Controlled trial of exposure and response prevention in obsessive–compulsive disorder

1997 ◽  
Vol 171 (2) ◽  
pp. 135-139 ◽  
Author(s):  
Merran Lindsay ◽  
Rocco Crino ◽  
Gavin Andrews

BackgroundExposure and response prevention is considered a treatment of choice for obsessive–compulsive disorder (OCD). Yet there have been very few randomised controlled trials employing credible placebo conditions. This study compares exposure and response prevention with a general anxiety management intervention.MethodEighteen patients meeting DSM–IV criteria for OCD were randomly assigned to either exposure and response prevention or anxiety management. Both treatments involved approximately 15 hours of therapy over a three-week period.ResultsThere was a significant reduction in obsessive–compulsive symptoms following treatment with exposure and response prevention, while no change occurred in the control group. This was found to be statistically significant using a composite measure of OCD symptom severity, patient ratings of interference and therapist ratings of symptom severity.ConclusionsThese findings suggest that the symptom reductions associated with behaviour therapy for OCD are a result of the specific techniques of exposure and response prevention, rather than non-specific aspects of the therapy process. General anxiety management techniques are not effective in the treatment of OCD.

Author(s):  
Farzad Farhoodi ◽  
Javad Salehi Fadardi ◽  
Ali Ghanaie Chamanabad ◽  
Seyed Hamid Mirhoseini

Introduction: The aim of the present study was to compare the effectiveness of cognitive behavior therapy based on exposure and response prevention on the patients with contamination obsessive-compulsive disorder (OCD) and scrupulosity. Methods: The method was semi-experimental pretest-posttest design by control group. Sixty OCD participants who were suffering from scrupulosity and contamination OCD were diagnosed by means of diagnostic interviewing, Yale-Brown Obsessive-Compulsive Scale and Penn inventory of scrupulosity. They were selected through convenience sampling method and were assigned in two experimental groups and one control group (each group 20). The cognitive behavioral therapy based on exposure and response prevention was performed on the subjects in nine individual sessions for 45 minutes for each experimental group. The data were analyzed using SPSS Inc., Chicago, IL; Version 16 by the multivariate analysis of covariance. Results: The results of multivariate analysis of covariance and Bonferroni post hoc tests showed that cognitive behavioral therapy based on exposure and response prevention were effective in decreasing OCD in the experimental groups compared to the control group (0.001≥ P). Bonferroni post hoc test showed that there was a significant difference between the scrupulosity group and the contamination group and control group on the obsession variable (0.05 < P). There was no significant difference between the contamination group and the scrupulosity group on the compulsion variable (0.15 < p). Conclusion: The findings suggest that cognitive behavioral therapy based on exposure and response prevention could help alleviate symptoms of obsessive-compulsive disorder in both religious and contamination OCD.


2020 ◽  
Vol 20 (2) ◽  
pp. 101-120
Author(s):  
Ayça Aktaç Gürbüz ◽  
Orçun YORULMAZ ◽  
Gülşah DURNA

Scientific research into the reduction of stigmatization, particularly related to specific problems such as Obsessive-Compulsive Disorder (OCD), is scarce. In the present study, we examine the impact of a video-based antistigma intervention program for OCD in a pretest-posttest control group research. After being randomly assigned to either an intervention (n= 101) or control group (n= 96), the participants reported their attitudes on a hypothetical case vignette before and after OCD vs. Multiple Sclerosis (MS) videos, and again six months later as a follow up assessment. The mixed design analyses for the group comparisons indicated that although there was no significant difference in the measures of the control group, the participants watching the anti-stigma OCD video, in which the focus was psychoeducation and interaction strategies, reported significantly lower scores on social distances and negative beliefs for the case vignettes they read, and this difference was maintained six months later. Then, the present results indicate the effectiveness of our anti-stigma intervention program for OCD. Interventions to reduce stigmatization can also be viewed as effective tools for changing the attitudes of people toward OCD, although further research and applications are needed related to specific disorders if a longlasting impact is to be achieved.


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