Author response: ALS-specific cognitive and behavior changes associated with advancing disease stage in ALS

Obesity is one of the biggest health problems globally that, together with sedentarism, requires solutions that increase the enthusiasm towards physical activity. Therefore, this paper describes two solutions based on active games using the Kinect sensor and biometric sensors, designed for the outpatient treatment of childhood obesity. The solutions were applied in an intervention program based on active video games and motor games, developed with children in treatment for childhood obesity. An ad hoc questionnaire was used to assess the level of satisfaction, fun, learning, and behavior changes in the children of the experimental group that developed the intervention. The results showed a high index of satisfaction with the intervention program, as well as with the games developed. It is concluded that active video games and group games are highly motivating and can promote behavior change towards healthier life habits in children.

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[IC-P-046]: DIABETES-ASSOCIATED AMYLIN DYSHOMEOSTASIS PROVOKES BRAIN WHITE MATTER DISEASE AND BEHAVIOR CHANGES: AN ANIMAL MODEL

Alzheimer s & Dementia ◽

10.1016/j.jalz.2017.06.2318 ◽

2017 ◽

Vol 13 (7S_Part_1) ◽

pp. P39-P40

Author(s):

Han Ly ◽

Nirmal Verma ◽

Miao Liu ◽

Fengen Wu ◽

Florin Despa

Keyword(s):

Animal Model ◽

White Matter ◽

Behavior Changes ◽

White Matter Disease ◽

Brain White Matter ◽

And Behavior

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PARENTAL REPORTS OF SEASONAL MOOD AND BEHAVIOR CHANGES IN CHILDREN

PEDIATRICS ◽

10.1542/peds.94.5.a70 ◽

1994 ◽

Vol 94 (5) ◽

pp. A70-A70

Author(s):

Mary A. Carskadon ◽

Christine Acebo

Keyword(s):

Response Rate ◽

Light Therapy ◽

The United States ◽

Therapeutic Benefit ◽

Behavior Changes ◽

Regional Effects ◽

Parental Reports ◽

And Behavior ◽

Potential Therapeutic Benefit ◽

Careful Assessment

Objective: The chief purpose of this study was to investigate the nature and prevalence of children's seasonal symptoms. Method: Parental reports of seasonal changes in six mood or behavioral symptoms (sleeping, eating, irritability, energy, withdrawal, and sadness) were surveyed for children living across the United States. The sample included 892 girls (mean age = 10.5 ± 1.0 years) and 788 boys (mean age = 10.6 ± 0.9 years), with a response rate of 46% for girls' parents and 39% for boys' parents. Results: At least one winter recurring symptom was reported in 48.5% of children, as compared with 91% in fall and 10.8% in spring. Winter symptoms were reported equally in girls and boys with one exception ("is tired"); age effects were found for three symptoms only in girls ("sleeps more," "is tired," and "withdraws"). Regional effects showed more winter symptoms reports in northern zones than in southern zones. Conclusions: Given the potential therapeutic benefit of light therapy in children with seasonal patterns, careful assessment of seasonality is merited for children with winter mood and behavior problems.

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The most problematic symptoms of prion disease – an analysis of carer experiences

International Psychogeriatrics ◽

10.1017/s1041610218001588 ◽

2018 ◽

Vol 31 (08) ◽

pp. 1181-1190

Author(s):

Liz Ford ◽

Peter Rudge ◽

Kathy Robinson ◽

John Collinge ◽

Michele Gorham ◽

...

Keyword(s):

Outcome Measures ◽

Prion Disease ◽

Prion Diseases ◽

Formal Analysis ◽

Structured Interview ◽

Disease Stage ◽

Structured Interviews ◽

Wide Range ◽

The Uk ◽

And Behavior

ABSTRACTObjectives:Prion diseases are rare dementias that most commonly occur sporadically, but can be inherited or acquired, and for which there is no cure. We sought to understand which prion disease symptoms are most problematic for carers, to inform the development of outcome measures.Design:Self-completed questionnaire with follow-up of a subset of participants by structured interview.Setting:A nested study in the UK National Prion Monitoring Cohort, a longitudinal observational study.Participants and measurements:71 carers, of people with different prion diseases with a wide range of disease severity, identified 236 of their four most problematic symptoms by questionnaire which were grouped into ten domains. Structured interviews were then done to qualitatively explore these experiences. Eleven family carers of people with prion disease were selected, including those representative of a range of demographics and disease subtypes and those who cared for people with prion disease, living or recently deceased. Interviews were transcribed and formally studied.Results:The six most problematic symptom domains were: mobility and coordination; mood and behavior; personal care and continence; eating and swallowing; communication; and cognition and memory. The prevalence of these symptoms varied significantly by disease stage and type. A formal analysis of structured interviews to explore these domains is reported.Conclusions:We make suggestions about how healthcare professionals can focus their support for people with prion disease. Clinical trials that aim to generate evidence regarding therapies that might confer meaningful benefits to carers should consider including outcome measures that monitor the symptomatic domains we have identified as problematic.

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Author response: Ubiquitin-dependent regulation of a conserved DMRT protein controls sexually dimorphic synaptic connectivity and behavior

10.7554/elife.59614.sa2 ◽

2020 ◽

Author(s):

Emily A Bayer ◽

Rebecca C Stecky ◽

Lauren Neal ◽

Phinikoula S Katsamba ◽

Goran Ahlsen ◽

...

Keyword(s):

Author Response ◽

Synaptic Connectivity ◽

Sexually Dimorphic ◽

And Behavior

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