutes and the control group (B) included 20 of the nurses treated with individual psychotherapy employed for 8 weeks, once a week for 30 minutes. To evaluate the results we used: screening with a clinical interview, the Mini–Mental State Examination (MMSE), the Beck Depression Inventory and a Polish adaptation of the Italian questionnaire created by Massimo Sentinello (LBQ). Treatment was provided. The transcranial direct current stimulation (tDCS) used in Group A is more effective in reducing many symptoms than is the case with individual psychotherapy. Comparing the intragroup effects, it was found that the tDCS employed in Group A significantly reduced the intensity of depressive symptoms among the surveyed nurses [F (1.38) = 57.62; p <0.001; η2 = 0.603] while the individual psychotherapy used in Group B failed to produce a statistically significant effect [F (1.38) = 1.794; p = 0.188; η2 = 0.045]. These include a reduction of depression, a reduction in chronic psychophysical exhaustion, vegetative problem reduction, and the improvement of nurse-patient relations. Neurotherapy with the use of transcranial direct current stimulation (tDCS) is more effective in reducing burnout syndrome than the commonly used individual psychotherapy. It also helps to return these nurses to full professional activity. The studies presented above recommend the use of new neurotechnologies in therapy as a result of their usefulness and non-invasive character.


2011 ◽  
Vol 25 (9) ◽  
pp. 838-846 ◽  
Author(s):  
Stefan Hesse ◽  
Andreas Waldner ◽  
Jan Mehrholz ◽  
Christopher Tomelleri ◽  
Michael Pohl ◽  
...  

Background. No rehabilitation intervention has effectively improved functional use of the arm and hand in patients with severe upper limb paresis after stroke. Pilot studies suggest the potential for transcranial direct current stimulation and bilateral robotic training to enhance gains. Objective. In a double-blind, randomized trial the combination of these interventions was tested. Methods. This study randomized 96 patients with an ischemic supratentorial lesion of 3 to 8 weeks’ duration with severe impairment of motor control with a Fugl-Meyer score (FMS) for the upper limb <18 into 3 groups. For 6 weeks, group A received anodal stimulation of the lesioned hemisphere, group B received cathodal stimulation of the nonlesioned side for 20 minutes at 2.0 mA, and group C received sham stimulation. The electrodes were placed over the hand area and above the contralateral orbit. Contemporaneously, the subjects practiced 400 repetitions each of 2 different bilateral movements on a robotic assistive device. Results. The groups were matched at onset. The FMS improved in all patients at 6 weeks ( P < .001). No between-group differences were found; initial versus finish FMS scores were 7.8 ± 3.8 versus 19.1 ± 14.4 in group A, 7.9 ± 3.4 versus 18.8 ± 10.5 in group B, and 8.2 ± 4.4 versus 19.2 ± 15.0 in group C. No significant changes between groups were present at 3 months. Conclusions. Neither anodal nor cathodal transcranial direct current stimulation enhanced the effect of bilateral arm training in this exploratory trial of patients with cortical involvement and severe weakness. Unilateral hand training and upregulation of the nonlesioned hemisphere might also be tried in this population.


Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e428-e429 ◽  
Author(s):  
S. Fujimoto ◽  
N. Kon ◽  
Y. Otaka ◽  
T. Yamaguchi ◽  
R. Osu ◽  
...  

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Pratik Y Chhatbar ◽  
Rong Chen ◽  
William DeVries ◽  
Ha M Lee ◽  
Mark S George ◽  
...  

Introduction: Positive dose-response relationship with the use of Transcranial direct current stimulation (tDCS) in post-stroke upper limb motor recovery demands investigating the efficacy of higher tDCS doses. Safety and tolerability of tDCS current higher than typically used 2 mA has not been investigated in stroke patients. Hypothesis: tDCS application up to 4 mA for 30 minutes is safe and tolerable in stroke patients Methods: A 3+3 study design with current escalation schedule of 1, 2, 2.5, 3, 3.5 and 4 mA was adopted for this tDCS safety study ( Fig. A ). Patients with first-ever ischemic stroke and unilateral hemiparesis were recruited. Single session of tDCS and customatory occupational therapy for 30 minutes using a device (Chattanooga Ionto) with 5х7 cm 2 sponge electrodes (Soterix Medical) on a bihemispheric montage (C3/C4, anode on lesional side) were administered. Stopping rules were (1) second degree scalp burn, or (2) seizure, or (3) new lesion(s) on DWI sequence of MRI or decreased ADC. Tolerability was assessed by tDCS questionnaire administered before and after tDCS. Body resistance and skin temperature at electrode contact site were monitored in real time. Results: Eighteen patients were enrolled and completed the study. The current was escalated to 4 mA without any major safety concerns (stopping rule). 50% of patients revealed transient skin redness at anodal site and 17% at cathodal side. No patient had any persistent skin perception issues at the end of tDCS ( Fig. B ). We also present real-time monitoring of body resistance and skin temperature to ensure safety during tDCS administration ( Fig. C ). Skin barrier remained intact through tDCS, as demonstrated by absence of abrupt decrease in body resistance (<400 Ω). Skin temperatures remained well below body temperature (range 26°C-35°C) Conclusion: Our data support that tDCS current up to 4 mA is safe and tolerable in ischemic stroke patients. Efficacy and safety should be further tested in a phase II study.


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