Brazilian Bryophytes and Pteridophytes as Rich Sources of Medicinal Compounds

2019 ◽  
pp. 135-172
Author(s):  
Adaíses Simone Maciel-Silva ◽  
Lucas Vieira Lima
Keyword(s):  
Medicinal Compounds

Potential Medicinal Compounds from Liverworts

Planta Medica ◽  
2012 ◽  
Vol 78 (05) ◽  
Author(s):  
Y Asakawa
Keyword(s):  
Medicinal Compounds

Molecular Docking of Traditional Chinese Medicinal Compounds Against Dengue Virus NS3 Protease and NS3 Helicase

2020 ◽  
Author(s):  
Jewel Mae S. Cadiz ◽  
Christine Joy U. Susana ◽  
Marla A. Endriga ◽  
Enrique Jose L. Frio
Keyword(s):  
Molecular Docking ◽  
Dengue Virus ◽  
Medicinal Compounds ◽  
Ns3 Protease

The physicochemical and DNA binding studies of some medicinal compounds in solutions

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Abbas Khan ◽  
Naila ◽  
Muhammad Humayun ◽  
Muhammad Sufaid Khan ◽  
Luqman Ali Shah ◽  
...  
Keyword(s):  
Flow Behavior ◽  
Aqueous Media ◽  
Research Work ◽  
Binding Constants ◽  
Physicochemical Study ◽  
Solution Temperature ◽  
Binding Studies ◽  
Experimental Conditions ◽  
Medicinal Compounds ◽  
Association Behavior

Abstract To understand the expected mode of action, the physicochemical study on the solution properties of medicinal compounds and their interaction with deoxyribonucleic acid (DNA), under varying experimental conditions, is of prime importance. The present research work illustrates the physicochemical study and interaction of certain medicinal compounds such as; Levofloxacin, Ciprofloxacin, and Ibuprofen with DNA. Density, viscosity and surface tension measurements have been performed in order to determine, in a systematic manner, the physicochemical, volumetric and thermodynamic properties of these compounds; and most of these parameters have shown different behavior with varying concentration of solution, temperature of the medium and chemical nature/structure of the compound. In addition, these drugs showed a spontaneous surface-active and association behavior in aqueous solutions. The flow behavior, surface properties, volumetric behavior and solute–solvent interaction of these drugs were prominently influenced by experimental variables and addition of DNA to their solutions. UV–Visible spectroscopy was also used to examine the interaction of these drugs with DNA in aqueous media in detail. Calculated values of binding constants (Kb) for all complexes of drug-DNA are positive, indicating a fruitful binding process. It is seen that a smaller Kb value reflects weaker binding of the drug with DNA and vise versa. Due to the difference in the chemical structure of drugs the values of binding constant are different for various drug-DNA complexes and follow the order Kb(Levofloxacin-DNA) > Kb(Ciprofloxacin-DNA) > Kb(Ibuprofen-DNA). On the basis of spectral changes and Kb it can be said that the binding of all these drugs with DNA may be of physicochemical nature and the dominating binding force be of hydrogen bonding between oxygen of drugs and hydrogen of DNA units and the drug having more oxygen atoms showed stronger binding ability. The data further suggest a limited possibility of chemical type attachment of these drugs with DNA.

scholarly journals A database for the predicted pharmacophoric features of medicinal compounds

2011 ◽  
Vol 6 (4) ◽  
pp. 167-168 ◽  
Author(s):  
Pitchai Daisy ◽  
Sanjeev Kumar Singh ◽  
Periyasamy Vijayalakshmi ◽  
Chandrabose Selvaraj ◽  
Manikkam Rajalakshmi ◽  
...  
Keyword(s):  
Medicinal Compounds

scholarly journals Обмін білково-вуглеводних сполук у сироватці крові й синовіальній рідині за різних методів лікування та асептичних артритів у коней

2013 ◽  
pp. 84-86
Author(s):  
В. Й. Іздепський ◽  
А. В. Іздепський
Keyword(s):  
Synovial Fluid ◽  
Sialic Acids ◽  
Rapid Exchange ◽  
Medicinal Compounds ◽  
Comparative Aspect

Висвітлюються особливості обміну білково-вуглеводних сполук у сироватці крові та синовіальній рідині за різних методів лікування асептичних артритів у коней. У порівняльному аспекті досліджено ефективність внутрішньосуґлобових ін’єкцій різних лікувальних сумішей, що містять протизапальний та анестезувальний компоненти. Встановлено, що використання мовалісу з трифузолом сприяє швидкому відновленню обміну сіалових кислот і серомукоїдів як у сироватці крові, такі в синовіальній рідині у порівнянні з дипроспаном. Results highlight features of exchange of protein containing compounds in serum and synovial fluid at various treatments of aseptic arthritis in horses. In comparative aspect the efficacy of intraarticular injections of various medicinal compounds containing anesthetic and antiinflammatory components is studied. It was found that the use of Movalis in combination with trifuzolom promotes rapid exchange recovery seromucoid sialic acids in serum and synovial fluid in comparison with diprospanom.

scholarly journals Therapeutic potential of seaweeds

2021 ◽  
Vol 10 (5) ◽  
pp. 591
Author(s):  
Rajeev Goel ◽  
Tushar Saini ◽  
Binny Mahendru
Keyword(s):  
Clinical Trials ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Coastal Regions ◽  
Medicinal Compounds ◽  
Medicinal Properties ◽  
Low Incidence ◽  
Marine Nutrients

Seaweeds in general are known to contribute to the maintenance of health through their nutritional and medicinal properties and are served in soups and salads, cooked with grains, legumes or miso-soup broth, vegetable pies, stews and even consumed dried. The medicinal properties of seaweeds or vegetables have long been known in many cultures of people particularly those living in the coastal regions who are consuming these from centuries. Traditional Chinese dietotherapy (TCD) makes good use of natural marine nutrients and food to preserve health. Koreans wrap their bodies in seaweeds to get rid of deadly body toxins and Japanese who eat large quantities of seaweeds have very low incidence of cancers. The compounds with diverse biological activities such as antioxidant, antiviral, antifungal, antineoplastic, antimicrobial etc. have been isolated from the flora in the sea. A score of these bio-medicinal compounds are in different stages of clinical trials & analysis and are the focus of this article. 

scholarly journals Light-sensitive medicinal compounds – the actual review of studies and strategies in proceedings

2019 ◽  
Vol 75 (10) ◽  
pp. 575-583
Author(s):  
Marzena Jamrógiewicz ◽  
Aneta Karczewska-Kaliszak ◽  
Karolina Milewska
Keyword(s):  
Medicinal Compounds
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