scholarly journals Pharmacological Uses and Health Benefits of Ginger (Zingiber officinale) in Traditional Asian and Ancient Chinese Medicine, and Modern Practice

2019 ◽  
Vol 11 (3) ◽  
pp. 309-319
Author(s):  
Mohamad Hesam SHAHRAJABIAN ◽  
Wenli SUN ◽  
Qi CHENG
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Soft Drink ◽  
Zingiber Officinale ◽  
Modern China ◽  
Ginger Extract ◽  
Nutritional Values ◽  
Anti Oxidant ◽  
Pharmaceutical Industries ◽  
Anti Inflammatory

Ginger (Zingiber officinale) has been used as a spice and a medicine for over 200 years in traditional Chinese medicine. Ginger is an important plant with several medicinal and nutritional values used in Asian and Chinese tradition medicine. Ginger and its general compounds such as Fe, Mg, Ca, vitamin C, flavonoids, phenolic compounds (gingerdiol, gingerol, gingerdione and shogaols), sesquiterpenes, paradols has long been used as an herbal medicine to treat various symptoms including vomiting, pain, cold symptoms and it has been shown to have anti-inflammatory, anti-apoptotic, anti-tumor activities, anti-pyretic, anti-platelet, anti-tumourigenic, anti-hyperglycaemic, antioxidant anti-diabetic, anti-clotting and analgesic properties, cardiotonic, cytotoxic. It has been widely used for arthritis, cramps, sprains, sore throats, rheumatism, muscular aches, pains, vomiting, constipation, indigestion, hypertension, dementia, fever and infectious diseases. Ginger leaves have also been used for food flavouring and Asian traditional medicine especially in China. Ginger oil also used as food flavouring agent in soft drink, as spices in bakery products, in confectionary items, pickles, sauces and as a preservatives. Ginger is available in three forms, namely fresh root ginger, preserved ginger and dried ginger. The pharmacological activities of ginger were mainly attributed to its active phytocompounds 6-gingerol, 6-shogaol, zingerone beside other phenolics and flavonoids. Gingerol and shogaol in particular, is known to have anti-oxidant and anti-inflammatory properties. In both traditional Chinese medicine, and modern China, Ginger is used in about half of all herbal prescriptions. Traditional medicinal plants are often cheaper, locally available and easily consumable raw and as simple medicinal preparations. The obtained findings suggest potential of ginger extract as an additive in the food and pharmaceutical industries.

scholarly journals Anti-Inflammatory Effects of 81 Chinese Herb Extracts and Their Correlation with the Characteristics of Traditional Chinese Medicine

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Chang-Liang Chen ◽  
Dan-Dan Zhang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Nitrogen Oxide ◽  
Chinese Herb ◽  
Zingiber Officinale ◽  
Chinese Herbs ◽  
No Production ◽  
Forsythia Suspensa ◽  
Anti Inflammatory ◽  
Daphne Genkwa

Inducible nitrogen oxide synthase (iNOS) is the primary contributor of the overproduction of nitric oxide and its inhibitors have been actively sought as effective anti-inflammatory agents. In this study, we prepared 70% ethanol extracts from 81 Chinese herbs. These extracts were subsequently evaluated for their effect on nitrogen oxide (NO) production and cell growth in LPS/IFNγ-costimulated and unstimulated murine macrophage RAW264.7 cells by Griess reaction and MTT assay. Extracts ofDaphne genkwaSieb.et Zucc,Caesalpinia sappanL.,Iles pubescensHook.et Arn,Forsythia suspensa(Thunb.) Vahl,Zingiber officinaleRosc,Inula japonicaThunb., andLigusticum chuanxiongHort markedly inhibited NO production (inhibition > 90% at 100 μg/mL). Among active extracts (inhibition > 50% at 100 μg/mL),Rubia cordifoliaL.,Glycyrrhiza glabraL.,Iles pubescensHook.et Arn,Nigella glanduliferaFreyn et Sint,Pueraria lobata(Willd.) Ohwi, andScutellaria barbataD. Don displayed no cytotoxicity to unstimulated RAW246.7 cells while increasing the growth of LPS/IFNγ-costimulated cells. By analyzing the correlation between their activities and their Traditional Chinese Medicine (TCM) characteristics, herbs with pungent flavor displayed potent anti-inflammatory capability. Our study provides a series of potential anti-inflammatory herbs and suggests that herbs with pungent flavor are candidates of effective anti-inflammatory agents.

scholarly journals STUDY OF CHINESE HONEY LOCUST (GLEDITSIA SINENSIS) AND SHALLOT (ALLIUM ASCALONICUM L.) FOR INTEGRATE TRADITIONAL CHINESE MEDICINE INTO OTHER COUNTRIES' MEDICINE IN ORDER TO IMPROVE PUBLIC HEALTH

2020 ◽  
Vol 36 (2) ◽  
pp. 8-14
Author(s):  
M. H. Shahrajabian ◽  
W. Sun ◽  
M. Khoshkharam ◽  
H. Shen ◽  
Q. Cheng
Keyword(s):  
Public Health ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Great Success ◽  
Root Bark ◽  
Triterpenoid Saponins ◽  
Pharmaceutical Industries ◽  
Honey Locust ◽  
Gleditsia Sinensis ◽  
Anti Inflammatory

The population health is an important component of the country development, since the working capacity and workers' safety in the workplace depends on their health status. Toxic substances that are used the manufacturing process often cause allergies, inflammatory processes of the skin and internal organs, sometimes diabetes and cancer. To strengthen immunity and improve the health of workers, traditional Chinese medicine, which has achieved great success at present, can be recommended. The aim of this manuscript is review of health benefits and pharmaceutical impacts of Chinese honey locust and shallot. Literature search was conducted in Medline, Research Gate, Scopus, PubMed and Google Scholar Databases. The keywords were Chinese honeylocust, shallot, traditional Chinese medicine, Asian medicine and modern pharmaceutical Sciences. Gleditsia sinensis Lam. (G. sinensis) is a perennial arbour spread in most parts of the world, especially in China. It is a classical traditional Chinese medical herb. All relevant papers in the English language of researchers from different countries were collected. The most important benefits of shallots are high source of antioxidants, improve heart health, cancer prevention, and diabetes, anti-inflammatory, antimicrobial, might help fight obesity, and help to prevent or treat allergies. The most important components of Gleditsia sinensis are triterpenoid saponins, triterpenes, flavonoids, alkaloids, phenolics, sterols, and their important derivatives are responsible for tremendous medicinal effects. It has been reported that Gleditsia sinensis Lam thorn (GST) possesses a wide spectrum of pharmacological activities such as antioxidant, anti-inflammatory, anti-microbial, anti-angiogenic and anti-tumor effects. Its fruit is antibacterial, antifungal, antitussive, astringent, emetic, expectorant, haemostatic and stimulant. The seed is emetic, expectorant, decongestant and purgative, and its root bark is both anthelmintic and antifebrile. The obtained findings suggest potential of Shallot and Chinese honey locust in both food and pharmaceutical industries. The demand for shallot products is increasing every year with increase population growth and food industries. More clinical studies may necessary to uncover the numerous substances and their effects in shallot that contribute to public health.

scholarly journals Compound Traditional Chinese Medicine Dermatitis Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules in AD

2021 ◽  
Author(s):  
Rongrong Zhang ◽  
Shuai Shao ◽  
Yingxin Shen ◽  
Jiaming Sun ◽  
Songlan Piao ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Inflammatory Responses ◽  
Dependent Manner ◽  
Inflammatory Skin Disease ◽  
Fingerprint Analysis ◽  
Hplc Fingerprint ◽  
Effective Components ◽  
Anti Inflammatory ◽  
Dose Dependent

Abstract Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by an itchy and scaly rash. Compound traditional Chinese medicine dermatitis ointment (CTCMDO) is a traditional classics aimed at AD composed of a mixture of extracts from five plants known to have anti-inflammatory and antiallergic effects. Materials and methods: In this study, we used HPLC and LC/MS to analyze the effective components of CTCMDO in detail and establish its HPLC fingerprint analysis. On this basis, this article studied the anti-inflammatory and antipruritic activities of CTCMDO in the treatment of DNCB-induced AD in mice.Results: Through comparison with literature data, a total of 43 compounds were identified, including phenylpropionic acid compounds; alkaloid compounds; curcumin compounds and lignans. On this basis, a fingerprint with 17 common peaks was established. In AD-like mice, CTCMDO treatment suppressed the scratching behavior induced by DNCB in a dose-dependent manner and inhibited the production of Th1/2 cytokines in serum. CTCMDO treatment reversed the up regulation of P substance levels of itch-related genes in the skin. Furthermore, CTCMDO suppressed the phosphorylation of JNK、ERK and p38 in the skin. Conclusion: In all, our work indicated that CTCMDO can signifificantly attenuate the pathological alterations of Th1/2 cytokines and itch-related mediators, and inhibit the phosphorylation of MAPKs to treat AD.

A Literature Review on Indigowoad Root Hydrogel Development for Skincare

2021 ◽  
Vol 14 (1) ◽  
pp. 95-98
Author(s):  
Siukan Law ◽  
Chuiman Lo ◽  
Jie Han ◽  
Albert Wingnang Leung ◽  
Chuanshan Xu
Keyword(s):  
Drug Delivery ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Literature Review ◽  
Surface Area ◽  
Large Surface Area ◽  
The Future ◽  
Yin Yang ◽  
Anti Inflammatory

Indigowoad Root is traditional Chinese medicine. It belongs to the “cool blood herb” category which has been used for anti-inflammatory and anti-infections situations regarding the Yin-Yang theory. Hydrogel is one of the biomaterials for drug delivery that provided a large surface area and permeability, enhanced the characteristics of solubility and absorption of traditional Chinese medicine, for example, curcumin. Based on the pieces of evidence, these might have some possible methods for the synthesis of Indigowoad Root hydrogel on skincare in the future.

Retracted Article: A self-assembled supramolecular natural product gel from liquidambaric acid in traditional Chinese medicine with inherent anti-inflammatory activity for drug delivery

2020 ◽  
Vol 8 (4) ◽  
pp. 715-726 ◽  
Author(s):  
Kangkang Zhi ◽  
Jiacheng Wang
Keyword(s):  
Drug Delivery ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Natural Product ◽  
Inflammatory Activity ◽  
Retracted Article ◽  
Anti Inflammatory ◽  
Self Assembled

A supramolecular self-assembled natural product gel from liquidambaric acid in traditional Chinese medicine with inherent anti-inflammatory activity for drug delivery was constructed.

scholarly journals Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Xiangpeng Kong ◽  
Zhicong Chen ◽  
Yingjie Xia ◽  
Etta Y. L. Liu ◽  
Haiqin Ren ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Proinflammatory Cytokines ◽  
Blood Circulation ◽  
Nuclear Translocation ◽  
Total Alkaloids ◽  
Tnf Α ◽  
Different Types ◽  
Anti Inflammatory ◽  
Chromatographic Peaks

Corydalis Rhizoma (CR) is a commonly used traditional Chinese medicine for its potency in activating blood circulation and analgesia. In clinic, CR extracts or components are commonly used in the treatment of myocardial ischemia, rheumatism, and dysmenorrhea with different types of inflammation. However, due to different mechanism of pain and inflammation, the anti-inflammatory property of CR has not been fully revealed. Here, the major chromatographic peaks of CR extracts in different extracting solvents were identified, and the anti-inflammatory activities of CR extracts and its major alkaloids were evaluated in LPS-treated macrophages by determining expressions of proinflammatory cytokines, IκBα and NF-κB. The most abundant alkaloid in CR extract was dehydrocorydaline, having >50% of total alkaloids. Besides, the anti-inflammatory activities of dehydrocorydaline and its related analogues were demonstrated. The anti-inflammatory roles were revealed in LPS-treated cultured macrophages, including (i) inhibiting proinflammatory cytokines release, for example, TNF-α, IL-6; (ii) suppressing mRNA expressions of proinflammatory cytokines; (iii) promoting IκBα expression and suppressing activation of NF-κB transcriptional element; and (iv) reducing the nuclear translocation of NF-κB. The results supported that dehydrocorydaline was the major alkaloid in CR extract, which, together with its analogous, accounted the anti-inflammatory property of CR.

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