scholarly journals Multimodality imaging of an interventricular septum hydatid cyst

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Krishna Prasad ◽  
Rupesh Kumar ◽  
Vikram Halder ◽  
Muni Raju ◽  
Sunder Lal Negi ◽  
...  
Keyword(s):  
Poor Prognosis ◽  
Surgical Planning ◽  
Multimodality Imaging ◽  
Interventricular Septum ◽  
Pulmonary Angiography ◽  
Emission Tomography ◽  
Ct Pulmonary Angiography ◽  
Case Presentation ◽  
Positron Emission ◽  
Accidental Host

Abstract Background Cardiac hydatid over the interventricular septum is extremely rare. Echinococcus infests humans as an accidental host. Echocardiography usually clinches the diagnosis of cardiac hydatid. However, multimodality imaging including cardiac magnetic resonance (CMR) imaging, computed tomography (CT), and positron emission tomography (PET) helps in supporting the diagnosis and surgical planning. Case presentation We present a 29-year-old male who presented with dyspnea and was found to have cardiac hydatid on the interventricular septum on echocardiography. CT and CMR clinched the diagnosis. CT pulmonary angiography showed extensive pulmonary thromboembolization and cavitary consolidation in lungs. PET showed no active uptake in cardiac hydatid. Post-surgical enucleation of the cyst his hypotension worsened and succumbed. Conclusion Cardiac hydatid has poor prognosis. Multimodality imaging helps in confirming the diagnosis and surgical planning.

scholarly journals Case Report: Response With Immunotherapy in a Patient With Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gallbladder

2021 ◽  
Vol 11 ◽  
Author(s):  
Chao Liu ◽  
Xiangwei Hua ◽  
Zhen Yang ◽  
Yuan Guo ◽  
Liqun Wu ◽  
...  
Keyword(s):  
Emission Tomography ◽  
Neuroendocrine Neoplasms ◽  
Case Presentation ◽  
Positive Expression ◽  
Positron Emission ◽  
Positive Score ◽  
Gallbladder Adenocarcinoma ◽  
Upper Abdominal ◽  
New Diagnosis

BackgroundPrimary neuroendocrine tumors of the gallbladder (GB-NETs) are rare, accounting for 2% of all gallbladder cancers. Among GB-NETs, mixed neuroendocrine non-neuroendocrine neoplasms of the gallbladder (GB-MiNENs) are sporadic.Case PresentationA 56-year-old woman admitted to our hospital due to right upper abdominal pain of 3 days duration. She underwent positron emission tomography/computed tomography, which showed multiple metastatic tumors and was unsuitable for operation. Initially, the patient was diagnosed with gallbladder adenocarcinoma. She underwent PD-1 inhibitor or combined with chemotherapy considering the PD-L1 high positive score. In the latter, the patient has the opportunity of surgery, and the new diagnosis was MiNENs. She achieved long-term disease control and has been alive from the first diagnosis.ConclusionThis case might support the strategy that PD-1 inhibitor could provide a feasible treatment option for MiNENs of gallbladder patients with the positive expression of PD-L1 in the future.

Value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of pulmonary artery activity in patients with Takayasu’s arteritis

2020 ◽  
Author(s):  
Wei Gao ◽  
Juan-Ni Gong ◽  
Xiao-Juan Guo ◽  
Jiao-Yan Wu ◽  
Xiao-Ying Xi ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Inflammatory Markers ◽  
Pulmonary Angiography ◽  
Emission Tomography ◽  
Therapeutic Effects ◽  
Radiological Imaging ◽  
Positron Emission ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Aims To explore the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the detection of active pulmonary artery (PA) lesions in patients with Takayasu’s arteritis (TA). Methods and results Consecutive TA patients with PA involvement were prospectively recruited. Clinical activity was assessed according to the National Institutes of Health (NIH) criteria. CT pulmonary angiography (CTPA) or magnetic resonance pulmonary angiography was performed for evaluation of vascular structural characteristics, and mural thickening was considered as radiologically active. A vascular segment with 18F-FDG uptake ≥ liver was considered as PET-active. A total of 38 18F-FDG PET/CT scans were performed in 29 patients. In terms of disease activity, the sensitivity of 18F-FDG PET/CT did not significantly differ from radiological imaging (71.4% vs. 92.9%, P = 0.250), but 18F-FDG PET/CT had higher specificity (91.7% vs. 37.5%, P = 0.001) and accuracy (84.2% vs. 57.9%, P = 0.022). Although the majority of PET-active PA segments (54.9%) showed mural thickening, 14 PA segments with normal structure were also PET-active. 18F-FDG activity did not significantly differ between the PA and aorta in clinically active patients. In addition, 18F-FDG activity of the PA was positively correlated with inflammatory markers. Changes in 18F-FDG activity in PA during follow-up reflected therapeutic effects. Conclusion 18F-FDG PET/CT can effectively evaluate PA activity in TA patients, and its diagnostic performance is superior to radiological imaging. The 18F-FDG activity of PA shows a good correlation with clinical disease status and inflammatory markers and can be used to monitor therapeutic effects.

scholarly journals Detection of Inflammatory Aortopathies Using Multimodality Imaging

2019 ◽  
Vol 12 (7) ◽  
Author(s):  
John P. Bois ◽  
Vidhu Anand ◽  
Nandan S. Anavekar
Keyword(s):  
Multimodality Imaging ◽  
Clinical Problem ◽  
Emission Tomography ◽  
Tissue Sampling ◽  
Resonance Imaging ◽  
Tissue Samples ◽  
Positron Emission ◽  
Ultrasound Computed Tomography ◽  
Diagnostic Criterion

Diagnosis of the inflammatory aortopathies and importantly, their distinction in the later stages of disease from genetically mediated or acquired (degenerative) aortopathy remains a challenging clinical problem. Historically, the diagnosis of inflammatory aortopathy has required tissue sampling and pathological assessment. Although histological diagnosis remains an important diagnostic criterion, the ability to obtain sufficient tissue samples is problematic and requires invasive approaches that pose important risk. Continuing refinement in the capabilities of multimodality imaging, including ultrasound, computed tomography, magnetic resonance imaging, and positron emission tomography provides important insights into the broad spectrum of disease which comprise the inflammatory aortopathies. This review examines the current and emerging role of multimodality imaging in the evaluation of aortitis.

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