scholarly journals 137 MATHEMATICAL APPROACH TO THE SELECTION OF THE BEST DIAGNOSTIC PROCEDURES IN NEONATAL SEPTICAEMIA

1986 ◽  
Vol 20 (10) ◽  
pp. 1057-1057
Author(s):  
Z A Mitkowska ◽  
J J Pietrzyk ◽  
J Pryjma ◽  
B S Rózański
Keyword(s):  
Diagnostic Procedures ◽  
Mathematical Approach ◽  
Neonatal Septicaemia ◽  
Selection Of

Selection of Diagnostic Procedures

CHEST Journal ◽  
1979 ◽  
Vol 75 (2) ◽  
pp. 111-112
Author(s):  
E. Garner King
Keyword(s):  
Diagnostic Procedures ◽  
Selection Of

Performance Analysis of Twin-Spool Water Injected Gas Turbines Using Adaptive Modeling

2003 ◽  
Author(s):  
I. Roumeliotis ◽  
N. Aretakis ◽  
K. Mathioudakis
Keyword(s):  
Gas Turbines ◽  
Water Injection ◽  
Diagnostic Procedures ◽  
Performance Model ◽  
Adaptive Performance ◽  
Diagnostic Ability ◽  
Modes Of Operation ◽  
Adaptive Models ◽  
Overall Performance ◽  
Selection Of

The development of an adaptive performance model for multi-spool gas turbines, equipped with the possibility of water injection is described. The model covers water injection at engine inlet, between the compressors and at the compressor exit. The selection of modification factors and the procedure for adapting component characteristics to overall performance data is discussed. A case of adaptation to overall performances is presented. The use of the model for studying overall engine and components performance is demonstrated. It is shown how operation with water injection modifies component operation, a fact that allows the identification of a wider range of the performance characteristics, in comparison to dry operation. This fact may also increase the diagnostic ability of techniques employing adaptive models. The sensitivity of diagnostic procedures to the different modes of operation of a gas turbine of the type described in the paper is also discussed.

scholarly journals Changes in the Perceived Epidemiology of Primary Hyperaldosteronism

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Riccardo Maria Fagugli ◽  
Chiara Taglioni
Keyword(s):  
Rare Disease ◽  
Resistant Hypertension ◽  
Primary Aldosteronism ◽  
Adult Population ◽  
Diagnostic Procedures ◽  
Pressure Control ◽  
Epidemiological Studies ◽  
High Incidence ◽  
Selection Of

Primary aldosteronism has been considered a rare disease in the past years, affecting 1% of the hypertensive population. Subsequently, growing evidence of its higher prevalence is present in literature, although the estimates of disease range from 5 up to 20%, as in type 2 diabetes and resistant hypertension. The main reasons for these variations are associated with the selection of patients and diagnostic procedures. If we consider that hypertension is present in about 20% of the adult population, primary aldosteronism can no longer be considered a rare disease. Patients with primary aldosteronism have a high incidence of cardiovascular, cerebrovascular and kidney complications. The identification of these patients has therefore a practical value on therapy, and to control morbidities derived from vascular damage. The ability to identify the prevalence of a disease depends on the number of subjects studied and the methods of investigation. Epidemiological studies are affected by these two problems: there is not consensus on patients who need to be investigated, although testing is recommended in subjects with resistant hypertension and diabetes. The question of how to determine aldosterone and renin levels is open, particularly if pharmacological wash-out is difficult to perform because of inadequate blood pressure control.

Referral Criteria for Selection of Patients and Diagnostic Procedures

1995 ◽  
Vol 57 (1-4) ◽  
pp. 3-8
Author(s):  
L. Dalla Palma ◽  
C. Ricci ◽  
S. Magnaldi (INVITED)
Keyword(s):  
Diagnostic Procedures ◽  
Referral Criteria ◽  
Selection Of Patients ◽  
Criteria For Selection ◽  
Selection Of

scholarly journals Development of Criteria for Epilepsy Genetic Testing in Ontario, Canada

2018 ◽  
Vol 46 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Puneet Jain ◽  
Danielle Andrade ◽  
Elizabeth Donner ◽  
David Dyment ◽  
Asuri N. Prasad ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Clinical Utility ◽  
Molecular Genetic ◽  
Public Funding ◽  
Diagnostic Procedures ◽  
Optimal Test ◽  
Genetic Tests ◽  
Gene Panels ◽  
General Guidance ◽  
Selection Of

AbstractMultiple genes/variants have been implicated in various epileptic conditions. However, there is little general guidance available on the circumstances in which genetic testing is indicated and test selection in order to guide optimal test appropriateness and benefit. This is an account of the development of guidelines for genetic testing in epilepsy, which have been developed in Ontario, Canada. The Genetic Testing Advisory Committee was established in Ontario to review the clinical utility and validity of genetic tests and the provision of genetic testing in Ontario. As part of their mandate, the committee also developed recommendations and guidelines for genetic testing in epilepsy. The recommendations include mandatory prerequisites for an epileptology/geneticist/clinical biochemical geneticist consultation, prerequisite diagnostic procedures, circumstances in which genetic testing is indicated and not indicated and guidance for selection of genetic tests, including their general limitations and considerations. These guidelines represent a step toward the development of evidence-based gene panels for epilepsy in Ontario, the repatriation of genetic testing for epilepsy into Ontario molecular genetic laboratories and public funding of genetic tests for epilepsy in Ontario.

Identifying Children with Learning Disabilities: A Comparison of Diagnostic Procedures across School Districts

1983 ◽  
Vol 6 (3) ◽  
pp. 321-328 ◽  
Author(s):  
Barry F. Perlmutter ◽  
Mildred V. Parus
Keyword(s):  
Learning Disabilities ◽  
School Districts ◽  
School Personnel ◽  
Diagnostic Procedures ◽  
Learning Disabled ◽  
Individual Interviews ◽  
Assessment Of Learning ◽  
Cutoff Scores ◽  
Testing Instruments ◽  
Selection Of

Diagnostic procedures used to identify children (grades K-6) with learning disabilities in 14 school districts were studied and compared. The degree of uniformity in procedures for initial referral, testing, and diagnostic criteria, as well as differences in the selection of testing instruments by various districts were examined. Information was gathered through individual interviews with school personnel involved in the assessment of learning disabled children within each district. Although some similarities existed between districts, uniformity was lacking in important areas such as test selection, extent of testing, and cutoff scores on intelligence and other tests. These findings are discussed in terms of their implications for the reliability of diagnoses across districts, as well as their meaning for researchers in the field.

scholarly journals Azocasein Substrate for Determination of Proteolytic Activity: Reexamining a Traditional Method Using Bromelain Samples

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Diego F. Coêlho ◽  
Thais Peron Saturnino ◽  
Fernanda Freitas Fernandes ◽  
Priscila Gava Mazzola ◽  
Edgar Silveira ◽  
...  
Keyword(s):  
Quality Control ◽  
Traditional Method ◽  
Reliable Method ◽  
Limit Of Detection ◽  
Standard Protocol ◽  
Mathematical Approach ◽  
Optimum Conditions ◽  
Limit Of Quantification ◽  
Selection Of

Given the importance of protease’s worldwide market, the determination of optimum conditions and the development of a standard protocol are critical during selection of a reliable method to determine its bioactivity. This paper uses quality control theory to validate a modified version of a method proposed by Charney and Tomarelli in 1947. The results obtained showed that using azocasein substrate bromelain had its optimum at 45°C and pH 9 (Glycine-NaOH 100 mM). We also quantified the limit of detection (LoD) and limit of quantification (LoQ) in the above-mentioned optimum (0.072 and 0.494 mg·mL−1of azocasein, resp.) and a calibration curve that correlates optical density with the amount of substrate digested. In all analysed samples, we observed a significant decrease in response after storage (around 17%), which suggests its use must be immediately after preparation. Thus, the protocol presented in this paper offers a significant improvement, given that subjective definitions are commonly used in the literature and this simple mathematical approach makes it clear and concise.

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