Gene Knockout Technology and the Host Response to Endotoxin: Role of CD14 and Other Inflammatory Mediators

2020 ◽  
pp. 781-793
Author(s):  
Sanna M. Goyert
Keyword(s):  
Inflammatory Mediators ◽  
Host Response ◽  
Gene Knockout ◽  
Knockout Technology ◽  
Gene Knockout Technology

THE EFFECT OF ABA AND IAA PHYTOHORMONES ON THE REDUCING SUGARS AND ENDOGENOUS PHYTOHORMONES CONTENT OF COTTON PLANT UNDER SALIFICATION

1970 ◽  
pp. 57-60
Author(s):  
K. M. Kuldoshova ◽  
А. А. Akhunov ◽  
N. R. Khashimova ◽  
D. T. Babaeva ◽  
М. I. Nurmatova
Keyword(s):  
Salt Stress ◽  
Environmental Factors ◽  
Reducing Sugars ◽  
Prolonged Exposure ◽  
Gene Knockout ◽  
Cotton Variety ◽  
Exogenous Aba ◽  
Endogenous Phytohormones ◽  
Knockout Technology ◽  
Gene Knockout Technology

This article investigates the effect of exogenous phytohormones ABA and IAA on the content of reducing sugars and endogenous phytohormones in cotton seedlings of varieties Porlok-4, obtained on the basis of gene knockout technology and a marker of associated breeding - Ravnak-1. Exogenous phytohormones (ABA and IAA) can significantly change the level of cotton resistance to unfavorable environmental factors. Under the action of exogenous ABA causes an increase of cotton resistance to salinity. Biotechnological cotton variety Ravnak-1 showed sensitivity to prolonged exposure to salinity in combination with phytohormones, increasing the content of reducing sugars and endogenous phytohormones, depending on the duration of salt stress. In the Porlok-4 variety, under the influence of salinity, the content of reducing sugars and endogenous phytohormones had an insignificant increase, due to the inherent adaptive capacity of the variety. The conducted studies allow us to conclude that phytohormones are actively involved in the formation of cotton resistance to the action of unfavorable environmental factors of an abiotic nature.

Progress in xenotransplantation following the introduction of gene-knockout technology

2007 ◽  
Vol 20 (2) ◽  
Author(s):  
Hao-Chih Tai ◽  
Mohamed Ezzelarab ◽  
Hidetaka Hara ◽  
David Ayares ◽  
David K.C. Cooper
Keyword(s):  
Gene Knockout ◽  
Knockout Technology ◽  
Gene Knockout Technology

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis

2011 ◽  
Vol 11 (1) ◽  
pp. 130-133
Author(s):  
Astra Zviedre ◽  
Arnis Engelis ◽  
Mohit Kakar ◽  
Aigars Pētersons
Keyword(s):  
Early Detection ◽  
Acute Appendicitis ◽  
Inflammatory Mediators ◽  
Potential Role ◽  
Clinical Symptoms ◽  
Future Research ◽  
Mesenteric Lymphadenitis ◽  
Proper Diagnosis ◽  
Near Future

Potential Role of Cytokines in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis Although, AAP and AML have different etiological factors, clinical symptoms are very much similar but treatment tactics in both the disease differ a lot. In case of AML, treatment is more conservative and does not require hospitalization while in case of AAP immediate hospitalization and maybe further surgery can be mandatory. With the identification of group of cytokines serum inflammatory mediators IL-8, IL-10, IL-12[p70], IL-17, TNF-a and MCP-1, it is believed early and proper diagnosis of AAP in the near future. Research of cytokines-serum inflammatory mediators has opened new opportunities for an early detection and differentiation of these two diseases in children.

From Genesis To Revelation: The Role Of Inflammatory Mediators In Chronic Respiratory Diseases And Their Control By Nucleic Acid-Based Drugs

2016 ◽  
Vol 13 (999) ◽  
pp. 1-1 ◽  
Author(s):  
Sante Di Gioia ◽  
Carla Sardo ◽  
Stefano Castellani ◽  
Barbara Porsio ◽  
Giuliana Belgiovine ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Inflammatory Mediators ◽  
Respiratory Diseases ◽  
Chronic Respiratory Diseases
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