scholarly journals The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival

Development ◽  
2017 ◽  
Vol 145 (1) ◽  
pp. dev154468 ◽  
Author(s):  
Stefan Norlin ◽  
Vishal Parekh ◽  
Helena Edlund

2016 ◽  
Vol 5 (1) ◽  
pp. 278-290 ◽  
Author(s):  
M. Richter ◽  
E. A. Fairhall ◽  
S. A. Hoffmann ◽  
S. Tröbs ◽  
F. Knöspel ◽  
...  

The rat pancreatic progenitor cell line B-13 is of interest for research on drug metabolism and toxicity since the cells trans-differentiate into functional hepatocyte-like cells (B-13/H) when treated with glucocorticoids.







2003 ◽  
Vol 370 (3) ◽  
pp. 763-769 ◽  
Author(s):  
Carylyn J. MAREK ◽  
Gary A. CAMERON ◽  
Lucy J. ELRICK ◽  
Gabrielle M. HAWKSWORTH ◽  
Matthew C. WRIGHT

The proliferating AR42J-B13 pancreatic cell line is known to respond to glucocorticoid treatment by producing foci of cells that express the liver-specific albumin gene. We demonstrate that this cell line also expresses liver-specific or liver-enriched functional cytochrome P450 proteins when stimulated to trans-differentiate into hepatocytes by glucocorticoid. These data suggest that this cell line has an unusual ability to trans-differentiate into functional hepatocytes and that it could be possible to generate a limitless supply of functional hepatocyte-like cells in vitro.



2007 ◽  
Vol 104 (6) ◽  
pp. 1865-1870 ◽  
Author(s):  
P. A. Seymour ◽  
K. K. Freude ◽  
M. N. Tran ◽  
E. E. Mayes ◽  
J. Jensen ◽  
...  


Diabetes ◽  
2019 ◽  
Vol 68 (9) ◽  
pp. 1806-1818 ◽  
Author(s):  
Jason M. Spaeth ◽  
Jin-Hua Liu ◽  
Daniel Peters ◽  
Min Guo ◽  
Anna B. Osipovich ◽  
...  


2011 ◽  
pp. OR01-5-OR01-5
Author(s):  
Lauren Elizabeth Eastwood ◽  
Adam Stevens ◽  
Ruth Mary Shepherd ◽  
Ju Kim ◽  
Leo Zeef ◽  
...  


2006 ◽  
Vol 281 (19) ◽  
pp. 13574-13580 ◽  
Author(s):  
Hong Hua ◽  
You-Qing Zhang ◽  
Sandrine Dabernat ◽  
Marcie Kritzik ◽  
Daisy Dietz ◽  
...  


2015 ◽  
Vol 7 (21) ◽  
pp. 11624-11630 ◽  
Author(s):  
Jia Yang ◽  
Fang Zhou ◽  
Rubo Xing ◽  
Yuan Lin ◽  
Yanchun Han ◽  
...  


Diabetes ◽  
2016 ◽  
Vol 65 (5) ◽  
pp. 1297-1309 ◽  
Author(s):  
Jennifer E. Bruin ◽  
Nelly Saber ◽  
Shannon O’Dwyer ◽  
Jessica K. Fox ◽  
Majid Mojibian ◽  
...  


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