AbstractThe use of iron catalysis to enable reactions with diazo compounds has emerged as a valuable tool to forge carbon–carbon or carbon–heteroatom bonds. While diazo compounds are often encountered with toxic and expensive metal catalysts, such as Rh, Ru, Pd, Ir, and Cu, a resurgence of Fe catalysis has been observed. This short review will showcase and highlight the recent advances in iron-mediated reactions of diazo compounds.1 Introduction2 Insertion Reactions2.1 Insertion into B–H Bonds2.2 Insertion into Si–H Bonds2.3 Insertion into N–H Bonds2.4 Insertion into S–H bonds3 Ylide Formation and Subsequent Reactions3.1 Doyle–Kirmse Rearrangement3.2 [1,2]-Stevens and Sommelet–Hauser Rearrangements3.3 Olefination Reactions3.4 Cycloaddition Reactions3.5 gem-Difluoroalkenylation4 Three-Component Reactions5 Miscellaneous6 Conclusion
Development of Novel Methodology Using Diazo Compounds and Metal Catalysts
