Incidence and oncologic outcome of renal cell carcinoma in hemodialysis patients detected by annual computed tomography (CT) screening.

2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 426-426
Author(s):  
Shingo Hatakeyama ◽  
Hayato Yamamoto ◽  
Takahiro Yoneyama ◽  
Yasuhiro Hashimoto ◽  
Takuya Koie ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Dysfunction ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Normal Kidney ◽  
Cancer Specific Survival ◽  
Annual Screening ◽  
Function Group

426 Background: Patients with maintenance hemodialysis (HD) have been recognized as a high risk group for cancer. The aim of this study was to verify the incidence and oncological outcomes of patients on maintenance hemodialysis with renal cell carcinoma (RCC) compared with RCC patients without renal dysfunction. Methods: We have been carried out annual screening for renal mass for the hemodialysis patients.The oncological outcome of pT1N0M0 RCC detected by annual screening of CT imaging were retrospectively reviewed in 1217 patients with HD between January 2002 and December 2010 at Oyokyo kidney Research Institute and Hirosaki University Hospital, Hirosaki, Japan. Overall and cancer specific survival was compared with age matched 106 of pT1N0M0 RCC patients without renal dysfunction who performed radical nephrectomy at the same periods. Results: Among the hemodialysis patients, 14 RCCs were incidentally detected by screening CT examinations and RCC detection rate in HD patients was 0.27% per year. Total 119 pT1N0M0 RCC patients (13 with HD group, 106 normal kidney function group) were incidentally detected by regular abdominal CT imaging without symptoms. There were no significant differences on age and gender between HD and normal kidney function group. Cancer specific survival after tumor diagnosis was not different, but overall survivals were significantly superior in patients without renal dysfunction compared to those with chronic renal failure (P < 0.0001). Cancer specific and Overall 5-year survival was 95% and 96% in patients without renal dysfunction, 92% and 54% in those with chronic renal failure. Conclusions: There was no significant difference in cancer specific survival of pT1 RCC between the two groups. However, overall survival was significantly worse in HD patients. Oncological effectiveness of annual CT screening for the HD patients was not evident in the present retrospective study.

Propranolol-Associated Hypoglycemia in Patients on Maintenance Hemodialysis

1981 ◽  
Vol 4 (3) ◽  
pp. 130-134 ◽  
Author(s):  
A. Zarate ◽  
M. Gelfand ◽  
A. Novello ◽  
J. Knepshield ◽  
H.G. Preuss
Keyword(s):  
Renal Failure ◽  
Cardiac Arrest ◽  
Chronic Renal Failure ◽  
Severe Hypoglycemia ◽  
Signs And Symptoms ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Life Threatening ◽  
Insulin Use

Propranolol is widely employed in hemodialysis patients for the control of renin-dependent hypertension. Infrequent reports have linked hypoglycemia and propranolol, especially in complex situations such as malnutrition, anesthesia, and excessive insulin use. Three patients on maintenance hemodialysis taking propranolol developed severe hypoglycemia resulting in cardiac arrest. The life-threatening hypoglycemia occurred without apparent precipitating cause and unaccompanied by the classical signs and symptoms of hypoglycemia. These three cases suggest that propranolol in a setting of chronic renal failure and dialysis may bring about severe hypoglycemia, a complication previously unsuspected.

scholarly journals The Effect of Discontinuation of Angiotensin-II Receptor Blocker on Therapeutic Effect of Synthetic Erythropoietin on Anemia Modification in Hemodialysis Patients

2019 ◽  
Vol 25 (3) ◽  
pp. 230-254
Author(s):  
Farid Reza Ejlali ◽  
◽  
Mahmood Reza Khazaei ◽  
Zahra Mostafavian ◽  
Jalil Moshari ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Hemodialysis Patients ◽  
Hemoglobin Level ◽  
Maintenance Hemodialysis ◽  
Angiotensin Ii Receptor Blocker ◽  
Angiotensin Ii Receptor ◽  
Before And After ◽  
In The Beginning

Aims The aim of this study was to evaluate the effect of discontinuation of losartan in response to synthetic erythropoietin therapy on hemoglobin level in patients on maintenance hemodialysis. Methods & Materials This study was a pre-and post-interventional clinical trial. The population of the study was hemodialysis patients with chronic renal failure. In the beginning of the study, and three months after removal of losartan, the patients’ hemoglobin changes were compared. Findings Hemoglobin was significantly increased at the end of the study in all patients (from 10.90±1.66 at the beginning of the study to 11.37±1.42g/dl at the end of 3 months, P=0.046). No significant changes were seen in the hemoglobin level before and after intervention between patients according age, sex, and duration of the disease. Conclusion There was a significant increase in hemoglobin level at the end of study after losartan discontinuation. But this increase did not have a significant relationship with patient’s age, sex as well as the duration of the disease.

scholarly journals Renal cell carcinoma in a patient with chronic renal failure who avoided postoperative maintenance hemodialysis by successful partial nephrectomy

2005 ◽  
Vol 38 (7) ◽  
pp. 1351-1354
Author(s):  
Manabu T. Moriyama ◽  
Kousuke Tokunaga ◽  
Katsuhito Miyazawa ◽  
Tatsuro Tanaka ◽  
Koji Suzuki ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Cell Carcinoma ◽  
Partial Nephrectomy ◽  
Renal Cell ◽  
Maintenance Hemodialysis

Cation-exchange chromatography of guanidine derivatives in plasma of patients with chronic renal failure.

1976 ◽  
Vol 22 (2) ◽  
pp. 240-242 ◽  
Author(s):  
G Perez ◽  
A Rey ◽  
M Micklus ◽  
I Stein
Keyword(s):  
Renal Failure ◽  
Liquid Chromatography ◽  
Chronic Renal Failure ◽  
Accurate Method ◽  
Hemodialysis Patients ◽  
Exchange Chromatography ◽  
Maintenance Hemodialysis ◽  
Healthy Controls ◽  
Cation Exchange Chromatography ◽  
Guanidine Derivatives

Abstract Guanidine derivatives are suspected of contributing to the toxic manifestations of uremia. We describe a method for measurement of guanidine derivatives in 5-ml samples of plasma by liquid chromatography. Concentrations of guanidinosuccinate and guanidinobutyrate in plasma were significantly increased both in undialyzed patients with chronic renal failure (5.54 +/- 0.94 and 17.5 +/- 4.07 mg/liter) and those undergoing maintenance hemodialysis (2.35 +/- 0.41 and 19.4 +/- 3.99 mg/liter) when compared to healthy controls (less than 0.4 and 1.0 +/- 0.3 mg/liter, respectively). Creatine and guanidinoacetate concentrations tended to be higher in hemodialysis patients and lower in the undialyzed group of patients with chronic renal failure. This procedure provides a rapid, sensitive, and accurate method for the study of guanidine metabolism in persons with uremia.

Summer Camp Hemodialysis for Children With Chronic Renal Failure

PEDIATRICS ◽  
1977 ◽  
Vol 60 (1) ◽  
pp. 46-50
Author(s):  
William A. Primack ◽  
Ira Greifer
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Medical Treatment ◽  
Summer Camp ◽  
Maintenance Hemodialysis ◽  
Self Confidence ◽  
Self Image ◽  
Hemodialysis Unit ◽  
Pediatric Hemodialysis ◽  
Satellite Unit

A hemodialysis unit was established at a rural summer camp for children. Required medical treatment was planned so as to interfere as little as possible with normal camp programs. Campers who require dialysis were mixed fully into the population of normal campers. Twenty-two children participated during the first summer of operation. Our experience indicates that children on maintenance hemodialysis can be integrated with normal peers in a recreational program and can improve their self-image and self-confidence. The program also demonstrates that chronic pediatric hemodialysis can be safely performed in a rural satellite unit.

Conjunctival and Corneal Changes in Chronic Renal Failure Patients Treated with Maintenance Hemodialysis

1995 ◽  
Vol 209 (1) ◽  
pp. 14-16 ◽  
Author(s):  
Dušica Pahor ◽  
Radovan Hojs ◽  
Bojan Gračner
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Maintenance Hemodialysis
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