scholarly journals Science shines in a new virtual SY-Stem

Development ◽  
2021 ◽  
Vol 148 (12) ◽  
Author(s):  
Christa Buecker ◽  
Florian T. Merkle
Keyword(s):  
Stem Cell ◽  
Cell Biology ◽  
Young Group ◽  
Early Career ◽  
Stem Cell Biology ◽  
Group Leaders ◽  
Postgraduate Students ◽  
Early Career Researchers ◽  
Excellent Work ◽  
Species Specific

ABSTRACT The third ‘Symposium for the Next Generation of Stem Cell Research’ (SY-Stem) was held virtually on 3-5 March 2021, having been cancelled in 2020 due to the COVID-19 pandemic. As in previous years, the meeting highlighted the work of early career researchers, ranging from postgraduate students to young group leaders working in developmental and stem cell biology. Here, we summarize the excellent work presented at the Symposium, which covered topics ranging from pluripotency, species-specific aspects of development and emerging technologies, through to organoids, single-cell technology and clinical applications.

scholarly journals Future leader to watch – Aaron Savage

Biology Open ◽  
2021 ◽  
Vol 10 (10) ◽  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Regenerative Medicine ◽  
Cell Biology ◽  
Early Career ◽  
Stem Cell Biology ◽  
Early Career Researchers ◽  
Research Associate ◽  
Postdoctoral Research ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Aaron Savage is first author on ‘ Germline competent mesoderm: the substrate for vertebrate germline and somatic stem cells?’, published in BiO. Aaron is a postdoctoral research associate at the Biodiscovery Institute, University of Nottingham, United Kingdom, investigating how stem cells can be used in regenerative medicine and how we can understand stem cell biology using embryonic and post-embryonic development.

scholarly journals First person – Federico Pecori

2020 ◽  
Vol 133 (20) ◽  
pp. jcs255166
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Embryonic Stem Cells ◽  
Cell Biology ◽  
Embryonic Stem ◽  
Early Career ◽  
First Person ◽  
Receptor Endocytosis ◽  
Early Career Researchers ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Federico Pecori is first author on ‘Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis’, published in JCS. Federico is a PhD student in the lab of Shoko Nishihara at the Laboratory of Cell Biology, Department of Bioinformatics, Soka University, Tokyo, Japan, where he is interested in the mechanisms regulating stem cell identity.

scholarly journals First person – Marion Lechable and Alexandre Jan

Biology Open ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. bio057034
Keyword(s):  
Cell Biology ◽  
Genetic Model ◽  
Early Career ◽  
Stem Cell Biology ◽  
First Person ◽  
Marie Curie ◽  
Early Career Researchers ◽  
Whole Life Cycle ◽  
Culture Protocol ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Marion Lechable and Alexandre Jan are co-first authors on ‘An improved whole life cycle culture protocol for the hydrozoan genetic model Clytia hemisphaerica’, published in BiO. Marion is a Marie-Curie Sklodowska PhD student (ARDRE doctoral programme) in the lab of Professor Bert Hobmayer at University of Innsbruck, Institute of Zoology, Austria, investigating stem cell biology, regeneration, aging and cnidarians models. Alexandre was an engineer assistant in the lab of Dr Tsuyoshi Momose at Laboratoire de Biologie du Développement, at the Institut de la Mer de Villefranche, France, investigating capture breeding, cnidarians models, gelatinous plankton, improving culturing protocols and regeneration.

scholarly journals First person – Agathe Chaigne

2021 ◽  
Vol 134 (14) ◽  
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Cell Biology ◽  
Three Dimensional ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
University College London ◽  
Molecular Cell Biology ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Agathe Chaigne is first author on ‘ Three-dimensional geometry controls division symmetry in stem cell colonies’, published in JCS. Agathe is a postdoc in the lab of Ewa Paluch at the MRC Laboratory for Molecular Cell Biology (LMCB), University College London, London, UK, investigating the crosstalk between cell division and cell fate transitions during development.

scholarly journals An Interview with Mansi Srivastava

Development ◽  
2022 ◽  
Vol 149 (2) ◽  
Author(s):  
Stefan Galander
Keyword(s):  
Developmental Biology ◽  
Stem Cell ◽  
Cell Biology ◽  
Associate Professor ◽  
Natural Sciences ◽  
Harvard University ◽  
Wound Response ◽  
Stem Cell Biology ◽  
Group Leaders ◽  
Evolutionary Context

Mansi Srivastava is a John L. Loeb Associate Professor of the Natural Sciences at Harvard University. This year, she was awarded the Elizabeth D. Hay New Investigator Award by the Society of Developmental Biology, which recognizes new group leaders who have performed outstanding research in developmental biology during the early stages of their independent career. Mansi's research focusses on investigating wound response and stem cell biology during regeneration in an evolutionary context. We talked to Mansi to discover how she feels about receiving this award, and about her career and her activities outside of the lab.

scholarly journals Physical Exercise and Cardiac Repair: The Potential Role of Nitric Oxide in Boosting Stem Cell Regenerative Biology

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1002
Author(s):  
Fabiola Marino ◽  
Mariangela Scalise ◽  
Eleonora Cianflone ◽  
Luca Salerno ◽  
Donato Cappetta ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Stem Cell ◽  
Physical Exercise ◽  
Cell Biology ◽  
Molecular Mechanisms ◽  
Heart Function ◽  
Stem Cell Biology ◽  
Myocardial Repair ◽  
Beneficial Effects

Over the years strong evidence has been accumulated showing that aerobic physical exercise exerts beneficial effects on the prevention and reduction of cardiovascular risk. Exercise in healthy subjects fosters physiological remodeling of the adult heart. Concurrently, physical training can significantly slow-down or even reverse the maladaptive pathologic cardiac remodeling in cardiac diseases, improving heart function. The underlying cellular and molecular mechanisms of the beneficial effects of physical exercise on the heart are still a subject of intensive study. Aerobic activity increases cardiovascular nitric oxide (NO) released mainly through nitric oxidase synthase 3 activity, promoting endothelium-dependent vasodilation, reducing vascular resistance, and lowering blood pressure. On the reverse, an imbalance between increasing free radical production and decreased NO generation characterizes pathologic remodeling, which has been termed the “nitroso-redox imbalance”. Besides these classical evidence on the role of NO in cardiac physiology and pathology, accumulating data show that NO regulate different aspects of stem cell biology, including survival, proliferation, migration, differentiation, and secretion of pro-regenerative factors. Concurrently, it has been shown that physical exercise generates physiological remodeling while antagonizes pathologic remodeling also by fostering cardiac regeneration, including new cardiomyocyte formation. This review is therefore focused on the possible link between physical exercise, NO, and stem cell biology in the cardiac regenerative/reparative response to physiological or pathological load. Cellular and molecular mechanisms that generate an exercise-induced cardioprotective phenotype are discussed in regards with myocardial repair and regeneration. Aerobic training can benefit cells implicated in cardiovascular homeostasis and response to damage by NO-mediated pathways that protect stem cells in the hostile environment, enhance their activation and differentiation and, in turn, translate to more efficient myocardial tissue regeneration. Moreover, stem cell preconditioning by and/or local potentiation of NO signaling can be envisioned as promising approaches to improve the post-transplantation stem cell survival and the efficacy of cardiac stem cell therapy.

Tradition and Innovation in Cataloguing Medieval Manuscripts

2021 ◽  
Vol 139 (1) ◽  
pp. 32-58
Author(s):  
Orietta Da Rold
Keyword(s):  
New Technologies ◽  
New Technology ◽  
Early Career ◽  
Digital Environment ◽  
Digital Form ◽  
Postgraduate Students ◽  
Medieval Manuscripts ◽  
Early Career Researchers ◽  
History Of ◽  
And Training

Abstract In this essay, I offer a brief history of manuscript cataloguing and some observations on the innovations this practice introduced especially in the digital form. This history reveals that as the cataloguing of medieval manuscripts developed over time, so did the research needs it served. What was often considered traditional cataloguing practices had to be mediated to accommodate new scholarly advance, posing interesting questions, for example, on what new technologies can bring to this discussion. In the digital age, in particular, how do digital catalogues interact with their analogue counterparts? What skills and training are required of scholars interacting with this new technology? To this end, I will consider the importance of the digital environment to enable a more flexible approach to cataloguing. I will also discuss new insights into digital projects, especially the experience accrued by the The Production and Use of English Manuscripts 1060 to 1220 Project, and then propose that in the future cataloguing should be adaptable and shareable, and make full use of the different approaches to manuscripts generated by collaboration between scholars and librarians or the work of postgraduate students and early career researchers.

Sign in / Sign up

Export Citation Format

Share Document