Drug Synergism and Dose-Effect Data Analysis

Author(s):  
Ronald J. Tallarida
Analgesia ◽  
1998 ◽  
Vol 3 (5) ◽  
pp. 297-305 ◽  
Author(s):  
Jeffrey D. McCary ◽  
Ronald J. Tallarida

Author(s):  
A. Fedoruk ◽  
◽  
V. Gurvich

Abstract: The assessment experience of the occupational health risk at the enterprises of mining and metallurgical complex of the Sverdlovsk region has revealed the presence of key challenges. They are related to an impartial evaluation of the predicted and realized risks. These include underestimation of factors of the working environment and process at the stage of identification, monitoring management and evaluation of results. Additionally, there is no data analysis on the health status of workers, including the estimated incidence of temporary incapacity for work. It is suggested to develop a unified preventive system (occupational health service) at the enterprises. It will be possible to form an appropriate database regarding the real situation of working conditions and the health of workers. This system will also establish cause-and-effect relationships and dose-effect dependencies of diseases. Additionally, it will be enforceable to identify the probability of occupational and industrial-related diseases at the group and individual levels.


2019 ◽  
Vol 3 (2) ◽  
pp. 81
Author(s):  
Joy Maranatha Tarigan ◽  
Tritjahjo Danny Soesilo ◽  
Sapto Irawan

Social media has become one part of the society, social media users, especially students, make everyone communicate with each other and share information. This research aimed to identifying the influence of using social media (instagram) on academic achievement. The subjects of the study were the 2015 SWCU FKIP BK students. The data analysis method used was path analysis. Based on data analysis, the results obtained sig = 0.711> 0.05 so that it can be said that there is no significant effect. Data values t = 0.373 < 2.002 and the value of R Square is 0.002, according the results, the concluded that there is no significant influence between the using of social media (instagram) on academic performance because of the influence of 0.2% and 99.8% influenced by other factors not explained in this research.


1985 ◽  
Vol 1 (4) ◽  
pp. 23-41 ◽  
Author(s):  
Michael L. Dourson ◽  
Richard C. Hertzberg ◽  
Rolf Hartung ◽  
Karen Blackburn

This paper describes two general methods for estimating ADIs that circumvent some of the limitations inherent in current approaches. The first method is based on a graphic presentation of toxicity data and is also shown to be useful for estimating acceptable intakes for durations of toxicant exposure other than the entire lifetime. The second method uses dose-response or dose-effect data to calculate lower CLs on the dose rate associated with specified response or effect levels. These approaches should lead to firmer, better established ADIs through increased use of the entire spectrum of toxicity data.


2002 ◽  
Vol 234 (3) ◽  
pp. 872-876 ◽  
Author(s):  
B. Arnaudov ◽  
T. Paskova ◽  
S. Evtimova ◽  
M. Heuken ◽  
B. Monemar

2003 ◽  
Vol 67 (4) ◽  
Author(s):  
B. Arnaudov ◽  
T. Paskova ◽  
S. Evtimova ◽  
E. Valcheva ◽  
M. Heuken ◽  
...  

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