Insulinoma and Tuberous Sclerosis: A Possible Mechanistic Target of Rapamycin (mTOR) Pathway Abnormality?

Journal of the Endocrine Society ◽

10.1210/js.2017-00160 ◽

2017 ◽

Vol 1 (9) ◽

pp. 1120-1123

Author(s):

Michael Yoon Kang ◽

Joey Yeoh ◽

Ashwini Pondicherry ◽

Habib Rahman ◽

Ajith Dissanayake

Keyword(s):

Tuberous Sclerosis ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy

Autophagy ◽

10.4161/auto.22791 ◽

2013 ◽

Vol 9 (2) ◽

pp. 175-195 ◽

Author(s):

He Huang ◽

Rongyan Kang ◽

Ji Wang ◽

Guangxiang Luo ◽

Wei Yang ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Endoplasmic Reticulum Stress ◽

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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Inhibition of the mechanistic target of rapamycin induces cell survival via MAPK in tuberous sclerosis complex

Orphanet Journal of Rare Diseases ◽

10.1186/s13023-020-01490-w ◽

2020 ◽

Vol 15 (1) ◽

Author(s):

Yiyang Lu ◽

Erik Y. Zhang ◽

Jie Liu ◽

Jane J. Yu

Keyword(s):

Cell Survival ◽

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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The mechanistic target of rapamycin (mTOR) pathway and S6 Kinase mediate diazoxide preconditioning in primary rat cortical neurons

Journal of Neurochemistry ◽

10.1111/jnc.13181 ◽

2015 ◽

Vol 134 (5) ◽

pp. 845-856 ◽

Author(s):

Somhrita Dutta ◽

Ibolya Rutkai ◽

Prasad V. G. Katakam ◽

David W. Busija

Keyword(s):

Cortical Neurons ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

S6 Kinase ◽

Mechanistic Target Of Rapamycin ◽

Rat Cortical Neurons

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Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy

Neuropathology and Applied Neurobiology ◽

10.1111/nan.12463 ◽

2018 ◽

Vol 44 (1) ◽

pp. 6-17 ◽

Author(s):

E. Marsan ◽

S. Baulac

Keyword(s):

Focal Cortical Dysplasia ◽

Cortical Dysplasia ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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Tuberous Sclerosis Complex 1–Mechanistic Target of Rapamycin Complex 1 Signaling Determines Brown-to-White Adipocyte Phenotypic Switch

Diabetes ◽

10.2337/db14-0427 ◽

2014 ◽

Vol 64 (2) ◽

pp. 519-528 ◽

Author(s):

Xinxin Xiang ◽

He Lan ◽

Hong Tang ◽

Fang Yuan ◽

Yanhui Xu ◽

...

Keyword(s):

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Target Of Rapamycin ◽

Phenotypic Switch ◽

White Adipocyte ◽

Mechanistic Target Of Rapamycin

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Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex

Neurobiology of Disease ◽

10.1016/j.nbd.2019.104615 ◽

2020 ◽

Vol 134 ◽

pp. 104615 ◽

Author(s):

Bo Zhang ◽

Dongjun Guo ◽

Lirong Han ◽

Nicholas Rensing ◽

Akiko Satoh ◽

...

Keyword(s):

Mouse Model ◽

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Target Of Rapamycin ◽

Sleep Dysfunction ◽

Mechanistic Target Of Rapamycin

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Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome

The Journal of Physiology ◽

10.1113/jphysiol.2013.256339 ◽

2013 ◽

Vol 591 (18) ◽

pp. 4611-4620 ◽

Author(s):

Brittany L. Jacobs ◽

Jae-Sung You ◽

John W. Frey ◽

Craig A. Goodman ◽

David M. Gundermann ◽

...

Keyword(s):

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Target Of Rapamycin ◽

Eccentric Contractions ◽

Mechanistic Target Of Rapamycin

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Dermatological adverse events associated with use of oral mechanistic target of rapamycin inhibitors in a cohort of individuals with tuberous sclerosis complex

British Journal of Dermatology ◽

10.1111/bjd.19124 ◽

2020 ◽

Vol 183 (3) ◽

pp. 588-589 ◽

Author(s):

D.J. Pithadia ◽

A.M. Treichel ◽

A.M. Jones ◽

P. Julien‐Williams ◽

T. Machado ◽

...

Keyword(s):

Adverse Events ◽

Tuberous Sclerosis ◽

Tuberous Sclerosis Complex ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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Mouse Oocytes Promote the Mechanistic Target of Rapamycin (Serine/Threonine Kinase, MTOR) Pathway in Cumulus Cells by Suppressing the Expression of DNA-damage-inducible Transcript 4-like (Ddit4l).

Biology of Reproduction ◽

10.1093/biolreprod/83.s1.149 ◽

2010 ◽

Vol 83 (Suppl_1) ◽

pp. 149-149

Author(s):

You-Qiang Su ◽

Koji Sugiura ◽

Karen Wigglesworth ◽

John J. Eppig

Keyword(s):

Cumulus Cells ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Serine Threonine Kinase ◽

Threonine Kinase ◽

Mechanistic Target Of Rapamycin ◽

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Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2018.03.008 ◽

2018 ◽

Vol 836 ◽

pp. 103-113 ◽

Author(s):

Kalpana Gopalakrishnan ◽

Shriram Venkatesan ◽

Esther Su Hui Low ◽

M. Prakash Hande

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Mtor Pathway ◽

Target Of Rapamycin ◽

Mechanistic Target Of Rapamycin

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