Nutritional Supplements for the Treatment and Prevention of Sports-Related Concussion — Omega 3 Fatty Acids

2018 ◽  
Vol 17 (3) ◽  
pp. 103-104
Author(s):  
Jonathan M. Oliver ◽  
Anthony J. Anzalone ◽  
Margaret T. Jones ◽  
K. Michele Kirk ◽  
David A. Gable ◽  
...  
2017 ◽  
Vol 1 (1) ◽  
pp. 1-12
Author(s):  
Christoph Baumann ◽  
Christian Willaschek ◽  
Tuende Kertess-Szlaninka ◽  
Lang Johanna ◽  
Reiner Buchhorn

Objective: To assess the effect of different treatment approaches on the course of anorexia nervosa (AN) over time. Methods: The subjects were 27 hospitalized AN patients. In our retrospective analysis we compared weight gain in two groups. While one group was treated with a standard oral refeeding protocol (historical control) through January 2013 (N=16), the second group (highly standardized refeeding protocol) received a high energy liquid nutrition and nutritional supplements including omega-3 fatty acids (N=11). Results: On admission, the two groups were comparable in terms of height, weight, age and heart rate. At the end of our monitoring time frame of 25 days, weight gain was 121.4% higher in the highly standardized refeeding protocol group than in the historical control group (66.5 ±52.4 vs 147.3 ±55.7 grams/day; t-Test p=0.004; CI95%: 29.3-132.2). A carbohydrate rich diet clearly improved weight gain if high energy liquid nutrition was replaced by the diet according the patient’s own wishes. About 45% of our patients stated they were vegetarians at admission. However, we could not identify a vegetarian diet as a statistically significant negative prognostic factor for weight gain. Conclusion: The highly standardized refeeding protocol seems to be helpful in malnourished AN patients to improve weight gain without enhancing the risk of a refeeding syndrome. However, further studies with greater number of patients are needed to confirm the effectiveness of our standardized treatment protocol.


Author(s):  
Rebecca Glynne Long

Depression is an extremely costly and debilitation condition. Researchers have failed to find a single causal mechanism, concluding that several genetic and environmental factors contribute to the etiology of depression. However, researchers cannot ignore the drastic dietary changes that have occurred since the onset of industrialization. Deficiencies in certain critical nutrients may put individuals at risk for depression. Research in recent years has turned to deficiencies in omega-3 fatty acids to help explain increased rates of depression over the course of the 20th century. This paper first explains how the industrialization of agricultural production has served to significantly alter our intake of omega-3 fatty acids. Next, this paper examines a suggested causal mechanism linking omega-3 fatty acids deficiencies to depression: omega-3 fatty acids deficiencies contribute to a heightened inflammatory response resulting from prolonged activation of the immune system. Inflammation in turn produces sickness behaviors that mirror depressive symptoms. Lastly, this paper will focus on a brief review of the literature studying the effects of omega-3 fatty acids deficiencies in depressed individuals. Research investigating the role of omega-3 fatty acid deficiencies in depressed patients has the potential to lead to the development of more efficacious treatment and prevention options.


Author(s):  
Hadeer Zakaria ◽  
Tarek M. Mostafa ◽  
Gamal A. El-Azab ◽  
Nagy AH Sayed-Ahmed

Abstract. Background: Elevated homocysteine levels and malnutrition are frequently detected in hemodialysis patients and are believed to exacerbate cardiovascular comorbidities. Omega-3 fatty acids have been postulated to lower homocysteine levels by up-regulating metabolic enzymes and improving substrate availability for homocysteine degradation. Additionally, it has been suggested that prevention of folate depletion by vitamin E consumption decreases homocysteine levels. However, data on the effect of omega-3 fatty acids and/or vitamin E on homocysteine levels and nutritional status have been inconclusive. Therefore, this study was planned to examine the effect of combined supplementation of fish oil, as a source of omega-3 fatty acids, with wheat germ oil, as a source of vitamin E, on homocysteine and nutritional indices in hemodialysis patients. Methods: This study was a randomized, double-blind, placebo-controlled trial. Forty-six hemodialysis patients were randomly assigned to two equally-sized groups; a supplemented group who received 3000 mg/day of fish oil [1053 mg omega-3 fatty acids] plus 300 mg/day of wheat germ oil [0.765 mg vitamin E], and a matched placebo group who received placebo capsules for 4 months. Serum homocysteine and different nutritional indices were measured before and after the intervention. Results: Twenty patients in each group completed the study. At the end of the study, there were no significant changes in homocysteine levels and in the nutritional indices neither in the supplemented nor in the placebo-control groups (p > 0.05). Conclusions: Fish oil and wheat germ oil combination did not produce significant effects on serum homocysteine levels and nutritional indices of hemodialysis patients.


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