scholarly journals High Frequency Oscillatory Ventilation (HFOV) compared with High Rate Intermittent Positive Pressure Ventilation (IPPV) as First Line Therapy for Premature Infants with Respiratory Insufficiency. A Prospective Randomized Multicenter Trial † 1759

1998 ◽  
Vol 43 ◽  
pp. 300-300 ◽  
Author(s):  
U Thome ◽  
H Kössel ◽  
G Lipowsky ◽  
F Porz ◽  
H Fürste ◽  
...  
Author(s):  
Grenville Fox ◽  
Nicholas Hoque ◽  
Timothy Watts

This chapter includes sections on various modes of both invasive (i.e. via an endotracheal tube) and non-invasive respiratory support in neonates, including conventional ventilation, volume-targeted ventilation, high-frequency oscillatory ventilation (HFOV), extracorporeal membrane oxygenation (ECMO), nasal continuous positive airways pressure (nCPAP), nasal intermittent positive pressure ventilation (nIPPV), and high and low-flow nasal cannula oxygen. There is also a brief section on the care of babies with a tracheostomy as well as management of babies requiring home oxygen. Reference is made to the most recent European Consensus Guidelines. A separate chapter on neonatal respiratory problems (Chapter 7) gives further detail on common lung pathologies requiring respiratory support in neonates.


2019 ◽  
pp. 28-32
Author(s):  
Van Huy Tran

Background and aims: Efficacy with substitution of tetracycline with amoxicillin, an antibiotics having a very low resistance rate and a high tolerability, in bismuth quadruple therapy (BQT) have not been studied in Vietnam. Our study aimed to evaluate the efficacy and tolerability of modified BQT vs. standard BQT for first-line Helicobacter pylori eradication. Patients and methods: This is a randomized, prospective study. 120 patients with H.pylori positive-chronic gastritis were randomly divided into two groups. The RBMA group containing rabeprazole 20 mg, bismuth subsalicylic 524mg, metronidazole 500mg, amoxicillin 1000mg, all 2 times a day, for 14 days. The RBMT group received rabeprazole, bismuth subsalicylic, metronidazole and tetracycline. Evaluation for compliance and drug-related side effects were evaluated at the end of two weeks. 4-6 weeks after the end of treatment, the H.pylori eradication rate was determined by the C13urease breath test. Results: Eradication rate was not statistically significative different between the RBMA and the RBMT: 91.2%; 95% confidence interval, 78.2% - 96.7%) vs. 90%; 95% CI, 81.6% - 96.3%) by per-protocol analysis (p = 0.42) and 86.7% (95%CI, 75.84% - 93.09%) vs. 75% (95%CI, 62.1% - 85.3%) by intention-to-treat analysis (ITT, p = 0.06). Adverse effects were significant higher in the RBMT group than in the RBMA group (48.3% vs. 26.7%; p = 0.071) and rate of good compliance was significantly higher in RBMA group than in RBMT group (p < 0.05). Conclusion: The modified BQT including rabeprazole, bismuth, metronidazole and amoxicillin achieved a fairly high rate of H.pylori infection eradication with a higher compliance and lower rate of adverse effects compared to the BQT in patients with chronic gastritis. Further studies need to conduct to confirm this new regimens as a first-line therapy in our country. Key words: Modified bismuth quadruple therapy, BQT, Helicobacter pylori eradication


2021 ◽  
Vol 18 (3) ◽  
pp. 83-90
Author(s):  
Valentin-Caius Coșei

Abstract Obesity-hypoventilation syndrome (OHS) is the most severe complication of obesity, being burdened by numerous cardiovascular complications and an increase in the mortality rate. Late recognition of this syndrome is common. Approaching the patient with suspicion or confirmed with OHS requires a multidisciplinary team. Positive pressure treatment remains the first line therapy, with the highest efficiency. Weight loss should be recommended in all patients. Apparently, bariatric surgery is superior to lifestyle changes. Early detection and prompt treatment are of paramount importance to minimize adverse effects, which has necessitated consideration of this article.


PEDIATRICS ◽  
1987 ◽  
Vol 79 (1) ◽  
pp. 162-164
Author(s):  
THOMAS E. WISWELL ◽  
REESE H. CLARK ◽  
J. DEVN CORNISH

To the Editor.— We read with interest the study of Mammel et al.1 However, we wish to address several aspects of the report regarding the design of the investigation, their interpretation of the results and of other reports, and the conclusions they make. First, we take exception to the title itself. Unfortunately, many pediatricians and neonatologists do not make any distinction between the various types of nonconventional, high-frequency ventilators. High-frequency ventilation is a generic term encompassing several very different modalities of ventilation including high-frequency positive pressure ventilation, high-frequency flow interruption, high-frequency jet ventilation, and high-frequency oscillatory ventilation.


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