scholarly journals Granulocyte/Macrophage Colony-Forming Units from Cord Blood of Premature and Full-Term Neonates: Its Role in Ontogeny of Human Hemopoiesis

1988 ◽  
Vol 24 (6) ◽  
pp. 701-702 ◽  
Author(s):  
Der-Cherng Liang ◽  
Sheau-Wen Ma ◽  
Marie Lin-Chu ◽  
Chung-Chi Lan
Keyword(s):  
Cord Blood ◽  
Full Term ◽  
Term Neonates ◽  
Colony Forming Units ◽  
Macrophage Colony

High levels of granulocyte and granulocyte-macrophage colony-stimulating factors in cord blood of normal full-term neonates

1990 ◽  
Vol 116 (4) ◽  
pp. 627-632 ◽  
Author(s):  
Joseph Laver ◽  
Eva Duncan ◽  
Miguel Abboud ◽  
Cristina Gasparetto ◽  
Indira Sahdev ◽  
...  
Keyword(s):  
Cord Blood ◽  
Full Term ◽  
Term Neonates ◽  
Colony Stimulating Factors ◽  
Macrophage Colony

Cord Blood Alkaline Phosphatase as a predictor of Neonatal Jaundice in full term neonates

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Samah Esmail ◽  
Ali Abdo ◽  
Sherief Elgebaly ◽  
Marwa Mostafa
Keyword(s):  
Alkaline Phosphatase ◽  
Cord Blood ◽  
Neonatal Jaundice ◽  
Full Term ◽  
Term Neonates

scholarly journals Cord blood S100B: reference ranges and interest for early identification of newborns with brain injury

2020 ◽  
Vol 58 (2) ◽  
pp. 285-293 ◽  
Author(s):  
Damien Bouvier ◽  
Yves Giguère ◽  
Bruno Pereira ◽  
Nathalie Bernard ◽  
Isabelle Marc ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Brain Injury ◽  
Blood Serum ◽  
Cord Blood ◽  
Neurological Complications ◽  
Full Term ◽  
S100b Protein ◽  
Term Neonates ◽  
Cord Blood Serum

AbstractBackgroundNeurological complications are common in the premature and full-term neonates admitted to the intensive care unit, but the diagnosis of these complications is often difficult to make. S100B protein, measured in cord blood, may represent a valuable tool to better identify patients at risk of brain injury.MethodsAs a first step, we established S100B cord blood serum reference intervals from 183 preterm and 200 full-term neonates. We then measured cord blood serum S100B to identify neurological complications in 272 neonates hospitalized at the neonatal intensive care unit (NICU). Diagnosis of brain injury relied on imaging examination.ResultsThe 95th percentiles of S100B concentration in cord blood were established as 1.21 μg/L for the 383 neonates, 0.96 μg/L for full-term neonates and 1.36 μg/L for premature neonates. Among the 272 neonates hospitalized at the NICU, 11 presented neurological complications. Using 1.27 μg/L as the optimal sensitivity/specificity threshold, S100B differentiate neonates with and without neurological complications with a sensitivity of 45.5% (95% confidence intervals [CI]: 16.7–76.6) and a specificity of 88.9% (95% CI: 84.4–92.4) (p = 0.006). In combination with arterial pH (<7.25), sensitivity increased to 90.9% (95% CI: 58.7–99.8), while specificity was 51.2% (95% CI: 44.8–57.7). The sensitivity is significantly (p = 0.03) increased in comparison to S100B alone. The specificity is significantly higher with S100B only than with pH + S100B (p < 0.001).ConclusionsCord blood S100B protein, in combination with arterial cord blood pH, has the potential to help clinicians to detect at birth neurological complications in neonates hospitalized in an NCIU.

Clot formation of neonates tested by thromboelastography correlates with gestational age

2010 ◽  
Vol 103 (02) ◽  
pp. 344-350 ◽  
Author(s):  
Tzipi Strauss ◽  
Yael Levy-Shraga ◽  
Bruria Ravid ◽  
Irit Schushan-Eisen ◽  
Ayala Maayan-Metzger ◽  
...  
Keyword(s):  
Cord Blood ◽  
Gestational Age ◽  
Blood Clot ◽  
Full Term ◽  
Clot Formation ◽  
Clotting Time ◽  
Term Infants ◽  
Term Neonates ◽  
Pregnancy And Delivery ◽  
Clot Formation Time

SummaryEvaluation of clot formation in neonates is troublesome. Our aim was to investigate cord blood clot formation of pre-term versus full-term infants and adults, using rotating thromboelastogram (ROTEM®, Pentafarm, Munich, Germany). ROTEM was investigated in cord blood of 184 full-term and 47 pre-term infants. Measurements of the clotting time (CT), clot formation time (CFT) and maximal clot firmness (MCF) were obtained in order to asses reference values for this age group, and compare between full-term and pre-term neonates and compared to adult controls. For each infant demographic information and data regarding pregnancy and delivery were gathered. Infants were prospectively followed until discharge. CT and CFT were significantly shorter among pre-term and term infants as compared to adults [median CT: 185, 194, 293 seconds respectively, p≤0.001, CFT: 80, 76, 103 seconds respectively, p≤0.001). MCF was lower in pre-term and term as compared to adults (p≤0.001) with significantly lower values in pre-term as compared to full-term neonates (p=0.004). Clotting time and MCF correlated with gestational age (R=0.132, p=0.045, R= 0.259, p<0.001, respectively). No association was found between any ROTEM values and the occurrence of post-natal complications in infants of our study group. This is the first study assessing clot formation by ROTEM in pre-term infants. Clot formation parameters of term and premature infants correlated with gestational age. The predictive value of clot formation tests in neonates deserves further attention.

Umbilical cord blood CD45+/CD34+cells coexpression in preterm and full-term neonates: a pilot study

2010 ◽  
Vol 24 (2) ◽  
pp. 229-233 ◽  
Author(s):  
Sahar M. A. Hassanein ◽  
Hanaa A. Amer ◽  
Abeer A. Shehab ◽  
Mahmoud M. K. H. Hellal
Keyword(s):  
Pilot Study ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Full Term ◽  
Term Neonates ◽  
Cd34 Cells

scholarly journals Lipid profiles of umbilical cord blood: A comparative study in pre-term and full-term Newborns

2020 ◽  
Vol 11 (4) ◽  
pp. 7630-7633
Author(s):  
Om Prakash ◽  
Pradeep Kumar ◽  
Bhumija Sharma ◽  
Seema Goal ◽  
Preeti Sharma ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Cord Blood ◽  
Lipid Profile ◽  
Lipid Profiles ◽  
Full Term ◽  
Atherogenic Index ◽  
College Hospital ◽  
Term Neonates ◽  
Medical College ◽  
Future Risk

The foremost causes of death in developed and developing countries both are cardiovascular disorders. Higher concentration of lipids in pre term neonates may increase their future risk of cardiovascular diseases. Early diagnosis and dietary modifications and proper management may rectify the risk factors and prevent future risk of cardiovascular disease. Our study aims to compare lipid profiles and atherogenic index in the cord blood of pre-term and full-term neonates. It is a retrospective and observational study conducted for a period of one year from December 2018 to November 2019 in the Departments of Biochemistry and Gynecology of Santosh Medical College and Hospitals, Ghaziabad and K D Medical College Hospital and Research center. Among 60 neonates including 30 (50%) term and 30 (50%) preterm, TC, TG, LDL, VLDL, were raised in preterm when compared to term babies while HDL level was significantly increased (<0.05) in a term as compared to preterm babies. This study supports inverse relation between gestational age and lipid profile and this deranged lipid profile preterm group could be a threat or among factors for the future development of Atherosclerotic and cardiovascular diseases in their former part of life.

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