Blood-Pressure in Cardiazol Epilepsy

1939 ◽  
Vol 85 (357) ◽  
pp. 787-795 ◽  
Author(s):  
E. Guttmann ◽  
F. Reitmann

No problem in neurology has been approached from so many different angles as has the pathogenesis of the epileptic fit; yet it is far from being solved. Histological examination of the brains of epileptics, electric stimulalation of the human brain during operation, chemical analysis of the body fluids both in general and of the arterial and venous blood of the cerebral vessels in particular, measurements of the intracranial blood-flow, investigations into metabolic changes before, during, and after fits, electro-encephalographic studies, have produced an enormous wealth of data, which it has not, however, been possible to weld into a single theory. The most recent monograph on epilepsy—Kinnier Wilson's article on the subject in Bumke's Handbuch der Neurologie—speaks only of various “determinants” of the fit: the vascular, the humoral, etc.

Author(s):  
Chris Cooper

The heart is the organ that pumps blood around the body. If the heart stops functioning, blood does not flow. The driving force for this flow is the pressure difference between the arterial blood leaving the heart and the returning venous blood. ‘Blood pressure and blood flow’ first considers how blood pressure is measured and how blood pressure can affect health. High blood pressure is called hypertension and low blood pressure hypotension. Chronic hypertension has serious long-term adverse health consequences, but can be treated with improved lifestyle choices and a range of medicines, including anti-hypertensive drugs, beta blockers, and ACE inhibitor drugs. The different molecules affecting blood flow are also considered.


1970 ◽  
Vol 38 (1) ◽  
pp. 85-91 ◽  
Author(s):  
I. Sudhakaran Menon ◽  
J. Muscat-Baron ◽  
D. Weightman ◽  
H. A. Dewar

1. A considerable increase in the plasminogen activator content in the internal jugular venous blood as compared with that in the arterial blood was found in fifty patients. 2. Inhalation of 5% carbon dioxide in air was associated with increased plasminogen activator content in blood from the internal jugular vein in all the eight patients treated in this way. 3. It is suggested that the human brain makes a contribution of plasminogen activator to the circulation of the body and that the amount contributed is determined by the rate of the blood flow.


2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.


1967 ◽  
Vol 46 (2) ◽  
pp. 307-315 ◽  
Author(s):  
E. DON STEVENS ◽  
D. J. RANDALL

1. Changes in blood pressure in the dorsal aorta, ventral aorta and subintestinal vein, as well as changes in heart rate and breathing rate during moderate swimming activity in the rainbow trout are reported. 2. Blood pressures both afferent and efferent to the gills increased during swimming and then returned to normal levels within 30 min. after exercise. 3. Venous blood pressure was characterized by periodic increases during swimming. The pressure changes were not in phase with the body movements. 4. Although total venous return to the heart increased during swimming, a decreased blood flow was recorded in the subintestinal vein. 5. Heart rate and breathing rate increased during swimming and then decreased when swimming ceased. 6. Some possible mechanisms regulating heart and breathing rates are discussed.


Author(s):  
Abinand Manorama ◽  
Tamara Reid Bush

Pressure ulcers have been a concern in healthcare settings, with more than 50% of bedridden or wheelchair-bound patients being affected [1]. Pressure ulcers typically occur on a region of the body that experiences forces from an external structure (e.g. bed, wheelchair). Researchers believe that such forces cause a decrease in blood flow, which results in tissue necrosis, causing pressure ulcers [2].


1959 ◽  
Vol 197 (5) ◽  
pp. 1111-1114 ◽  
Author(s):  
Matthew N. Levy

Temperature was diminished in a stepwise fashion in the isolated kidney of the dog perfused from a peripheral artery of the original, normothermic animal. Decreased temperature resulted in an appreciable reduction of renal blood flow at constant arterial blood pressure. Increased blood viscosity and vasoconstriction were both responsible for this reduction of flow. Hypothermia also resulted in a reduction in arteriovenous oxygen difference which was roughly proportional to the centigrade temperature. Furthermore, hypothermia exerted a marked but reversible depression of the rate of oxidative metabolism. This effect was relatively more severe than the changes for the body as a whole at equivalent temperatures reported by other investigators.


1842 ◽  
Vol 132 ◽  
pp. 81-85 ◽  

The contents of the thoracic duct in the human subject having never been obtained in sufficient quantity for the purposes of chemical analysis, I resolved to avail myself of an opportunity which lately presented itself in the execution of a criminal at the Old Bailey. Through the kindness of Messrs. Macmurdo and Holding, the medical officers of Newgate, and with the assistance of my friends Mr. Hilton and Mr. Samuel Lane, I was enabled to commence operating upon the body one hour and a quarter after death, and before it had become cold, although the thermometer stood considerably below 32° Fahr., and the body had been exposed on the scaffold during one hour. The subject was muscular and of the middle height, and the prisoner had not become emaciated during his confinement in jail. On the evening preceding his execution, he had partaken of some supper, consisting of about 2 oz. of bread and 4 oz. of meat; and the next morning, he drank two cups of tea, and ate a piece of toast made from the quarter of a round of a quartern loaf, and about a quarter of an inch in thick­ness. This breakfast was taken at seven o’clock A. M., one hour before death. He swallowed a glass of wine just before mounting the scaffold.


2002 ◽  
Vol 41 (04) ◽  
pp. 245-260 ◽  
Author(s):  
C. Rosse ◽  
J. F. Brinkley

Summary Objectives: Survey current work primarily funded by the US Human Brain Project (HBP) that involves substantial use of images. Organize this work around a framework based on the physical organization of the body. Methods: Pointers to individual research efforts were obtained through the HBP home page as well as personal contacts from HBP annual meetings. References from these sources were followed to find closely related work. The individual research efforts were then studied and characterized. Results: The subject of the review is the intersection of neuroinformatics (information about the brain), imaging informatics (information about images), and structural informatics (information about the physical structure of the body). Of the 30 funded projects currently listed on the HBP web site, at least 22 make heavy use of images. These projects are described in terms of broad categories of structural imaging, functional imaging, and image-based brain information systems. Conclusions: Understanding the most complex entity known (the brain) gives rise to many interesting and difficult problems in informatics and computer science. Although much progress has been made by HBP and other neuroinformatics researchers, a great many problems remain that will require substantial informatics research efforts. Thus, the HPB can and should be seen as an excellent driving application area for biomedical informatics research.


1975 ◽  
Vol 38 (6) ◽  
pp. 1143-1145 ◽  
Author(s):  
R. W. Krutz ◽  
S. A. Rositano ◽  
R. E. Mancini

Two objective methods and one subjective method for measuring +Gz tolerance (inertial vector in a head-to-foot direction) were compared on the human centrifuge. Direct eye-level blood pressure (Pa), blood flow velocity in the superficial temporal artery (Qta), and subjective visual symptoms were used to determine tolerance to rapid onset acceleration (1 G/s) on the USAFSAM human centrifuge. Seven “relaxed” subjects with extensive centrifuge experience were exposed to gradually increasing +Gz plateaus until the subject reported 100% loss of peripheral centrifuge gondola lights (PLL) and 50% loss of central light (CLD); viz., blackout. Zero forward Qta occurred 6 s (range 4–9 s) before subjective blackout and when mean eye-level blood pressure had reached 20 +/- 1 mmHg (SE). The results of this study indicate that flow changes in the superficial temporal artery reflect flow changes in the retinal circulation during +Gz stress.


1977 ◽  
Vol 232 (6) ◽  
pp. H652-H656
Author(s):  
W. W. Lautt

Acute denervation of the liver did not result in changes of oxygen uptake or hemodynamics in the intact liver of the cat. Stimulation of the hepatic nerves resulted in a marked reduction of vascular conductance of the hepatic artery and portal vein (intrahepatic) resulting in almost complete cessation of arterial flow and increased portal blood pressure. The hepatic artery showed a more complete escape from the neurogenic vasoconstriction than did the portal vein. During the stable "escape phase" oxygen delivery was 86% of control, but hepatic extraction of oxygen increased so that oxygen uptake was not altered from control values. The return of oxygen consumption to normal during nerve stimulation suggests that redistribution of hepatic blood flow did not occur. In spite of arterial and portal venous blood pressure changes and changes in gut conductance, oxygen extraction of the gut did not change.


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