scholarly journals Smoking cessation in severe mental illness: combined long-term quit rates from the UK SCIMITAR trials programme

2019 ◽  
pp. 1-3 ◽  
Author(s):  
Simon Gilbody ◽  
Emily Peckham ◽  
Della Bailey ◽  
Catherine Arundel ◽  
Paul Heron ◽  
...  

Summary Smoking contributes to health inequalities for people with severe mental illness (SMI). Although smoking cessation interventions are effective in the short term, there are few long-term trial-based estimates of abstinence. The SCIMITAR trials programme includes the largest trial to date of a smoking cessation intervention for people with SMI, but this was underpowered to detect anticipated long-term quit rates. By pooling pilot and full-trial data we found that quit rates were maintained at 12 months (OR = 1.67, 95% CI 1.02–2.73, P = 0.04). Policymakers can now be confident that bespoke smoking cessation interventions produce successful short- and long-term quitting.

2016 ◽  
Vol 238 ◽  
pp. R13-R21 ◽  
Author(s):  
Jonathan Portes

This paper examines the short and long-term impacts of the UK referendum on migration flows and migration policy. Even in the short term – before any policy change – the vote will affect migration flows directly and indirectly through both economic and other channels. Post Brexit, two key issues will need to be addressed. Will the UK preserve a substantial measure of preference for EU citizens in any new system? And will policy tilt in a liberal or restrictive direction?


1991 ◽  
Vol 18 (6) ◽  
pp. 729 ◽  
Author(s):  
PJS Fleming ◽  
RW Parker

Short- and long-term trials were conducted to determine the rate of decline of 1080 (sodium fluoroacetate) in meat baits used for poisoning wild dogs. Baits were injected with 0.2 ml of standard 1080 solution (nominal dose of 6.00 mg of pure 1080 per bait) and placed in the field. In the long-term trial, 10 baits were collected at 7 intervals between 3 h and 226 days, and analysed for residual 1080 by liquid chromatography. The recoverable 1080 content declined greatly over the first 48 days, although at 226 days all 10 baits retained some 1080. By 42.4 days the mean residual level of 1080 in the baits was predicted to be less than the theoretical LD99 for wild dogs. At the time of distribution, baits contained less than the LD50 for an average-sized eastern quoll. The LD99 for domestic cattle-dogs was predicted to be still present in baits at 72.9 days. Loss of 1080 from these baits was not correlated with rainfall, temperature or humidity. In the short-term trial, 10 baits were collected at 11 intervals up to 200 h. The recoverable 1080 content decreased by 3.09 mg (61% of the injected dose) within the first hour after injection and declined to a low of 2.70 mg at hour 50. The level of recovered 1080 then rose to 73% of the injected dose at hour 150.


2016 ◽  
Vol 1 (1) ◽  
pp. 68
Author(s):  
Lan-ying Zhu ◽  
Man C.M. Tsui ◽  
Da Li

<p>Globally, severe mental illness (SMI) causes both short-term and long-term disabilities (Royal College of Psychiatrists, 2009). In China, there are about 16 million people with SMI (Phillips et al., 2009).<strong> </strong>Secondary handicaps due to social stigma are common which result in severe deprivation of community re-integration (Social Exclusion Unit, 2004). Such alarming situations further highlight the pressing needs of developing culturally sensitive counseling strategies and practices.</p>


Children ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 276
Author(s):  
Judith Rittenschober-Böhm ◽  
Tanja Habermüller ◽  
Thomas Waldhoer ◽  
Renate Fuiko ◽  
Stefan M. Schulz ◽  
...  

Vaginal colonization with Ureaplasma (U.) spp. has been shown to be associated with adverse pregnancy outcome; however, data on neonatal outcome are scarce. The aim of the study was to investigate whether maternal vaginal colonization with U. spp. in early pregnancy represents a risk factor for adverse short- or long-term outcome of preterm infants. Previously, 4330 pregnant women were enrolled in an observational multicenter study, analyzing the association between vaginal U. spp. colonization and spontaneous preterm birth. U. spp. colonization was diagnosed via PCR analysis from vaginal swabs. For this study, data on short-term outcome were collected from medical records and long-term outcome was examined via Bayley Scales of Infant Development at 24 months adjusted age. Two-hundred-and-thirty-eight children were born <33 weeks gestational age. After exclusion due to asphyxia, malformations, and lost-to-follow-up, data on short-term and long-term outcome were available from 222 and 92 infants, respectively. Results show a significant association between vaginal U. spp. colonization and severe intraventricular hemorrhage (10.4% vs. 2.6%, p = 0.03), retinopathy of prematurity (21.7% vs. 10.3%, p = 0.03), and adverse psychomotor outcome (24.3% vs. 1.8%, OR 13.154, 95%CI 1.6,110.2, p = 0.005). The data suggest an association between vaginal U. spp. colonization in early pregnancy and adverse short- and long-term outcome of very preterm infants.


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