Management of first-episode psychosis

2001 ◽  
Vol 7 (2) ◽  
pp. 133-140 ◽  
Author(s):  
Elizabeth Spencer ◽  
Max Birchwood ◽  
Dermot McGovern
Keyword(s):  
Treatment Outcome ◽  
First Episode Psychosis ◽  
First Episode ◽  
Not Given ◽  
Long Duration ◽  
Episode Psychosis ◽  
Poor Treatment ◽  
Poor Treatment Outcome ◽  
Early Intervention In Psychosis

Over recent years early intervention in psychosis has fired the imagination of clinicians and researchers, following the publication of several studies linking a long duration of psychosis prior to receiving treatment with a poor treatment outcome: a relationship that has been cogently argued to be independent of illness factors (e.g. Scully et al, 1997). Most influential was Wyatt's (1991) review of 22 studies, in which relatively similar groups of patients suffering from schizophrenia were, or were not, given antipsychotic medication early in the course of their illness. This pointed towards an improved long-term course in schizophrenia with early treatment.

Long-Term Effect of Haloperidol, Olanzapine, and Risperidone on Plasma Prolactin Levels in Patients With First-Episode Psychosis

2012 ◽  
Vol 32 (6) ◽  
pp. 804-808 ◽  
Author(s):  
Rocio Pérez-Iglesias ◽  
Ignacio Mata ◽  
Obdulia Martínez-García ◽  
M. Teresa Garcia-Unzueta ◽  
Jose Antonio Amado ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
Term Effect ◽  
First Episode ◽  
Plasma Prolactin ◽  
Long Term Effect ◽  
Episode Psychosis

scholarly journals Effects of Long-Term Multimodal Psychosocial Treatment on Antipsychotic-Induced Metabolic Changes in Patients With First Episode Psychosis

2018 ◽  
Vol 9 ◽  
Author(s):  
Martina Rojnic Kuzman ◽  
Dina Bosnjak Kuharic ◽  
Ivana Kekin ◽  
Porin Makaric ◽  
Zoran Madzarac ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
Metabolic Changes ◽  
Psychosocial Treatment ◽  
First Episode ◽  
Episode Psychosis

Trajectories after first-episode psychosis: Complement to ambiguous outcomes of long-term antipsychotic treatment by exploring a few hidden cases

2018 ◽  
Vol 13 (4) ◽  
pp. 895-901 ◽  
Author(s):  
Chen-Chung Liu ◽  
Yi-Ting Lin ◽  
Chih-Min Liu ◽  
Ming H. Hsieh ◽  
Yi-Ling Chien ◽  
...  
Keyword(s):  
First Episode Psychosis ◽  
First Episode ◽  
Antipsychotic Treatment ◽  
Episode Psychosis

scholarly journals First-episode psychosis: primary care experience and implications for service development

2009 ◽  
Vol 33 (5) ◽  
pp. 165-168 ◽  
Author(s):  
Mamdouh El-Adl ◽  
John Burke ◽  
Karen Little
Keyword(s):  
Primary Care ◽  
Early Intervention ◽  
General Practitioners ◽  
Psychiatric Service ◽  
First Episode Psychosis ◽  
Health Clinic ◽  
First Episode ◽  
Care Experience ◽  
Episode Psychosis ◽  
Early Intervention In Psychosis

Aim and MethodsTo capture the local primary care experience of first-episode psychosis before developing a local early intervention in psychosis service. A survey of Northamptonshire general practitioners (GPs) using a confidential questionnaire was carried out.ResultsOut of 284 GPs, 123 (43%) responded. General practitioners are unlikely to start treatment before referring to a specialist service: 63 GPs (51% of responders) start treatment in 10% or less of individuals with first-episode psychosis and 19 (15.5%) GPs start treatment in 75% or more before referring them to psychiatric service; 42 GPs (34%) refer those who request/accept a referral and 66 GPs (53%) refer all even if they refuse. Overall, 92 GPs (74%) agreed that an early intervention in psychosis service is needed and 77 (63%) GPs welcome having a mental health clinic in their surgery.Clinical ImplicationsIndividuals are more likely to accept referral to a psychiatric service if offered than to ask for it. People disengaging, stigma, the service being difficult to access/inappropriate and carers' lack of knowledge about mental illness are the likely causes for delayed referral.

scholarly journals Cannabis use and first-episode psychosis: relationship with manic and psychotic symptoms, and with age at presentation

2013 ◽  
Vol 44 (3) ◽  
pp. 499-506 ◽  
Author(s):  
J. M. Stone ◽  
H. L. Fisher ◽  
B. Major ◽  
B. Chisholm ◽  
J. Woolley ◽  
...  
Keyword(s):  
Longitudinal Design ◽  
First Episode Psychosis ◽  
Cannabis Use ◽  
Daily Functioning ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Time Points ◽  
Manic Symptoms ◽  
Episode Psychosis ◽  
Early Intervention In Psychosis

BackgroundCannabis use has been reported to be associated with an earlier onset of symptoms in patients with first-episode psychosis, and a worse outcome in those who continue to take cannabis. In general, studies have concentrated on symptoms of psychosis rather than mania. In this study, using a longitudinal design in a large naturalistic cohort of patients with first-episode psychosis, we investigated the relationship between cannabis use, age of presentation to services, daily functioning, and positive, negative and manic symptoms.MethodClinical data on 502 patients with first-episode psychosis were collected using the MiData audit database from seven London-based Early Intervention in psychosis teams. Individuals were assessed at two time points – at entry to the service and after 1 year. On each occasion, the Positive and Negative Syndrome Scale, Young Mania Rating Scale and Global Assessment of Functioning Scale disability subscale were rated. At both time points, the use of cannabis and other drugs of abuse in the 6 months preceding each assessment was recorded.ResultsLevel of cannabis use was associated with a younger age at presentation, and manic symptoms and conceptual disorganization, but not with delusions, hallucinations, negative symptoms or daily functioning. Cannabis users who reduced or stopped their use following contact with services had the greatest improvement in symptoms at 1 year compared with continued users and non-users. Continued users remained more symptomatic than non-users at follow-up.ConclusionsEffective interventions for reducing cannabis use may yield significant health benefits for patients with first-episode psychosis.

First-episode psychosis intervention – description of our early intervention model

2017 ◽  
Vol 41 (S1) ◽  
pp. s823-s823
Author(s):  
B. Melo ◽  
C. Alves Pereira ◽  
R. Cajão ◽  
J. Ribeiro Silva ◽  
S. Pereira ◽  
...  
Keyword(s):  
Early Intervention ◽  
Relapse Rate ◽  
First Episode Psychosis ◽  
First Episode ◽  
Child Psychiatrist ◽  
Duration Of Untreated Psychosis ◽  
Intervention Model ◽  
Episode Psychosis ◽  
Clinical Records ◽  
Early Intervention In Psychosis

IntroductionThe research about the benefits of early diagnosis and treatment of first-episode psychosis had significantly increased in last decades. There have been several early intervention programs in psychotic disease, implemented worldwide, in order to improve the prognosis of these psychotic patients.ObjectivesTo present a brief description of the first-episode psychosis intervention team of Tondela-Viseu Hospital Centre–Portugal and its model. We aim to further characterize our population and describe its evolution since 2008.AimsWe aim to clarify the benefits of an early intervention in psychosis.MethodsWe conducted a retrospective cohort study of patients being followed by our team from November 2008 to September 2016. Demographic and medical data were collected (such as diagnosis, duration of untreated psychosis, treatments and its clinical effectiveness, relapse rate and hospital admissions) in patient's clinical records. The intervention model protocol of this team was also described and analyzed.ResultsThis multidisciplinary team consists of three psychiatrists, one child Psychiatrist, one psychologist and five reference therapists (areas of nursing, social service and occupational therapy). It includes patients diagnosed with first-episode psychosis, aged 16 to 42 years old, followed for five years. The team followed, since its foundation, 123 patients, mostly male. The most prevalent diagnosis are schizophrenia and schizophreniform psychosis. The team is currently following 51 patients.ConclusionsThis team's intervention have progressively assumed a more relevant importance in the prognosis of patients with first-episode psychosis, by reducing the duration of untreated psychosis, the relapse rate and by promoting social reintegration.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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