scholarly journals Spectrophotometric Determination of Rifampicin through Chelate Formation and Charge Transfer Complexation in Pharmaceutical Preparation and Biological Fluids

2006 ◽  
Vol 54 (8) ◽  
pp. 1107-1112 ◽  
Author(s):  
Susan Sadeghi ◽  
Esmat Karimi
Keyword(s):  
Charge Transfer ◽  
Spectrophotometric Determination ◽  
Biological Fluids ◽  
Pharmaceutical Preparation ◽  
Chelate Formation ◽  
Charge Transfer Complexation

Spectrophotometric determination of some corticosteroid drugs through charge-transfer complexation

The Analyst ◽  
1984 ◽  
Vol 109 (11) ◽  
pp. 1417 ◽  
Author(s):  
Magda M. Ayad ◽  
Saied Belal ◽  
Sobhi M. El Adl ◽  
Afaf A. Al Kheir
Keyword(s):  
Charge Transfer ◽  
Spectrophotometric Determination ◽  
Corticosteroid Drugs ◽  
Charge Transfer Complexation

scholarly journals Spectrophotometric Determination of Sulfamethoxazole Based on Charge-Transfer Complexation with Sodium Nitroprusside

2017 ◽  
Vol 30 (3) ◽  
pp. 102
Author(s):  
Tariq Y. Mahmoud ◽  
Sarmad B. Dikran ◽  
Alaa K. Mohammed
Keyword(s):  
Charge Transfer ◽  
Sodium Nitroprusside ◽  
Pharmaceutical Preparation ◽  
Molar Absorptivity ◽  
Amine Hydrochloride ◽  
Colored Complex ◽  
Central Composite Experimental Design ◽  
Charge Transfer Complexation ◽  
Good Agreement

   A simple, accurate and precise spectrophotometric method has been developed for the analysis of sulfamethoxazole (SMZ) in pure form and pharmaceutical preparation. The method involves a direct charge transfer complexation of sulfamethoxazole (SMZ) with sodium nitroprusside (SNP) in alkaline medium and the presence of hydroxyl amine hydrochloride. Variables affecting the formation of the formed orange colored complex were optimized following two approaches univariate and central composite experimental design (CCD) multivariate. Under optimum recommended conditions, the formed complex exhibits λmax at 512 nm and the method conforms Beer's law for SMZ concentration in the range of 5.0-150.0 (µg.mL-1) with molar absorptivity 1.139×103 L.mol-1.cm-1, and r = 0.9997. Analysis of SMZ pharmaceutical dosages shows a good agreement with the real amounts.

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