THE ROLE OF ENDOGENOUS OPIATES ON LH SECRETION DURING THE MENSTRUAL CYCLE

1980 ◽  
Vol 51 (1) ◽  
pp. 179-181 ◽  
Author(s):  
M.E. Quigley ◽  
S.S.C. Yen
2019 ◽  
Vol 1 (1) ◽  
pp. 53-60
Author(s):  
Rizky Aprilia Wikayanti ◽  
Andre Parmonangan Panjaitan

Kedelai merupakan tanaman Leguminoceae, yang mengandung senyawa isoflavon. Struktur kimianya menyerupai 17β-estradiol yang memiliki kemampuan untuk berikatan dengan reseptor estrogen yang dapat berpengaruh terhadap sistem reproduksi manusia. Tujuan literatur review ini untuk mengetahui efek kedelai terhadap sistem reproduksi manusia. Metode yang digunakan adalah metode literatur review dari 50 artikel PubMed NCBI, Elsevier dan BMJ Journal yang diperoleh hanya 38 artikel yang digumakan dari tahun 2000 sampai dengan tahun 2018. Berbagai penelitian eksperimental yang dilakukan menunjukkan bahwa kedelai memiliki efek terhadap sistem reproduksi manusia. Kedelai dapat menyebabkan sekresi FSH, sekresi LH menurun dan meningkatkan konsentrasi estradiol bebas. Penurunan FSH dan LH dapat menyebabkan gangguan dalam siklus menstruasi terutama pada fase folikular dan  ovulasi, jika fase folikular terganggu maka siklus menstruasi akan menjadi  tidak teratur. Selain itu fitoestrogen yang terkandung dalam kedelai diketahui dapat menghambat 17-β hidroksisteroidoksidoreduktase sehingga mengakibatkan penurunan kadar testosteron.   Kata kunci: kedelai, manusia, reproduksi   THE ROLE OF SOYBEAN FOR REPRODUCTIVE SYSTEM   ABSTRACT Soybean is a Leguminoceae plant, which contains isoflavone compounds. Its chemical structure resembles 17β-estradiol which has ability to bind to estrogen receptors which can affect the human reproductive system. The purpose of this review literature is to determine the effect of soy on the human reproductive system. Using research articles and books related to the effect of soy on the reproductive system from 2000 to 2018. Various experimental studies conducted showed that soy has an effect on the human reproductive system. Soy can cause FSH secretion, decreased LH secretion and increasing the free concentration of estradiol. Decreased FSH and LH can cause disruption in the menstrual cycle, especially in the follicular phase and ovulation, if the follicular phase is disrupted then the menstrual cycle will become irregular. In addition, phytoestrogens contained in soy are known to inhibit 17-β hydroxysteroidoxidoreductase, resulting in a decrease in testosterone levels.   Keywords : human, reproductive, soybean


Author(s):  
Abraham P. Buunk ◽  
Karlijn Massar ◽  
Pieternel Dijkstra ◽  
Ana María Fernández

This chapter discusses sex differences in intersexual competition and describes particularly the consequences of such competition for conflict between the sexes, as well as for sex differences in mate guarding and, relatedly, in the types of infidelity that evoke jealousy, including online infidelity. It also discusses individual differences in jealousy as related to attachment styles and describes the effects of height, hormones, and the menstrual cycle on jealousy. Next, the chapter moves on to intrasexual competition and discusses, among other topics, intrasexual competition among men and among women, the role of sex differences in rival characteristics in evoking jealousy, the role of attachment styles and hormones, and individual differences in intrasexual competitiveness.


2009 ◽  
Vol 106 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Marie K. Hoeger Bement ◽  
Rebecca L. Rasiarmos ◽  
John M. DiCapo ◽  
Audrey Lewis ◽  
Manda L. Keller ◽  
...  

2002 ◽  
Vol 173 (1) ◽  
pp. 113-122 ◽  
Author(s):  
AI Turner ◽  
BJ Canny ◽  
RJ Hobbs ◽  
JD Bond ◽  
IJ Clarke ◽  
...  

There are sex differences in the response to stress and in the influence of stress on reproduction which may be due to gonadal steroids but the nature of these differences and the role of the gonads are not understood. We tested the hypotheses that sex and the presence/absence of gonads (gonadal status) will influence the cortisol response to injection of ACTH, insulin-induced hypoglycaemia and isolation/restraint stress, and that sex and gonadal status will influence the secretion of LH in response to isolation/restraint stress. Four groups of sheep were used in each of three experiments: gonad-intact rams, gonadectomised rams, gonad-intact ewes in the mid-luteal phase of the oestrous cycle and gonadectomised ewes. In Experiment 1 (n=4/group), jugular blood samples were collected every 10 min for 6 h; after 3 h, two animals in each group were injected (i.v.) with ACTH and the remaining two animals were injected (i.v.) with saline. Treatments were reversed 5 days later so that every animal received both treatments. Experiment 2 (n=4/group) used a similar schedule except that insulin was injected (i.v.) instead of ACTH. In Experiment 3 (n=5/group), blood samples were collected every 10 min for 16 h on a control day and again 2 weeks later when, after 8 h of sampling, all sheep were isolated and restrained for 8 h. Plasma cortisol was significantly (P<0.05) elevated following injection of ACTH or insulin and during isolation/restraint stress. There were no significant differences between the sexes in the cortisol response to ACTH. Rams had a greater (P<0.05) cortisol response to insulin-induced hypoglycaemia than ewes while ewes had a greater (P<0.05) cortisol response to isolation/restraint stress than rams. There was no effect of gonadal status on these parameters. Plasma LH was suppressed (P<0.05) in gonadectomised animals during isolation/restraint stress but was not affected in gonad-intact animals, and there were no differences between the sexes. Our results show that the sex that has the greater cortisol response to a stressor depends on the stressor imposed and that these sex differences are likely to be at the level of the hypothalamo-pituitary unit rather than at the adrenal gland. Since there was a sex difference in the cortisol response to isolation/restraint, the lack of a sex difference in the response of LH to this stress suggests that glucocorticoids are unlikely to be a major mediator of the stress-induced suppression of LH secretion.


1993 ◽  
Vol 23 (1) ◽  
pp. 1-27 ◽  
Author(s):  
Uriel Halbreich ◽  
Henry Tworek

Objective: Dysphoric Premenstrual Syndromes (PMS) are quite prevalent and in some women they are severe enough to warrant treatment. Their pathophysiology is still unknown, despite increased interest and research. Here we review the possible role of serotonin in the multidimensional interactive pathophysiology of PMS. Method: Over 170 articles are reviewed. An extensive library search has been conducted and articles are included because of their relevance to: 1) the phenomenology of PMS; 2) the putative association of serotonergic (5-HT) activity with syndromes that occur premenstrually; 3) changes in 5-HT activity along the menstrual cycle, especially the late luteal phase; 4) influence of gonadal hormones on serotonergic functions; 5) endocrine strategies for assessment of 5-HT abnormalities; and 6) treatment studies of PMS with serotonergic agonists. Results and Conclusions: The data presented here suggest that post-synaptic serotonergic responsivity might be altered during the late-luteal-premenstrual phase of the menstrual cycle. Some serotonergic functions of women with PMS might be altered during the entire cycle and be associated with a vulnerability trait. It is hypothesized that gonadal hormones might cause changes in levels of activity of 5-HT systems as part of a multidimensional interactive system. Strategies to evaluate 5-HT activities in the context of the menstrual cycle are discussed—leading to the conclusion that the most promising approach is active stimulation with specific post-synaptic serotonin agonists. Treatment outcome studies of some imperfect compounds that are currently applied as a symptomatic treatment of PMS support the notion that 5-HT is involved in the pathophysiology of these syndromes.


BMJ ◽  
1985 ◽  
Vol 290 (6470) ◽  
pp. 739-740 ◽  
Author(s):  
K De Meirleir ◽  
T Arentz ◽  
W Hollmann ◽  
L Vanhaelst

1994 ◽  
Vol 8 (3) ◽  
pp. 151-159 ◽  
Author(s):  
W. G. Rossmanith ◽  
B. Schenkel ◽  
R. Benz

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