scholarly journals Studies on Bioactive Substances in the Chinese Material Medicines (〓 ?? ?? ?? ) Used for Arthritic Diseases in Traditional Chinese Medicine. I. Anti-inflammatory and Analgesic Effect of Chinese Material Medicines Used for Arthritic Diseases

1985 ◽  
Vol 105 (9) ◽  
pp. 845-847 ◽  
Author(s):  
TAKUO KOSUGE ◽  
MASAMI YOKOTA ◽  
KIYOSHI SUGIYAMA ◽  
TOSUKE YAMAMOTO ◽  
TAKAKI MURE ◽  
...  
2021 ◽  
Author(s):  
Rongrong Zhang ◽  
Shuai Shao ◽  
Yingxin Shen ◽  
Jiaming Sun ◽  
Songlan Piao ◽  
...  

Abstract Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by an itchy and scaly rash. Compound traditional Chinese medicine dermatitis ointment (CTCMDO) is a traditional classics aimed at AD composed of a mixture of extracts from five plants known to have anti-inflammatory and antiallergic effects. Materials and methods: In this study, we used HPLC and LC/MS to analyze the effective components of CTCMDO in detail and establish its HPLC fingerprint analysis. On this basis, this article studied the anti-inflammatory and antipruritic activities of CTCMDO in the treatment of DNCB-induced AD in mice.Results: Through comparison with literature data, a total of 43 compounds were identified, including phenylpropionic acid compounds; alkaloid compounds; curcumin compounds and lignans. On this basis, a fingerprint with 17 common peaks was established. In AD-like mice, CTCMDO treatment suppressed the scratching behavior induced by DNCB in a dose-dependent manner and inhibited the production of Th1/2 cytokines in serum. CTCMDO treatment reversed the up regulation of P substance levels of itch-related genes in the skin. Furthermore, CTCMDO suppressed the phosphorylation of JNK、ERK and p38 in the skin. Conclusion: In all, our work indicated that CTCMDO can signifificantly attenuate the pathological alterations of Th1/2 cytokines and itch-related mediators, and inhibit the phosphorylation of MAPKs to treat AD.


2021 ◽  
Vol 14 (1) ◽  
pp. 95-98
Author(s):  
Siukan Law ◽  
Chuiman Lo ◽  
Jie Han ◽  
Albert Wingnang Leung ◽  
Chuanshan Xu

Indigowoad Root is traditional Chinese medicine. It belongs to the “cool blood herb” category which has been used for anti-inflammatory and anti-infections situations regarding the Yin-Yang theory. Hydrogel is one of the biomaterials for drug delivery that provided a large surface area and permeability, enhanced the characteristics of solubility and absorption of traditional Chinese medicine, for example, curcumin. Based on the pieces of evidence, these might have some possible methods for the synthesis of Indigowoad Root hydrogel on skincare in the future.


2020 ◽  
Vol 8 (4) ◽  
pp. 715-726 ◽  
Author(s):  
Kangkang Zhi ◽  
Jiacheng Wang

A supramolecular self-assembled natural product gel from liquidambaric acid in traditional Chinese medicine with inherent anti-inflammatory activity for drug delivery was constructed.


2019 ◽  
Vol 11 (3) ◽  
pp. 309-319
Author(s):  
Mohamad Hesam SHAHRAJABIAN ◽  
Wenli SUN ◽  
Qi CHENG

Ginger (Zingiber officinale) has been used as a spice and a medicine for over 200 years in traditional Chinese medicine. Ginger is an important plant with several medicinal and nutritional values used in Asian and Chinese tradition medicine. Ginger and its general compounds such as Fe, Mg, Ca, vitamin C, flavonoids, phenolic compounds (gingerdiol, gingerol, gingerdione and shogaols), sesquiterpenes, paradols has long been used as an herbal medicine to treat various symptoms including vomiting, pain, cold symptoms and it has been shown to have anti-inflammatory, anti-apoptotic, anti-tumor activities, anti-pyretic, anti-platelet, anti-tumourigenic, anti-hyperglycaemic, antioxidant anti-diabetic, anti-clotting and analgesic properties, cardiotonic, cytotoxic. It has been widely used for arthritis, cramps, sprains, sore throats, rheumatism, muscular aches, pains, vomiting, constipation, indigestion, hypertension, dementia, fever and infectious diseases. Ginger leaves have also been used for food flavouring and Asian traditional medicine especially in China. Ginger oil also used as food flavouring agent in soft drink, as spices in bakery products, in confectionary items, pickles, sauces and as a preservatives. Ginger is available in three forms, namely fresh root ginger, preserved ginger and dried ginger. The pharmacological activities of ginger were mainly attributed to its active phytocompounds 6-gingerol, 6-shogaol, zingerone beside other phenolics and flavonoids. Gingerol and shogaol in particular, is known to have anti-oxidant and anti-inflammatory properties. In both traditional Chinese medicine, and modern China, Ginger is used in about half of all herbal prescriptions. Traditional medicinal plants are often cheaper, locally available and easily consumable raw and as simple medicinal preparations. The obtained findings suggest potential of ginger extract as an additive in the food and pharmaceutical industries.


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