COMPARISON OF ANTIHYPERTENSIVE EFFECT OF MOXONIDINE VERSUS CLONIDINE IN RENAL FAILURE PATIENTS.

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
Blood Flow ◽  
Blood Vessel ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Antihypertensive Effect ◽  
The Body ◽  
Ability To Work ◽  
Blood Flows

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.

Buckling Behavior of Arteries Under Torsion

2011 ◽  
Author(s):  
Justin R. Garcia ◽  
Shawn D. Lamm ◽  
Hai-Chao Han
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Atherosclerotic Plaque ◽  
Vascular Grafts ◽  
Vascular Diseases ◽  
The Body ◽  
Buckling Behavior ◽  
Surgical Implantation

Arterial tortuosity is a phenomenon which is observed throughout the body and is associated with aging, diabetes, high blood pressure, and other vascular diseases [1]. Tortuous arteries significantly hinder blood flow which may lead to the development of atherosclerotic plaque buildup [2]. Blood vessels may also become twisted or demonstrate 3-D tortuous shapes when subject to large twist deformations such as during surgical implantation of vascular grafts, propeller flap procedures, stent-artery interactions, and sudden movements of the neck or limbs [4–6]. However, the twisting behavior of arteries is poorly understood.

Edema, Fainting, and Strokes

2021 ◽  
pp. 216-240
Author(s):  
Graham Mitchell
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Fluid Pressure ◽  
Basement Membranes ◽  
Tissue Pressure ◽  
Efficient Mechanisms ◽  
The Brain ◽  
Mediated Reduction

High blood pressure in humans is often associated with heart failure, edema, strokes, and episodes of fainting. Giraffes never show these. Edema, the abnormal collection of fluid in the lower legs, is prevented in giraffes by a combination of thick basement membranes of capillary blood vessels, which probably reduce their permeability to proteins, a very high tissue pressure that resists flow of fluid out of capillaries, and efficient mechanisms for returning blood to the heart. Fainting occurs when blood flow (and thus oxygen and glucose supply) to the brain is reduced. When a giraffe lifts its head after drinking water there is a sudden reduction of blood flow to the head, and fainting should result. Fainting is avoided because the blood flow that remains is diverted completely to the brain by a unique arrangement of blood vessels and nerves, and by structures that maintain the perfusion pressure of the blood flowing through the brain. Strokes can be caused by rupture of small blood vessels in the brain when they are exposed to high blood pressure of the kind reached in the head of a giraffe when it drinks surface water. Rupture of brain blood vessels is prevented in giraffes by mechanisms that reduce pressure. The posture adopted while drinking, baroreceptor-mediated reduction in cardiac output, the effects of the carotid rete, diversion of blood away from the brain, an increase in cerebrospinal fluid pressure, and passive and active constriction of blood vessels, all contribute.

scholarly journals INFLUENCE OF AGE AND GENDER ON THE STRENGTH OF BLOOD VESSELS

2016 ◽  
Vol 4 ◽  
pp. 719-726
Author(s):  
Zyta Kuzborska
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Blood Vessel ◽  
Flow Velocity ◽  
Blood Vessels ◽  
Blood Flow Velocity ◽  
Vessel Wall ◽  
Blood Vessel Wall ◽  
Critical Stresses ◽  
And Gender

This article examines the effects of cardiovascular diseases that alter the diameter, wall thickness, and length of blood vessels. Depending on form and size of the damage, blood flow velocity, blood pressure, and stresses are affected in areas of diseased blood vessels. Through stimulating the deviations in the geometric shape of a blood-vessel wall, local blood pressure and stresses can arise from flow variation of blood vessels. This rise affects the blood-vessel wall and causes critical stresses likely to produce fissures in the blood vessels. It was found, that blood vessel pathology could cause blood flow velocity to increase up to 2.2 times and local blood pressure up to 3.4 times, and that human aging may have a significant influence on blood-vessel strength.

Living Well to Keep Your Pressure Down

EDIS ◽  
2017 ◽  
Vol 2017 (6) ◽  
Author(s):  
Linda B. Bobroff
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Health Problems ◽  
Fact Sheet ◽  
Living Well ◽  
Heart Work ◽  
Major Revision ◽  
Reduce Risk

High blood pressure, or hypertension, can cause serious health problems. It makes your heart work harder and can damage your blood vessels even if you feel okay. Everyone should have their blood pressure checked regularly. If you have certain risk factors, you are more likely to have high blood pressure. This 6-page fact sheet is a major revision that discusses risk factors and ways to reduce risk.

Maximal vascular leg conductance in trained and untrained men

1987 ◽  
Vol 62 (2) ◽  
pp. 606-610 ◽  
Author(s):  
P. G. Snell ◽  
W. H. Martin ◽  
J. C. Buckey ◽  
C. G. Blomqvist
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Oxygen Uptake ◽  
Maximal Oxygen Uptake ◽  
Reactive Hyperemia ◽  
Venous Occlusion ◽  
Vascular Conductance ◽  
Blood Flows ◽  
Arterial Blood ◽  
Sedentary Subjects

Lower leg blood flow and vascular conductance were studied and related to maximal oxygen uptake in 15 sedentary men (28.5 +/- 1.2 yr, mean +/- SE) and 11 endurance-trained men (30.5 +/- 2.0 yr). Blood flows were obtained at rest and during reactive hyperemia produced by ischemic exercise to fatigue. Vascular conductance was computed from blood flow measured by venous occlusion plethysmography, and mean arterial blood pressure was determined by auscultation of the brachial artery. Resting blood flow and mean arterial pressure were similar in both groups (combined mean, 3.0 ml X min-1 X 100 ml-1 and 88.2 mmHg). After ischemic exercise, blood flows were 29- and 19-fold higher (P less than 0.001) than rest in trained (83.3 +/- 3.8 ml X min-1 X 100 ml-1) and sedentary subjects (61.5 +/- 2.3 ml X min-1 X 100 ml-1), respectively. Blood pressure and heart rate were only slightly elevated in both groups. Maximal vascular conductance was significantly higher (P less than 0.001) in the trained compared with the sedentary subjects. The correlation coefficients for maximal oxygen uptake vs. vascular conductance were 0.81 (trained) and 0.45 (sedentary). These data suggest that physical training increases the capacity for vasodilation in active limbs and also enables the trained individual to utilize a larger fraction of maximal vascular conductance than the sedentary subject.

Oxygen consumption and blood flow in the hypothermic, perfused kidney

1959 ◽  
Vol 197 (5) ◽  
pp. 1111-1114 ◽  
Author(s):  
Matthew N. Levy
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Oxygen Consumption ◽  
Blood Viscosity ◽  
The Body ◽  
Peripheral Artery ◽  
Isolated Kidney ◽  
Arterial Blood ◽  
Oxygen Difference ◽  
Appreciable Reduction

Temperature was diminished in a stepwise fashion in the isolated kidney of the dog perfused from a peripheral artery of the original, normothermic animal. Decreased temperature resulted in an appreciable reduction of renal blood flow at constant arterial blood pressure. Increased blood viscosity and vasoconstriction were both responsible for this reduction of flow. Hypothermia also resulted in a reduction in arteriovenous oxygen difference which was roughly proportional to the centigrade temperature. Furthermore, hypothermia exerted a marked but reversible depression of the rate of oxidative metabolism. This effect was relatively more severe than the changes for the body as a whole at equivalent temperatures reported by other investigators.

scholarly journals Real-Time Longitudinal Evaluation of Tumor Blood Vessels Using a Compact Preclinical Fluorescence Imaging System

Biosensors ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 471
Author(s):  
Hoibin Jeong ◽  
Song-Rae Kim ◽  
Yujung Kang ◽  
Huisu Kim ◽  
Seo-Young Kim ◽  
...  
Keyword(s):  
Blood Flow ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Real Time ◽  
Tumor Angiogenesis ◽  
Imaging System ◽  
Angiogenesis Inhibitors ◽  
Laboratory Unit ◽  
Vessel Volume ◽  
Tumor Blood Vessels

Tumor angiogenesis is enhanced in all types of tumors to supply oxygen and nutrients for their growth and metastasis. With the development of anti-angiogenic drugs, the importance of technology that closely monitors tumor angiogenesis has also been emerging. However, to date, the technology for observing blood vessels requires specialized skills with expensive equipment, thereby limiting its applicability only to the laboratory setting. Here, we used a preclinical optical imaging system for small animals and, for the first time, observed, in real time, the entire process of blood vessel development in tumor-bearing mice injected with indocyanine green. Time-lapse sequential imaging revealed blood vessel volume and blood flow dynamics on a microscopic scale. Upon analyzing fluorescence dynamics at each stage of tumor progression, vessel volume and blood flow were found to increase as the tumor developed. Conversely, these vascular parameters decreased when the mice were treated with angiogenesis inhibitors, which suggests that the effects of drugs targeting angiogenesis can be rapidly and easily screened. The results of this study may help evaluate the efficacy of angiogenesis-targeting drugs by facilitating the observation of tumor blood vessels easily in a laboratory unit without large and complex equipment.

scholarly journals A CASE STUDY ON ESSENTIAL HYPERTENSION MANAGING THROUGH AYURVEDA W.S.R. RAKTAGATA VYAN VAISHAMYA

2021 ◽  
Vol p5 (4) ◽  
pp. 2965-2968
Author(s):  
Ruhi Zahir ◽  
Iqbal Khan
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
Risk Factor ◽  
Essential Hypertension ◽  
Cardiovascular Diseases ◽  
High Blood Pressure ◽  
Direct Reference ◽  
Major Risk Factor ◽  
End Stage

Essential hypertension is high blood pressure that doesn't have any known etiopathology. Most of sufferers (85%) are asymptomatic and as per available reports, in more than 95% cases of hypertension under lying cause is not found. It is estimated that 600 million people are affected worldwide. Hypertension is a major risk factor for the development of cardiovascular diseases (CVD). Its impact is greatest on stroke, MI and end stage is renal failure as it’s known as a Silent Killer. Hence there is no direct reference of hypertension in Ayurvedic classics by name as well as by its path physiological views. Many works have been carried out on hypertension to evaluate the perfect diagnosis and mode of treatment on the basis of Different nomenclatures also have been adopted by Ayurveda experts like Raktagata Vata, Raktagata Vyana Vaisamya, Uccha Rakta Chapa, Raktavrita Vata, Siragata Vata etc. Keywords: Essential hypertension, Raktagata Vyana Vaisamya, Uccha Rakta Chapa, Cardiovascular diseases, Silent Killer.

AN EFFECT OF REDUCED BAROMETRIC PRESSURE ON THE PERIPHERAL CIRCULATION

1957 ◽  
Vol 35 (10) ◽  
pp. 777-783
Author(s):  
F. Girling ◽  
F. A. Sunahara
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Forearm Blood Flow ◽  
Human Subjects ◽  
Arterial Oxygen Saturation ◽  
Barometric Pressure ◽  
Peripheral Circulation ◽  
Arterial Oxygen ◽  
Blood Flows ◽  
The Past

Several groups of investigators have noted in the past that exposure to a reduced barometric pressure results in a decrease in peripheral blood flow.In the present study human subjects were exposed to a pressure of 225 mm. Hg with maintenace of arterial oxygen saturation, and forearm and hand blood flows were measured plethysmographically. Forearm blood flow was not affected by the exposure whereas hand blood flow was reduced in all subjects. Blood pressure and heart rate were also measured and showed no change during the experiment.

Anaesthesia of the patient with chronic kidney disease

2020 ◽  
Vol 25 (11) ◽  
pp. 268-276
Author(s):  
Oscar Bautista Díaz-Delgado ◽  
Briony Alderson
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Renal Failure ◽  
Cardiac Output ◽  
Kidney Disease ◽  
The Body ◽  
Renal Physiology ◽  
Successful Management ◽  
Emergency Procedures ◽  
Routine Procedures

Chronic kidney disease is common, particularly in geriatric animals. General anaesthesia is usually required for routine procedures (dental prophylaxis, ovariohysterectomy or castration) and emergency procedures, which may have profound effects on the body, especially on cardiac output, subsequent blood pressure and on the perfusion of different vital organs. It is essential to understand the effects of renal dysfunction on the patient, as well as the effects that anaesthesia and surgery may have on the kidneys. The understanding of renal physiology, along with the effect of drug choices, is key to successful management of chronic renal failure.

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