Three‐dimensional terrain corrections for mise‐à‐la‐masse and magnetometric resistivity surveys

Geophysics ◽  
1984 ◽  
Vol 49 (10) ◽  
pp. 1718-1729 ◽  
Author(s):  
G. L. Oppliger

Three‐dimensional modeling of topographic effects in mise‐à‐la‐masse and magnetometric resistivity surveys is accomplished using the surface integral equation method. The technique provides a means for (1) analyzing these effects on earth models of homogeneous conductivity; and (2) removing terrain effects from field data. A new method combining current source images with surface charge is developed to treat the electric field boundary conditions at the air‐earth interface. The method uses an image of each subsurface current source positioned above the surface, so as to induce a surface charge distribution which approximately cancels the charge distribution induced by the subsurface current source. The resulting residual surface charge distribution varies spatially more gradually than either of the original charge distributions, and hence may be represented accurately on a coarsely segmented model surface with simple basis functions. The topographic surface is modeled by a finite number of facets, each with constant slope and surface charge density. Charge values are obtained with an iterative solution technique. Surface electric fields are calculated from the surface charge distribution, current sources, and images. The magnetic field is found by evaluating a surface integral involving surface slopes and electric fields. The numerical solution is verified by comparisons with dipole‐dipole resistivity results from a two‐dimensional finite‐element model of a valley, and with analytic solutions for the magnetic fields over a dipping interface. Methods for terrain correcting mise‐à‐la‐masse and magnetometric resistivity data are demonstrated with examples using actual field measurements. The results of this study show that (1) rugged topography can significantly distort measurements in mise‐à‐la‐masse and magnetometric resistivity surveys; and (2) the described modeling technique provides an effective means of calculating terrain corrections for both the mise‐à‐la‐masse and magnetometric resistivity methods over complex three‐dimensional topography.

Cells ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1519
Author(s):  
Leixin Ouyang ◽  
Rubia Shaik ◽  
Ruiting Xu ◽  
Ge Zhang ◽  
Jiang Zhe

Many bio-functions of cells can be regulated by their surface charge characteristics. Mapping surface charge density in a single cell’s surface is vital to advance the understanding of cell behaviors. This article demonstrates a method of cell surface charge mapping via electrostatic cell–nanoparticle (NP) interactions. Fluorescent nanoparticles (NPs) were used as the marker to investigate single cells’ surface charge distribution. The nanoparticles with opposite charges were electrostatically bonded to the cell surface; a stack of fluorescence distribution on a cell’s surface at a series of vertical distances was imaged and analyzed. By establishing a relationship between fluorescent light intensity and number of nanoparticles, cells’ surface charge distribution was quantified from the fluorescence distribution. Two types of cells, human umbilical vein endothelial cells (HUVECs) and HeLa cells, were tested. From the measured surface charge density of a group of single cells, the average zeta potentials of the two types of cells were obtained, which are in good agreement with the standard electrophoretic light scattering measurement. This method can be used for rapid surface charge mapping of single particles or cells, and can advance cell-surface-charge characterization applications in many biomedical fields.


2010 ◽  
Vol 12 (12) ◽  
pp. 1718-1721 ◽  
Author(s):  
Sergey Sigalov ◽  
Mikhael D. Levi ◽  
Gregory Salitra ◽  
Doron Aurbach ◽  
Joachim Maier

Nanoscale ◽  
2021 ◽  
Author(s):  
Feng Chen ◽  
Jin He ◽  
Prakash Manandhar ◽  
Yizi Yang ◽  
Peidang Liu ◽  
...  

The distribution of surface charge and potential of cell membrane plays an indispensable role in cellular activities. However, probing surface charge of live cells in physiological conditions, until recently, remains...


1996 ◽  
Vol 74 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Edward K. Koepf ◽  
Leslie D. Burtnick

Gelsolin purified from horse plasma carries a surface charge distribution that greatly influences how the protein unfolds, aggregates, or precipitates as a function of temperature or concentration of chemical denaturant. Modification of gelsolin with fluorescein isothiocyanate replaces positive charges on amine groups with bulky, negatively charged fluorescein moieties. This postpones thermally induced precipitation by about 10 °C [Koepf, E.K., and Burtnick, L.D. 1993. Eur. J. Biochem. 212: 713–718]. Interaction with cations such as Ca2+ or guanidinium+ also alters the surface charge on gelsolin. This affects the structure of the protein in solution, modifies the pathway for unfolding, and moderates the onset of precipitation induced by chemical denaturants or heat. Denaturation of gelsolin is not interpretable in terms of a simple two-state cooperative mechanism. The pathway to a denatured state and intermediate structures present along the way depend upon the agent used to unfold the protein.Key words: gelsolin; denaturation, chemical, thermal, circular dichroism.


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