Synthesis of C3-Symmetric Macrocyclic Triimines from Monomers having Boc-Protected Amine and Formyl Group

2022 ◽  
Author(s):  
Yu Moriya ◽  
Masahiro Yamanaka ◽  
Keiji Mori
Keyword(s):  
Formyl Group

The influence of structural factors and the solvent on the nature of the enolization of the formyl group

1971 ◽  
Vol 20 (4) ◽  
pp. 655-660
Author(s):  
S. T. Ioffe ◽  
K. V. Vatsuro ◽  
P. V. Petrovskii ◽  
M. I. Kabachnik
Keyword(s):  
Structural Factors ◽  
Formyl Group

The chemistry of pyrrolic compounds. XXV. The chemistry of acetal and thioacetal derivatives of pyrrolic systems

1974 ◽  
Vol 27 (2) ◽  
pp. 357 ◽  
Author(s):  
PS Clezy ◽  
CJR Fookes ◽  
DYK Lau ◽  
AW Nichol ◽  
GA Smythe
Keyword(s):  
Formyl Group ◽  
Derivatives Of

The synthesis of acetal and thioacetal derivatives of simple pyrroles is described. Methods are reported which allow the use of the thioacetal function as a means of protecting a formyl group in a pyrrolic molecule during the preparation of a dipyrrylmethane. By this procedure certain α-formyldipyrrylmethanes, not accessible by other methods, have been obtained.

scholarly journals The application of formyl group activation of bromopyrrole esters to formal syntheses of lycogarubin C, permethyl storniamide A and lamellarin G trimethyl ether

Tetrahedron ◽  
2014 ◽  
Vol 70 (52) ◽  
pp. 9759-9767 ◽  
Author(s):  
John T. Gupton ◽  
Nakul Telang ◽  
Jon Patteson ◽  
Kristin Lescalleet ◽  
Scott Yeudall ◽  
...  
Keyword(s):  
Formyl Group ◽  
Trimethyl Ether

Formyl group modification of chlorophylla: a major evolutionary mechanism in oxygenic photosynthesis

2012 ◽  
Vol 36 (3) ◽  
pp. 521-527 ◽  
Author(s):  
MARTIN SCHLIEP ◽  
GERMÁN CAVIGLIASSO ◽  
ROSANNE G. QUINNELL ◽  
ROBERT STRANGER ◽  
ANTHONY W. D. LARKUM
Keyword(s):  
Oxygenic Photosynthesis ◽  
Formyl Group ◽  
Evolutionary Mechanism ◽  
Group Modification

scholarly journals Structure of putative tumor suppressor ALDH1L1

2022 ◽  
Vol 5 (1) ◽  
Author(s):  
Yaroslav Tsybovsky ◽  
Valentin Sereda ◽  
Marcin Golczak ◽  
Natalia I. Krupenko ◽  
Sergey A. Krupenko
Keyword(s):  
Tumor Suppressor ◽  
Aldehyde Dehydrogenase ◽  
Functional Domain ◽  
Formyl Group ◽  
Carrier Proteins ◽  
Catalytic Domains ◽  
Putative Tumor Suppressor ◽  
Enzymatic Systems ◽  
Domain Interactions ◽  
Intermediate Domain

AbstractPutative tumor suppressor ALDH1L1, the product of natural fusion of three unrelated genes, regulates folate metabolism by catalyzing NADP+-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and CO2. Cryo-EM structures of tetrameric rat ALDH1L1 revealed the architecture and functional domain interactions of this complex enzyme. Highly mobile N-terminal domains, which remove formyl from 10-formyltetrahydrofolate, undergo multiple transient inter-domain interactions. The C-terminal aldehyde dehydrogenase domains, which convert formyl to CO2, form unusually large interfaces with the intermediate domains, homologs of acyl/peptidyl carrier proteins (A/PCPs), which transfer the formyl group between the catalytic domains. The 4′-phosphopantetheine arm of the intermediate domain is fully extended and reaches deep into the catalytic pocket of the C-terminal domain. Remarkably, the tetrameric state of ALDH1L1 is indispensable for catalysis because the intermediate domain transfers formyl between the catalytic domains of different protomers. These findings emphasize the versatility of A/PCPs in complex, highly dynamic enzymatic systems.

Aldehyde-Substituted Donor–Acceptor-Type Dithienylethenes as Novel Building Blocks for Photochromic Materials

2018 ◽  
Vol 42 (10) ◽  
pp. 531-534 ◽  
Author(s):  
Yangyang Wang ◽  
Mengna Li ◽  
Yufei Song ◽  
Ming Qin ◽  
Xuehui Li ◽  
...  
Keyword(s):  
Dft Calculations ◽  
Near Infrared ◽  
Building Blocks ◽  
Formyl Group ◽  
Photochromic Properties ◽  
H Nmr ◽  
Donor Acceptor ◽  
Group Functions ◽  
Photochromic Materials ◽  
C Nmr

Two novel donor–π–acceptor-type dithienylethene derivatives, in which the triphenylamine group acts as electron donor and the formyl group functions as electron acceptor, have been developed. Their structures were confirmed by 1H NMR, 13C NMR and HRMS (ESI). Investigation of their photochromic properties indicated that they had good photochromic behaviour and excellent fatigue resistance on irradiation with UV or visible light. DFT calculations further validated these experimental results for photochromic behaviour. Moreover, these compounds can be utilised as versatile building blocks to construct novel near-infrared photochromic materials.

Reduction of the Formyl Group of Zinc Pheophorbide b in vitro and in vivo: a Model for the Chlorophyll b to a Transformation

1996 ◽  
Vol 51 (3-4) ◽  
pp. 185-194 ◽  
Author(s):  
Verena Scheumann ◽  
Michael Helfrich ◽  
Siegrid Schoch ◽  
Wolfhart Rüdiger
Keyword(s):  
Nmr Spectroscopy ◽  
Chlorophyll A ◽  
Chemical Reduction ◽  
Chlorophyll B ◽  
Formyl Group ◽  
Pheophorbide A ◽  
Pheophytin A ◽  
H Nmr

Abstract The chemical reduction of the formyl group of pheophorbide b with sodium cyanoborohy­ dride in methanol leads to 71-methoxy-and 71-hydroxy-pheophorbide a. The same reaction with zinc pheophorbide b yields in addition zinc pheophorbide a. This was characterized by mass and 1H -NMR spectroscopy. Infiltration of zinc pheophorbides a and b and of zinc 71-hydroxy-pheophorbide a into etiolated oat leaves yielded phytylated products. The best yield in the esterification was obtained with 71-hydroxy-pheophorbide a. Analysis of the products revealed the formation of zinc pheophytin a from all infiltrated compounds. The significance for the transformation of chlorophyll b into chlorophyll a is discussed.

scholarly journals First Total Synthesis and Investigation of the X-ray Crystal Structure of the Pyrano[3,2-a]carbazole Alkaloid Clausenalansine A

Synthesis ◽  
2020 ◽  
Vol 53 (02) ◽  
pp. 359-364
Author(s):  
Hans-Joachim Knölker ◽  
Valerie Lösle ◽  
Olga Kataeva
Keyword(s):  
Crystal Structure ◽  
Total Synthesis ◽  
Lewis Acid ◽  
Oxidative Cyclization ◽  
Formyl Group ◽  
Pyran Ring ◽  
X Ray ◽  
Synthetic Strategy

AbstractWe describe the first total synthesis of the recently discovered pyrano[3,2-a]carbazole alkaloid clausenalansine A. The synthetic strategy for the construction of this formylpyrano[3,2-a]carbazole is based on a sequence of Buchwald–Hartwig coupling, palladium(II)-catalyzed oxidative cyclization, Lewis acid promoted annulation of the pyran ring, and chemoselective oxidation of a methyl to a formyl group.

scholarly journals Orthoamide, LXIII [1]. Tris(dichlormethyl)amin, ein neues breit anwendbares Formylierungsmittel für Aromaten / Orthoamides, LXIII [1]. Tris(dichloromethyl)amine, a New Formylating Reagent for Aromatic Compounds of Wide Scope

2006 ◽  
Vol 61 (4) ◽  
pp. 448-463 ◽  
Author(s):  
Willi Kantlehner ◽  
Ralf Kreß ◽  
Franziska Zschach ◽  
Jens Vetter ◽  
Georg Ziegler ◽  
...  
Keyword(s):  
Aluminum Chloride ◽  
Aromatic Compounds ◽  
Lewis Acids ◽  
Aluminium Chloride ◽  
Aromatic Nucleus ◽  
Wide Scope ◽  
Formyl Group ◽  
Reaction Conditions ◽  
Optimal Reaction

The reagent system formed from tris(dichloromethyl)amine (5) and aluminium chloride allows the formylation of aromatic compounds. The scope of the method is comparable with that of the Olah formylation and the Groß-Rieche procedure, since benzene and even chlorobenzene can be formylated. One formyl group is transferred from 5 to the aromatic nucleus. In order to find optimal reaction conditions, the molar amounts of aromatic compounds, 5 and aluminum chloride were varied as well as reaction temperatures and solvents. The activation of 5 with other Lewis acids is also described

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