scholarly journals Persistent postural perceptual dizziness is on a spectrum in the general population

Neurology ◽  
2020 ◽  
Vol 94 (18) ◽  
pp. e1929-e1938 ◽  
Author(s):  
Georgina Powell ◽  
Hannah Derry-Sumner ◽  
Deepak Rajenderkumar ◽  
Simon K. Rushton ◽  
Petroc Sumner
Keyword(s):  
General Population ◽  
Analogue Scale ◽  
The Other ◽  
Community Research ◽  
Situational Characteristics ◽  
Visual Vertigo ◽  
Research Volunteers

ObjectiveTo examine the idea that symptoms of persistent postural perceptual dizziness (PPPD) are more common than previously assumed and lie on a spectrum in the general population, thus challenging current theories that PPPD is only a consequence of a vestibular insult.MethodsWe collected 2 common clinical questionnaires of PPPD (Visual Vertigo Analogue Scale [VVAS] and Situational Characteristics Questionnaire [SCQ]) in 4 cohorts: community research volunteers (n = 1941 for VVAS, n = 1,474 for SCQ); paid online participants (n = 190 for VVAS, n = 125 for SCQ); students (n = 204, VVAS only); and patients diagnosed with PPPD (n = 25).ResultsWe found that around 9%, 4%, and 11%, respectively, of the 3 nonclinical cohorts scored above the 25th percentile patient score on 1 PPPD measure (VVAS) and 49% and 54% scored above the 25th percentile patient score on the other measure (SCQ). Scores correlated negatively with age (counter to expectation). As expected, scores correlated with migraine in 2 populations, but this only explained a small part of the variance, suggesting that migraine is not the major factor underlying the spectrum of PPPD symptoms in the general population.ConclusionWe found high levels of PPPD symptoms in nonclinical populations, suggesting that PPPD is a spectrum that preexists in the population, rather than only being a consequence of vestibular insult. Atypical visuo-vestibular processing predisposes some individuals to visually induced dizziness, which is then exacerbated should vestibular insult (or more generalized insult) occur.

Arterial stiffness could reflect increased cardiac load and reduced pulmonary function in the general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S Murai ◽  
T Sugiura ◽  
Y Dohi ◽  
H Takase ◽  
T Mizoguchi ◽  
...  
Keyword(s):  
Regression Analysis ◽  
General Population ◽  
Arterial Stiffness ◽  
Pulmonary Function ◽  
Multivariate Regression ◽  
Troponin I ◽  
Augmentation Index ◽  
Smoking Status ◽  
Multivariate Regression Analysis ◽  
The Other

Abstract Background Pulmonary function is known to decrease with age and reduced pulmonary function has been reported to be associated with all-cause mortality and cardiovascular death. The association between pulmonary impairment and atherosclerosis was reported previously but has not been investigated sufficiently in the general population. Purpose We hypothesized that arterial stiffness could reflect increase of cardiac load and reduced pulmonary function. The present study aimed to investigate whether increased cardiac load and reduced pulmonary function could affect arterial stiffness in the general population. Methods Subjects undergoing their health check-up were enrolled. Plasma B-type natriuretic peptide (BNP) levels and serum high-sensitivity cardiac troponin I (hs-cTnI) levels were measured to evaluate cardiac load and myocardial damage. Radial augmentation index (rAI) was measured to investigate arterial stiffness using HEM-9000AI device. Subjects with an ST-T segment abnormality on the electrocardiogram, renal insufficiency, cancer, active inflammatory disease, or a history of cardiovascular events and pulmonary disease were excluded. Pulmonary function was assessed using spirometry by calculating forced vital capacity (FVC) as a percentage of predicted value (FVC%-predicted), forced expiratory volume in 1 second (FEV1) as a percentage of predicted value (FEV1%-predicted), and the ratio of FEV1 to FVC (FEV1/FVC). Results A total of 1100 subjects aged 57 years were enrolled and their median values of BNP and hs-cTnI were 15.5 and 2.3 pg/ml. The levels of rAI were significantly associated with the levels of BNP after adjustment for possible confounders in multivariate regression analysis, but were not with the levels of hs-TnI. While the parameters of pulmonary function were inversely associated with the levels of rAI and hs-cTnI after adjustment for possible confounders in the multivariate regression analysis, but not with the levels of BNP. The other multivariate regression analyses where BNP, hs-cTnI, parameters of pulmonary function, and the other possible factors were simultaneously included as independent variables revealed that the BNP levels and the FVC%-predicted or FEV1%-predicted, besides age, gender, smoking status, body mass index, blood pressure, heart rate, creatinine, fasting plasma glucose, and triglyceride, were significantly associated with the levels of rAI. Conclusions The significant associations of rAI with BNP and pulmonary function were revealed in the general population. These findings support that arterial stiffness could reflect increased cardiac load and reduced pulmonary function, in apparently healthy individuals. Funding Acknowledgement Type of funding source: None

Preliminary Communication: 2: The Highlands Dependency Questionnaire (HDQ): An administered version for use with mothers of school children

1971 ◽  
Vol 1 (4) ◽  
pp. 343-347 ◽  
Author(s):  
Ian Berg ◽  
Ralph McGuire ◽  
Edward Whelan
Keyword(s):  
General Population ◽  
Secondary School ◽  
School Children ◽  
Reliability And Validity ◽  
Principal Component ◽  
The Other ◽  
Factor Analyses ◽  
Child Relationship ◽  
Preliminary Communication ◽  
Mother Child Relationship

SYNOPSISA questionnaire concerned with dependency, mainly in the mother–child relationship, and intended for use in child psychiatry, is described. It was administered to the mothers of 116 randomly selected junior and secondary school children in the general population, stratified into age, sex, social class, and school groupings. Two meaningful dimensions were revealed by principal component factor analyses: one concerned with reliance on mother and the other reflecting sociability. Reliability and validity were found to be satisfactory.

Traducción y adaptación transcultural del cuestionario Visual Vertigo Analogue Scale para uso en Argentina

2020 ◽  
Vol 71 (5) ◽  
pp. 289-295
Author(s):  
Daniel Héctor Verdecchia ◽  
Daniel Hernandez ◽  
Mauro Federico Andreu ◽  
Sandra Salzberg
Keyword(s):  
Analogue Scale ◽  
Visual Vertigo

Visual Vertigo Analogue Scale

2011 ◽  
Author(s):  
Elizabeth Dannenbaum ◽  
Gevorg Chilingaryan ◽  
Joyce Fung
Keyword(s):  
Analogue Scale ◽  
Visual Vertigo

scholarly journals Estimation of the Inhaled Dose of Airborne Pollutants during Commuting: Case Study and Application for the General Population

2020 ◽  
Vol 17 (17) ◽  
pp. 6066
Author(s):  
Francesca Borghi ◽  
Giacomo Fanti ◽  
Andrea Cattaneo ◽  
Davide Campagnolo ◽  
Sabrina Rovelli ◽  
...  
Keyword(s):  
General Population ◽  
Pulmonary Ventilation ◽  
Ventilation Rate ◽  
The Other ◽  
Winter Period ◽  
Airborne Pollutants ◽  
Traffic Conditions ◽  
High Concentrations ◽  
The City

During rush hours, commuters are exposed to high concentrations and peaks of traffic-related air pollutants. The aims of this study were therefore to extend the inhaled dose estimation outcomes from a previous work investigating the inhaled dose of a typical commuter in the city of Milan, Italy, and to extend these results to a wider population. The estimation of the dose of pollutants inhaled by commuters and deposited within the respiratory tract could be useful to help commuters in choosing the modes of transport with the lowest exposure and to increase their awareness regarding this topic. In addition, these results could provide useful information to policy makers, for the creation/improvement of a mobility that takes these results into account. The principal result outcomes from the first part of the project (case study on a typical commuter in the city of Milan) show that during the winter period, the maximum deposited mass values were estimated in the “Other” environments and in “Underground”. During the summer period, the maximum values were estimated in the “Other” and “Walking (high-traffic conditions)” environments. For both summer and winter, the lowest values were estimated in the “Car” and “Walking (low-traffic conditions)” environments. Regarding the second part of the study (the extension of the results to the general population of commuters in the city of Milan), the main results show that the period of permanence in a given micro-environment (ME) has an important influence on the inhaled dose, as well as the pulmonary ventilation rate. In addition to these results, it is of primary importance to report how the inhaled dose of pollutants can be strongly influenced by the time spent in a particular environment, as well as the subject’s pulmonary ventilation rate and pollutant exposure levels. For these reasons, the evaluation of these parameters (pulmonary ventilation rate and permanence time, in addition to the exposure concentration levels) for estimating the inhaled dose is of particular relevance.

scholarly journals Hepatitis C in Hemodialysis Units: diagnosis and therapeutic approach

2019 ◽  
Vol 41 (4) ◽  
pp. 539-549
Author(s):  
Natasha Silva Constancio ◽  
Maria Lucia Gomes Ferraz ◽  
Carmen Tzanno Branco Martins ◽  
Angiolina Campos Kraychete ◽  
Paulo Lisboa Bitencourt ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Population ◽  
Horizontal Transmission ◽  
Review Article ◽  
The Other ◽  
Disease Eradication ◽  
Brazilian Society ◽  
Near Future

Abstract According to data from the last census of the Brazilian Society of Nephrology (SBN), the prevalence of hepatitis C virus (HCV) in Brazilian hemodialysis units (HU) is 3.3%, about three times higher than what is reported for the Brazilian general population. Often, professionals working in HU are faced with clinical situations that require rapid HCV diagnosis in order to avoid horizontal transmission within the units. On the other hand, thanks to the development of new antiviral drugs, the cure of patients with HCV, both in the general population and in patients with chronic kidney disease and the disease eradication, appear to be very feasible objectives to be achieved in the near future . In this scenario, SBN and the Brazilian Society of Hepatology present in this review article a proposal to approach HCV within HUs.

Contribution to the Study of the Death-rate of Persons in Asylums

1879 ◽  
Vol 25 (109) ◽  
pp. 1-4
Author(s):  
Arthur Mitchell
Keyword(s):  
General Population ◽  
Death Rate ◽  
The Other ◽  
Other Hand ◽  
Different Ages ◽  
The Mean ◽  
General Community

In the population of Scotch Asylums, there are so few persons below the age of 10 years that, for practical purposes, it may be correctly said there are none. of the general community, on the other hand, 25·6 per cent. are persons below that age. It is clear, therefore, that the death-rate of the population of asylums cannot properly be compared with the death-rate of the general population. To make such a comparison it is necessary to deal only with the deaths occurring among the 74·4 per cent. of the general community who are above the age of 10 years. When this is done, it appears that the mean annual death-rate for the general population is 1·7 per cent. as compared with 8·3 per cent. for the population of asylums. These figures refer to the whole population of asylums, and to the whole of the general population above the age of 10 years; but in order to show the rates at which persons of different ages die in asylums, and the rates at which persons of corresponding ages die in the general community, the following table has been prepared. It is founded on 3,800 deaths occurring during the seven years, 1870–1876, in the Asylums of Scotland, which had a mean population of 6,421 during those years.

Memory Characteristics of College Students Who Volunteer for Research

1997 ◽  
Vol 80 (2) ◽  
pp. 515-520 ◽  
Author(s):  
David S. Kreiner ◽  
Matilda Alvarado ◽  
Shawna R. Shockley
Keyword(s):  
College Student ◽  
General Population ◽  
Verbal Memory ◽  
Visual Memory ◽  
Psychological Research ◽  
Wechsler Memory Scale ◽  
Memory And Attention ◽  
Student Volunteers ◽  
Research Volunteers ◽  
Memory Characteristics

Volunteers for psychological research can differ in important ways from nonvolunteers and from the general population. The memory abilities of a sample of 80 college student research volunteers were measured using the Wechsler Memory Scale–Revised. Compared to general population norms, the sample scored significantly higher on General Memory and Visual Memory compared to those with more than 12 years of education, the sample scored significantly lower on General Memory, Verbal Memory, and Attention but significantly higher on Visual Memory. Although results may vary at different universities, researchers should be cautious in assuming that the memory abilities of samples of college student volunteers accurately represent the population.

Documentation of Ethnicity

2004 ◽  
Vol 95 (3) ◽  
pp. 859-861 ◽  
Author(s):  
James Robert Brašić
Keyword(s):  
United States ◽  
General Population ◽  
Care Facility ◽  
The United States ◽  
Ethnic Composition ◽  
The Other ◽  
Intermediate Care ◽  
Minority Status ◽  
White Population ◽  
United States Census

The comparison of the ethnic composition of an intermediate care facility with several Hispanic residents and the general population was hindered by the absence of categorization of ethnicity according to the United States Census. If all Hispanic residents of the facility were white, then 55% of the facility population were white, a proportion comparable to the 58.2% white population of the general population. On the other hand, if all the Hispanic residents were not white, then 27.5% of the facility residents were white. In that case, the proportion of white residents of the facility is much less than in the general population. Therefore, a Demographic Coding Form was developed to capture the essential data to make direct comparisons and contrasts with the general population recorded by the United States Census. Since the United States Census records Hispanic ethnic minority status as a separate category independent from all other ethnic groups, the design of experiments to investigate the possible effects of ethnicity on populations wisely incorporates the administration of a Demographic Coding Form to capture the key ethnic data to permit direct comparison with the general population.

scholarly journals The significance of haemochromatosis gene mutations in the general population: implications for screening

Gut ◽  
1998 ◽  
Vol 43 (6) ◽  
pp. 830-836 ◽  
Author(s):  
M J Burt ◽  
P M George ◽  
J D Upton ◽  
J A Collett ◽  
C M A Frampton ◽  
...  
Keyword(s):  
General Population ◽  
Serum Iron ◽  
Deoxyribonucleic Acid ◽  
Iron Status ◽  
Transferrin Saturation ◽  
Gene Mutations ◽  
The Other ◽  
Phenotypic Screening ◽  
C282y Mutation ◽  
C282y Homozygosity

Background—Haemochromatosis is associated with mutations in the HFE gene but the significance of these mutations in the general population is unknown.Aims—To determine the frequency ofHFE gene mutations in the general population, their effect on serum iron indexes, and their role in screening for haemochromatosis.Methods—Deoxyribonucleic acid (DNA) from 1064 randomly selected subjects was analysed for the C282Y and H63D mutations in the HFE gene. Serum iron, transferrin saturation, and ferritin were measured and individuals with increased iron indexes were investigated to confirm or exclude a clinical diagnosis of haemochromatosis.Results—Mutations were identified in 409 individuals (38.4%) with heterozygote (carrier) frequencies of 13.2% and 24.3% for the C282Y and H63D mutations respectively. Heterozygosity for either mutation significantly increased serum iron and transferrin saturation but despite a similar trend for ferritin, this was only significant for C282Y homozygotes. Five individuals (0.47%) were homozygous for the C282Y mutation, three of whom had haemochromatosis confirmed by liver biopsy (0.28%). The other two C282Y homozygotes would not have been detected by phenotypic screening alone.Conclusions—HFE mutations are present in 38.4% of the population, affect serum iron indexes, and are important determinants of iron status. The population frequency of genetically defined haemochromatosis (C282Y homozygosity) is approximately one in 200 and is higher than the prevalence of clinically apparent haemochromatosis.

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