Prognostic Impact of Port-Site Metastasis After Diagnostic Laparoscopy for Epithelial Ovarian Cancer

2016 ◽  
Vol 23 (S5) ◽  
pp. 834-840 ◽  
Author(s):  
Beyhan Ataseven ◽  
Christoph Grimm ◽  
Philipp Harter ◽  
Sebastian Heikaus ◽  
Florian Heitz ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Diagnostic Laparoscopy ◽  
Port Site ◽  
Prognostic Impact ◽  
Port Site Metastasis

scholarly journals Port-site metastasis after diagnostic laparoscopy for presumably benign ruptured ovarian cyst: disseminated intraperitoneal metastasis of a Krukenberg tumor

2004 ◽  
Vol 1 (4) ◽  
pp. 267-269
Author(s):  
Ioannis Mylonas ◽  
Eva-Maria Lochm�ller ◽  
Tanja Greulich ◽  
Bernd Gerber ◽  
Klaus Friese
Keyword(s):  
Ovarian Cyst ◽  
Diagnostic Laparoscopy ◽  
Port Site ◽  
Krukenberg Tumor ◽  
Port Site Metastasis

scholarly journals Early port-site metastasis during neoadjuvant chemotherapy in advanced stage ovarian cancer: report of two cases

2011 ◽  
Vol 22 (1) ◽  
pp. 57 ◽  
Author(s):  
Batuhan Özmen ◽  
Yavuz Emre Şükür ◽  
Cem Somer Atabekoglu ◽  
Aylin Okçu Heper ◽  
Murat Sönmezer ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Port Site ◽  
Advanced Stage ◽  
Port Site Metastasis

The prognostic significance of supradiaphragmatic lymphadenopathy identified on preoperative computed tomography scan in patients undergoing primary cytoreduction for advanced stage epithelial ovarian cancer

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e16512-e16512
Author(s):  
V. Kolev ◽  
S. Mironov ◽  
O. Mironov ◽  
C. Moskowitz ◽  
N. M. Ishill ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ovarian Cancer ◽  
Overall Survival ◽  
Ct Scan ◽  
Epithelial Ovarian Cancer ◽  
Median Survival ◽  
Residual Disease ◽  
Prognostic Significance ◽  
Prognostic Impact ◽  
Preoperative Ct

e16512 Background: It has been hypothesized and shown in animal studies that the supradiaphragmatic lymph nodes serve as the principal nodes for lymphatic drainage of the entire peritoneal cavity. The purpose of this study was to determine the prognostic significance of enlarged supra-diaphragmatic nodes noted on preoperative computed tomography (CT) scan in patients with advanced epithelial ovarian cancer (EOC). Methods: We performed a retrospective chart review of all patients (pts) with FIGO stage III and IV EOC who had preoperative CT scans of the supradiaphragmatic region and primary cytoreductive surgery at our institution between 1997 and 2004. All scans were retrospectively reviewed by one board-certified radiologist (SM). To evaluate survival, Kaplan-Meier methods were used, with log rank Pvalues for comparisons. Results: A total of 212 eligible pts who underwent attempted primary cytoreduction followed by platinum-based systemic chemotherapy were identified for evaluation. With a median follow-up time of 52 mos, there were 135 deaths and a median overall survival of 48 mos (95% CI: 44–53). Of the 212 pts, 44 (21%) had supradiaphragmatic adenopathy with nodes >1 cm, while 168 (79%) did not have adenopathy in this distribution. None of the 44 pts with adenopathy had the enlarged nodes removed at primary cytoreduction. The median survival was 49 mos for pts with and 48 mos for patients without adenopathy (p = 0.46). In total, 155 (73%) patients underwent optimal cytoreduction (residual disease ≤ 1 cm). In the optimally cytoreduced pts, the median survival for the 125 pts without supradiaphragmatic adenopathy was 52 mos (95%CI: 45–59) compared to 51mos (95%CI: 41–58) for the 30 pts with supradiaphragmatic adenopathy (p = 0.33). Conclusions: Although a previous study has shown that supradiaphragmatic adenopathy was associated with poorer overall survival in EOC patients, our study did not confirm these findings. In our study, enlarged supradiaphragmatic nodes noted on preoperative CT scan did not have significant prognostic impact and therefore their clinical significance remains uncertain. No significant financial relationships to disclose.

scholarly journals Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer

2016 ◽  
Vol 9 (1) ◽  
Author(s):  
Sebastian Lundgren ◽  
Jonna Berntsson ◽  
Björn Nodin ◽  
Patrick Micke ◽  
Karin Jirström
Keyword(s):  
Ovarian Cancer ◽  
B Cells ◽  
Epithelial Ovarian Cancer ◽  
Plasma Cells ◽  
Prognostic Impact

Port site metastasis after diagnostic laparoscopy for upper gastrointestinal tract malignancies: An uncommon entity

2002 ◽  
Vol 9 (7) ◽  
pp. 632-636 ◽  
Author(s):  
Margo Shoup ◽  
Murray F. Breenan ◽  
Martin S. Karpeh ◽  
Susan M. Gillern ◽  
Ross L. McMahon ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Laparoscopy ◽  
Port Site ◽  
Upper Gastrointestinal Tract ◽  
Port Site Metastasis ◽  
Upper Gastrointestinal

scholarly journals Survival in Advanced-Stage Epithelial Ovarian Cancer Patients with Cardiophrenic Lymphadenopathy Who Underwent Cytoreductive Surgery: A Systematic Review and Meta-Analysis

Cancers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 5017
Author(s):  
Malika Kengsakul ◽  
Gatske M. Nieuwenhuyzen-de Boer ◽  
Anna H. J. Bijleveld ◽  
Suwasin Udomkarnjananun ◽  
Stephen J. Kerr ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cytoreductive Surgery ◽  
Perioperative Complications ◽  
Meta Analysis ◽  
Preoperative Imaging ◽  
Cochrane Library ◽  
Prognostic Impact ◽  
Advanced Stage ◽  
Increased Risk

Purpose: To evaluate the clinical outcomes of enlarged cardiophrenic lymph node (CPLN) in advanced-stage epithelial ovarian cancer (AEOC) patients who underwent cytoreductive surgery. Methods: The Embase, Medline, Web of Science, Cochrane Library, and Google Scholar databases were searched for articles from the database inception to June 2021. Meta-analysis was conducted to determine the prognostic impact of surgical outcome, postoperative complication, and survival using random-effects models. Results: A total of 15 studies involving 727 patients with CPLN adenopathy and 981 patients without CPLN adenopathy were included. The mean size of preoperative CPLN was 9.1± 3.75 mm. Overall, 82 percent of the resected CPLN were histologically confirmed pathologic nodes. Surgical outcomes and perioperative complications did not differ between both groups. The median OS time was 42.7 months (95% CI 10.8–74.6) versus 47.3 months (95% CI 23.2–71.2), in patients with and without CPLN adenopathy, respectively. At 5 years, patients with CPLN adenopathy had a significantly increased risk of disease recurrence (HR 2.14, 95% CI 1.82–2.52, p < 0.001) and dying from the disease (HR 1.74, 95% CI 1.06–2.86, p = 0.029), compared with those without CPLN adenopathy. CPLN adenopathy was significantly associated with ascites (OR 3.30, 95% CI 1.90–5.72, p < 0.001), pleural metastasis (OR 2.58, 95% CI 1.37–4.82, p = 0.003), abdominal adenopathy (OR 2.30, 95% CI 1.53–3.46, p < 0.001) and extra-abdominal metastasis (OR 2.30, 95% CI 1.61–6.67, p = 0.001). Conclusions: Enlarged CPLN in preoperative imaging is highly associated with metastatic involvement. Patients with CPLN adenopathy had a lower survival rate, compared with patients without CPLN adenopathy. Further randomized controlled trials should be conducted to definitively demonstrate whether CPLN resection at the time of cytoreductive surgery is beneficial.

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