The Nithsdale Schizophrenia Surveys X: Obstetric Complications, Family History and Abnormal Movements

1992 ◽  
Vol 160 (6) ◽  
pp. 799-805 ◽  
Author(s):  
Robin G. McCreadie ◽  
David J. Hall ◽  
Ian J. Berry ◽  
Lesley J. Robertson ◽  
James I. Ewing ◽  
...  
Keyword(s):  
Family History ◽  
Tardive Dyskinesia ◽  
Psychiatric Illness ◽  
Obstetric Complications ◽  
Degree Relative ◽  
Drug Induced ◽  
Abnormal Movements ◽  
Significant Difference ◽  
Schizophrenic Patients ◽  
History Of

Obstetric histories of 54 schizophrenic patients and 114 siblings were obtained from their mothers and scored using the Obstetric Complications Scale. There was no statistically significant difference in the proportion of schizophrenic patients (35%) and siblings (29%) who had at least one definite obstetric complication. There was no evidence that schizophrenic patients with a history of obstetric complications were less likely to have a first-degree relative with a history of psychiatric illness leading to in-patient care. Schizophrenic patients with a history of obstetric complications were more likely to have drug-induced Parkinsonism. There was a trend for tardive dyskinesia to be more common in those schizophrenic patients with no obstetric complications but a family history of schizophrenia.

scholarly journals Prolonged Methamphetamine-Induced Psychosis: Difference With Schizophrenia

2019 ◽  
Author(s):  
Hamid Reza Ahmadkhaniha ◽  
Kaveh Alavi ◽  
Fatemeh Hadi
Keyword(s):  
Family History ◽  
Obstetric Complications ◽  
Medical Sciences ◽  
Neurological Soft Signs ◽  
Demographic Questionnaire ◽  
Significant Difference ◽  
Other Substances ◽  
Schizophrenic Patients ◽  
History Of ◽  
Close Relatives

The main objective of the present study was to compare the distribution of underlying factors such as neurological soft signs, obstetric complications, and family history of psychiatric disorders between two groups of schizophrenic patients and patients with prolonged methamphetamine-induced psychosis. In a case-control study, 30 patients with prolonged methamphetamine-induced psychosis and 30 patients with schizophrenia were selected. Data were collected through a demographic questionnaire, the Buchanan and Heinrichs’ Neurological Evaluation Scale (NES), the Lewis-Murray’s Obstetric Complications Scale (LMOCS), and the Weissman’s Family History Screen (FHS). Mean scores of the neurological soft signs (±SD) in the two groups of schizophrenic patients and patients with prolonged methamphetamine-induced psychosis were 15.7±8.7 and 11.7±6.2, respectively (P=0.040), and a significant difference was observed in the sensory integration between the two groups (P=0.022). Obstetric complications revealed similar distributions in the two groups. Patients with prolonged methamphetamine-induced psychosis reported higher prevalence of alcohol and other substances use disorders (P=0.003 and P=0.001, respectively) in their close relatives; however, the distributions of other disorders were not statistically different between the two groups’ close relatives. Similarities and differences in certain aspects were observed between the two groups, suggesting susceptibility for psychosis in patients with prolonged methamphetamine-induced psychosis; yet we found diversities that distinguish the two disorders. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(4):235-243

The Expression of Schizophrenia, Affective Disorder and Vulnerability to Tardive Dyskinesia in an Extensive Pedigree

1988 ◽  
Vol 153 (3) ◽  
pp. 376-381 ◽  
Author(s):  
John L. Waddington ◽  
Hanafy A. Youssef
Keyword(s):  
Family History ◽  
Tardive Dyskinesia ◽  
Movement Disorder ◽  
Affective Disorder ◽  
Psychiatric Illness ◽  
Late Onset ◽  
Psychiatric Morbidity ◽  
Neuroleptic Treatment ◽  
History Of

The demography, psychiatric morbidity, and motor consequences of long-term neuroleptic treatment in the 14 children born to a father with a family history of chronic psychiatric illness and a mother with a late-onset affective disorder resulting in suicide are documented. Twelve siblings lived to adulthood, nine of whom were admitted to a psychiatric hospital in their second or third decade, and required continuous in-patient care; five remaining in hospital, with long-term exposure to neuroleptics, had chroniC., deteriorating, schizophrenic illness and emergence of movement disorder. Two siblings showed no evidence of psychosis but developed a late-onset affective disorder. The implications for the issues of homotypia, vulnerability to involuntary movements, and interaction with affective disorder are discussed.

scholarly journals Psychiatry as a career: A survey of factors affecting students’ interest in Psychiatry as a career

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Mubashir Aslam ◽  
Tahir Taj ◽  
Arif Ali ◽  
Nasira Badar ◽  
Farzan Saeed ◽  
...  
Keyword(s):  
Medical Students ◽  
Family History ◽  
Medical School ◽  
Psychiatric Illness ◽  
P Value ◽  
Factors Affecting ◽  
Medical Graduates ◽  
Significant Difference ◽  
History Of ◽  
Self Administered Questionnaire

The objectives of this study were to determine the characteristics of medical students and graduates interested in choosing psychiatry as a career and the obstacles in choosing this field of medicine. Two private and two public medical institutes were surveyed from June 2007 to August 2007. A self-administered questionnaire was distributed to third, fourth and final year students and to medical graduates doing their internship in these four medical institutes.A total of 909 medical students and graduates participated in the study. Seventeen percent of participants responded positively regarding their interest in psychiatry as a career. Significantly higher proportion belonged to private medical institutes (14% vs. 24%, P-value =0.001). There was no significant difference in reporting interest for psychiatry in regard to age, sex, year in medical school and whether or not the participant had done a psychiatry ward rotation. However significantly higher proportion of participants (22%, n=43) were reporting their interest in the field of psychiatry who had done more than a month long psychiatry ward rotation as compared to those participants (14%, n=54) with less than a month or no psychiatry rotation (P-value=0.01). More students were reporting their interest in psychiatry with a family history of psychiatric illness as compared to without family history (24% vs 16%, P-value=0.03). In conclusion, students and graduates with more than a month long rotation in psychiatry, studying in private medical colleges and with a family history of psychiatric illness were more interested in choosing psychiatry as a career.

Schizophrenics with a family history of bipolar disorder. Possible involvement of obstetric complications

1993 ◽  
Vol 8 (4) ◽  
pp. 223-226
Author(s):  
H Verdoux ◽  
M Bourgeois
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Case Reports ◽  
Obstetric Complications ◽  
Schizophrenic Patients ◽  
History Of ◽  
The Continuum

SummaryThe case reports of two DSM III-R schizophrenic patients with a family history of bipolar disorder are presented. The two patients had a history of severe obstetric complications (OCs). These cases are discussed in the light of neurodevelopmental theories of schizophrenia and in the continuum view of psychosis.

Prevalence of Familiality, Obstetric Complications, and Structural Brain Damage in Schizophrenic Patients

1988 ◽  
Vol 153 (2) ◽  
pp. 191-197 ◽  
Author(s):  
V. L. Nimgaonkar ◽  
S. Wessely ◽  
R. M. Murray
Keyword(s):  
Family History ◽  
Brain Damage ◽  
Obstetric Complications ◽  
Ventricular Enlargement ◽  
Clinical Variables ◽  
Structural Brain Damage ◽  
Schizophrenic Patients ◽  
History Of ◽  
Structural Brain

Schizophrenic in-patients with and without a family history were identified prospectively. The two groups did not differ with respect to clinical variables, ventricular enlargement, prevalence of cortical sulcal widening, or a history of obstetric complications, even when a variety of definitions of familiality were used.

scholarly journals Influence of Family Environment on Childhood Emotional and Behavioural Disorders

2020 ◽  
Vol 7 (44) ◽  
pp. 2544-2549
Author(s):  
Ganga G. Kaimal ◽  
Varghese P. Punnoose ◽  
Saibunnisa Beevi K
Keyword(s):  
Family History ◽  
Psychiatric Disorders ◽  
Emotional Disorders ◽  
Family Environment ◽  
Psychiatric Illness ◽  
Family Type ◽  
Behavioural Disorders ◽  
Child Psychiatric ◽  
Significant Difference ◽  
History Of

BACKGROUND India has a large proportion of child and adolescent population. Psychiatric disorders are common among children and adolescents, but they are often underdiagnosed. Family environment influences psychopathology in young children. Identification of risk factors for child psychiatric disorders can lead to early identification of children at risk and facilitation of preventive interventions. METHODS The study was conducted among 103 children attending the Child Guidance Clinic (CGC) in a tertiary care institute in Kerala. A specially prepared proforma was used to obtain the sociodemographic profile and clinical variables. Global Family Environment Scale was used to assess the quality of family environment. ICD 10 classification of mental and behavioural disorders was used for making diagnosis, and Ravens Coloured Progressive Matrices was used for assessing intelligence. RESULTS Emotional disorders were seen more commonly in girls, and in older age group. Children with behavioural disorders were below average in academics and the difference between the groups was statistically significant. No statistically significant difference was found between the groups in socioeconomic status, locality, family type, family history of psychiatric illness, and in family environment. CONCLUSIONS Though there was no statistically significant difference, family history of psychiatric illness and poor and moderately unsatisfactory family environment was observed in a large proportion of children. This finding may have implication in management of childhood psychiatric disorders. KEYWORDS Family Environment, Children, Emotional Disorders, Behavioural Disorders

Obstetric complications in patients with schizophrenia and their unaffected siblings

2005 ◽  
Vol 20 (1) ◽  
pp. 28-34 ◽  
Author(s):  
M. Walshe ◽  
C. McDonald ◽  
M. Taylor ◽  
J. Zhao ◽  
P. Sham ◽  
...  
Keyword(s):  
Risk Factor ◽  
Family History ◽  
Genetic Susceptibility ◽  
Environmental Risk ◽  
Obstetric Complications ◽  
Control Group ◽  
Environmental Risk Factor ◽  
Schizophrenic Patients ◽  
History Of ◽  
Elevated Rate

AbstractObjectiveWe sought to explore whether obstetric complications (OCs) are more likely to occur in the presence of familial/genetic susceptibility for schizophrenia or whether they themselves represent an independent environmental risk factor for schizophrenia.MethodsThe presence of OCs was assessed through maternal interview on 216 subjects, comprising 36 patients with schizophrenia from multiply affected families, 38 of their unaffected siblings, 31 schizophrenic patients with no family history of psychosis, 51 of their unaffected siblings and 60 normal comparison subjects. We examined the familiality of OCs and whether OCs were commoner in the patient and sibling groups than in the control group.ResultsOCs tended to cluster within families, especially in multiply affected families. Patients with schizophrenia, especially those from multiply affected families, had a significantly higher rate of OCs compared to normal comparison subjects, but there was no evidence for an elevated rate of OCs in unaffected siblings.ConclusionOur data provides little evidence for a link between OCs and genetic susceptibility to schizophrenia. If high rates of OCs are related to schizophrenia genes, this relationship is weak and will only be detected by very large sample sizes.

scholarly journals The Nithsdale Schizophrenia Surveys

1994 ◽  
Vol 165 (3) ◽  
pp. 340-346 ◽  
Author(s):  
R. G. Mccreadie ◽  
M. A. Connolly ◽  
D. J. Williamson ◽  
R. W. B. Athawes ◽  
D. Tilak-Singh
Keyword(s):  
Family History ◽  
Personality Traits ◽  
Social Adjustment ◽  
Obstetric Complications ◽  
Childhood And Adolescence ◽  
Schizotypal Personality ◽  
Clinical Correlates ◽  
Syndrome Scale ◽  
Schizophrenic Patients ◽  
History Of

BackgroundThe aim was to examine in a population of schizophrenic patients the clinical correlates of ‘neurodevelopmental’ schizophrenia and their relationship to putative aetiological factors.MethodPremorbid social adjustment, premorbid schizoid and schizotypal personality traits, and the obstetric history of 40 schizophrenic patients and their 102 sibs were assessed through interviews with their mothers. Patients' premorbid level of intelligence was assessed by the National Adult Reading Test and current symptoms by the Positive and Negative Syndrome Scale and the Subjective Deficit Syndrome Scale.ResultsPatients had more schizoid and schizotypal traits than their sibs. They showed a deterioration in social adjustment between childhood and adolescence; sibs' social adjustment improved. There were statistically significant associations between current negative schizophrenic symptoms, premorbid deterioration in social adjustment, and schizoid and schizotypal personality traits, and between an early age of onset of illness and the same premorbid assessments. There was no evidence that patients with a family history of severe mental illness leading to hospitalisation, or a history of definite obstetric complications, had poorer premorbid functioning or more severe current symptoms.ConclusionsWe have confirmed clinical correlates of ‘neurodevelopmental’ schizophrenia but found no association between these and obstetric complications or a family history of severe mental disorder.

History of obstetric complications, family history, and CT scan findings in schizophrenic patients

1990 ◽  
Vol 3 (5-6) ◽  
pp. 311-314 ◽  
Author(s):  
Ravinder Reddy ◽  
Sukdeb Mukherjee ◽  
David B. Schnur ◽  
James Chin ◽  
Gustav Degreef
Keyword(s):  
Family History ◽  
Ct Scan ◽  
Obstetric Complications ◽  
Schizophrenic Patients ◽  
History Of

Psychiatric disorder in young adults born very preterm: Role of family history

2008 ◽  
Vol 23 (7) ◽  
pp. 527-531 ◽  
Author(s):  
M. Walshe ◽  
L. Rifkin ◽  
M. Rooney ◽  
E. Healy ◽  
C. Nosarti ◽  
...  
Keyword(s):  
Young Adults ◽  
Family History ◽  
Psychiatric Disorder ◽  
Psychiatric Illness ◽  
Degree Relative ◽  
Interview Schedule ◽  
Very Preterm ◽  
Increased Risk ◽  
History Of

AbstractObjectiveTo investigate whether young adults born very preterm (VPT) (<33 weeks) are at increased risk for psychiatric illness in adulthood and whether a family history of psychiatric disorder further increases this risk.MethodsWe assessed 169 VPT and 101 term born individuals using the Clinical Interview Schedule – Revised.ResultsYoung adults born VPT had an increased risk for psychiatric disorder compared to controls (OR = 3.1, 95% CI = 1.1–8.6, p = 0.03). Those born VPT who had a history of psychiatric disorder in a first-degree relative, had an increase in risk for psychiatric disorder compared to those born VPT without a family history (OR = 5.2, 95% CI = 1.8–14.9, p = 0.002).ConclusionIndividuals born VPT are at increased risk of psychiatric illness in young adulthood compared to controls. In addition, a family history of psychiatric disorder in a first-degree relative may leave young adults born VPT particularly vulnerable to psychiatric illness.

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