Treatment of Mood Disorder Associated with Binswanger's Disease

1989 ◽  
Vol 154 (2) ◽  
pp. 259-261 ◽  
Author(s):  
Eileen M. Joyce ◽  
Raymond Levy
Keyword(s):  
Quality Of Life ◽  
White Matter ◽  
Mood Disorder ◽  
Cerebrovascular Disorder ◽  
Deep White Matter ◽  
Affective Component ◽  
Binswanger’S Disease ◽  
Affective Disturbance ◽  
Binswanger's Disease

Binswanger's disease is a cerebrovascular disorder affecting deep white matter and is associated with dementia and affective disturbance. In the case reported, the mood disorder was successfully treated with a combination of lithium and amitriptyline, resulting in an improved quality of life despite continuing cognitive decline. This underlines the importance of treating the affective component of organic dementing conditions on its own merit.

Dementia, deep white matter damage and hypertension: ‘Binswanger's disease’

1981 ◽  
Vol 11 (1) ◽  
pp. 39-48 ◽  
Author(s):  
I. Janota
Keyword(s):  
White Matter ◽  
Intellectual Impairment ◽  
White Matter Damage ◽  
White Matter Changes ◽  
Deep White Matter ◽  
The Past ◽  
Binswanger’S Disease ◽  
Binswanger's Disease ◽  
Organic Intellectual ◽  
Organic Dementia

SYNOPSISThe clinical and neuropathological features are reported of 7 patients with organic intellectual impairment or dementia, hypertension and ischaemic destruction predominantly of the deep white matter of the cerebral hemispheres resembling that seen in infarction. The white matter changes have been dismissed as rare in the past, usually under the name of Binswanger's disease or subcortical arteriosclerotic encephalopathy, and without much concern for hypertension. There are now indications that this sort of case may not be uncommon. It can be suspected in life on CT scans. The accuracy of assessment of the pathological substrate of organic dementia, and therefore the strategies of research and treatment, might well benefit from further clinicopathological studies.

Binswanger's Disease: Some Neuropsychological Considerations

1990 ◽  
Vol 3 (1) ◽  
pp. 31-40 ◽  
Author(s):  
David J. Libon ◽  
Mary Scanlon ◽  
Rodney Swenson ◽  
H. Branch Coslet
Keyword(s):  
White Matter ◽  
Neuropsychological Functioning ◽  
Periventricular White Matter ◽  
Delayed Recall ◽  
Neuropsychological Measures ◽  
Deep White Matter ◽  
Binswanger’S Disease ◽  
Binswanger's Disease ◽  
Dementing Illness ◽  
Almost All

The literature regarding Binswanger's disease is reviewed. Emphasis is placed on reviewing the neuropsychological literature related to Binswanger's disease. In addition, a retrospective analysis was carried out among four groups of subjects (N = 61) who were divided according to the presence or absence of dementia and deep white-matter alterations. A main effect for deep white-matter alterations was found for almost all measures of diastolic and systolic blood pressure. Among the two nondemented groups there was an effect of deep white matter alteration on neuropsychological functioning. Subjects with deep white matter changes performed worse on tests of immediate and delayed recall of a prose passage. Among the two demented groups there were no differences on any of the neuropsychological measures, although subjects with deep white matter alterations exhibited a higher incidence of focal neurologic signs and stroke. We conclude that Binswanger's disease is probably more prevalent than currently appreciated. Also, among clinically nondemented individuals periventricular white-matter alterations may be associated with subtle but definable neuropsychological deficits, and these individuals may be at risk for developing a dementing illness. (J Geriatr Psychiatry Neurol 1990;3:31-40).

Predictors of quality of life in type 2 diabetes patients with schizophrenia, major mood disorder, and without mental illness

2011 ◽  
Vol 20 (9) ◽  
pp. 1419-1425 ◽  
Author(s):  
Faith Dickerson ◽  
Karen Wohlheiter ◽  
Deborah Medoff ◽  
Lijuan Fang ◽  
Julie Kreyenbuhl ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Mental Illness ◽  
Mood Disorder ◽  
Diabetes Patients

Ischemic white matter disease (Binswanger's disease)

2016 ◽  
pp. 13-14
Author(s):  
Saltanat Kamenova ◽  
Aida Kondybayeva ◽  
Assiya Akanova
Keyword(s):  
White Matter ◽  
White Matter Disease ◽  
Binswanger’S Disease ◽  
Binswanger's Disease

scholarly journals Trichotillomania in a dementia case

2011 ◽  
Vol 5 (1) ◽  
pp. 58-60
Author(s):  
Leonardo Caixeta ◽  
Danielly Bandeira Lopes
Keyword(s):  
White Matter ◽  
Vascular Dementia ◽  
Hair Pulling ◽  
Dementia Case ◽  
Binswanger’S Disease ◽  
Binswanger's Disease ◽  
The Right

Abstract We report an 87-year-old male case of hair pulling associated with a white-matter vascular dementia (Binswanger's disease). Trichotillomania in our case did not resolve using mirtazapine or anticholinesterasic medication. Trichotillomania seems to be related to a form of perseveration associated with dementia. The findings in this case suggest the abnormality involving white matter in the pathogenesis of trichotillomania, may constitute a defect in connectivity in the right frontal-subcortical circuit.

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