scholarly journals Tissue Velocity Imaging-Based Atrial Fibrillatory Cycle Length and Wall Motion for Predicting Atrial Structural Remodeling in Patients Undergoing Catheter Ablation

2014 ◽  
Vol 78 (7) ◽  
pp. 1619-1627 ◽  
Author(s):  
Kazumasa Sonoda ◽  
Yasuo Okumura ◽  
Ichiro Watanabe ◽  
Koichi Nagashima ◽  
Masayoshi Kofune ◽  
...  
2009 ◽  
Vol 20 (12) ◽  
pp. 1374-1381 ◽  
Author(s):  
CEES B. DE VOS ◽  
LAURENT PISON ◽  
RON PISTERS ◽  
ULRICH SCHOTTEN ◽  
EMILE C. CHERIEX ◽  
...  

Author(s):  
Reyhaneh Zavar ◽  
Hakimeh Sadeghian ◽  
Masoumeh Lotfi-Tokaldany ◽  
Mohammad Moein Ashrafi ◽  
Mahmood Sheikh Fathollahi ◽  
...  

 Introduction: Myocardial longitudinal tissue velocity imaging (TVI) and strain rate imaging (SRI) indices may have a role in the prediction of significant proximal stenosis of left anterior descending (LAD) by echocardiography. Materials And Methods: Total 20 patients with proximal LAD stenosis >70% by angiography and ejection fraction ≥50%, without wall motion abnormality at resting echo (stenotic group) and 20 angiographically normal coronaries subjects with normal echocardiography (non-stenotic group) were included in the study. SRI and TVI were performed in nine segments of the LAD territory at rest. Parameters of interest included: peak systolic strain (ST, %), strain rate (SR, Second-1), and peak systolic velocity (Sm, cm/s). Results: Overal mean ST and SR showed a significant reduction in the stenotic group compared to non-stenotic group (P<0.001), while the mean Sm had no significant difference. A segment-by-segment comparison revealed a reduction of ST in 4/9 (two apical and two anteroseptal) and SR in 5/9 (three apical, septal, and anteroseptal midportion) in the stenotic group (P<0.05). Both ST and SR showed a significant reduction in three segments: anterior-apical, lateral-apical, and anteroseptal-midportion. When both ST and SR decreased in one segment, specificity and sensitivity for the diagnosis of proximal LAD stenosis was more than 80% and 55%, respectively, by Roc analysis. Conclusion: There is an overall reduction in the mean ST and SR in the segments of LAD territory with significant proximal stenosis and normal wall motion at rest and an acceptable specificity and sensitivity of SRI for the detection of stenosis in these segments.


2011 ◽  
Vol 39 (02) ◽  
pp. 69-78 ◽  
Author(s):  
M. Killich ◽  
K. Hartmann ◽  
G. Wess

Zusammenfassung Ziele der Studie waren die Evaluierung der myokardialen Gewebegeschwindigkeit mittels Gewebe-Doppler (Tissue Velocity Imaging, TVI) hinsichtlich der Reproduzierbarkeit sowie die Erstellung von Referenzwerten für die systolische und diastolische longitudinale Myokardbewegung. Weiterhin wurde der Einfluss von Geschlecht, Herzfrequenz, Alter, Gewicht und Rasse untersucht. Material und Methoden: Das Probandenkollektiv umfasste 199 gesunde Hunde. Systolische und diastolische longitudinale TVI wurden mittels Farb-Gewebe-Doppler im linksapikalen Vierkammerblick für rechte freie Wand, Septum und linke freie Wand einzeln aufgezeichnet und ausgewertet. Ergebnisse: Die Variationskoeffizienten für die Intrareader-Variabilität lagen alle unter 10%. Die Variationskoeffizienten für die Interreader-Variabilität unterschritten 12,4%. Das TVI wies eine heterogene Verteilung im Myokard mit einem apikobasalen Geschwindigkeitsgradienten für systolische und diastolische Parameter auf. Es zeigte keine Abhängigkeit vom Geschlecht. Dagegen beeinflussten Herzfrequenz, Alter, Gewicht und Rasse das TVI signifikant. Schlussfolgerung und klinische Relevanz: Das TVI stellt eine Technik mit guter Reproduzierbarkeit dar. Nachteil des Verfahrens ist die Abhängigkeit von Herzfrequenz, Alter, Gewicht und Rasse der Hunde. Die Studie belegt, dass das TVI beim Hund als neue Methode in der Echokardiographie eingesetzt werden kann. Diese Arbeit stellt eine Grundlage für weitere Studien auf dem Gebiet der Gewebe-Dopplertechnik dar und liefert für den klinischen Einsatz Referenzwerte für Hunde verschiedener Gewichtsgruppen.


2013 ◽  
Vol 11 (1) ◽  
Author(s):  
Nina NE Elmstedt ◽  
Jonas JJ Johnson ◽  
Britta BL Lind ◽  
Kjerstin KFW Ferm-Widlund ◽  
Lotta LH Herling ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Jun Tanaka ◽  
Satoshi Nakatani ◽  
Makoto Amaki ◽  
Hideaki Kanzaki ◽  
Shuji Hashimoto ◽  
...  

Dilated cardiomyopathy (DCM) is histologically characterized by myocardial fibrosis and cellular hypertrophy. These myocardial changes may affect timing of regional peak contraction. We investigated whether there was a correlation between intraventricular septal (IVS) intramural asynchrony based on tissue velocity imaging and the histologic changes. We obtained apical 4-chamber tissue velocity images in 27 normal subjects and 22 patients with DCM undergoing myocardial biopsy using Vivid 7 (GE). We set 6 tandem regions of interest (ROIs) on the mid level of the IVS and measured the time to peak myocardial contraction (Ts) from the QRS onset at each ROI. We defined the standard deviation of Ts (Ts-SD) as an index of IVS asynchrony. Further, we analyzed a correlation between Ts-SD and the degree of myocardial fibrosis and cellular hypertrophy. The degree of myocardial fibrosis and cellular hypertrophy was graded qualitatively (0 to 3 scale) according to the percent of fibrosis occupied of the tissue sample and cell size. Ts-SD was larger in patients with DCM compared with normal subjects (13.9±12.3 vs. 6.2±4.0 ms, p<0.05), suggesting asynchronous contraction of IVS in DCM. Ts-SD showed a significant correlation with the degree of myocardial fibrosis (grade 1, 6.9±3.5 ms; grade 2, 15.7±3.5 ms; grade 3, 25.9±5.3 ms; p<0.05), while not with that of cellular hypertrophy (p=0.50). There was intramural asynchrony in IVS in DCM. This method could predict the degree of myocardial fibrosis noninvasively. Because myocardial fibrosis is the substrate for heart failure in DCM, the present method should provide clinically important information.


EP Europace ◽  
2014 ◽  
Vol 16 (11) ◽  
pp. 1546-1553 ◽  
Author(s):  
I. Limantoro ◽  
C. B. de Vos ◽  
T. Delhaas ◽  
B. Weijs ◽  
Y. Blaauw ◽  
...  

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Jiun Tuan ◽  
Suman Kundu ◽  
Mohamed Jeilan ◽  
Faizel Osman ◽  
Rajkumar Mantravadi ◽  
...  

Introduction & Hypothesis: Studies in catheter ablation of atrial fibrillation (AF) show that an increase in cycle length (CL) and higher organization index (OI) is associated with termination of AF. We hypothesize that similar changes can be seen in chemical cardioversion with Flecainide Methods: Patients who were still in AF at the end of catheter ablation for AF were given intravenous flecainide. OI and dominant frequency (DF) were obtained by Fast Fourier Transform of coronary sinus electrograms over 10s in AF, before and after flecainide infusion. Mean CL was also calculated. Results: 28 patients were identified (18 paroxysmal AF and 10 persistent AF). 8 cardioverted to sinus rhythm (SR) with flecainide. In all patients, mean CL increased from 211 ± 44 ms to 321 ± 85 ms (p <0.001). Mean DF decreased from 5.2 ± 1.03 Hz to 3.6 ± 1.04 Hz (p <0.001). Mean OI was 0.33 ± 0.13 before and 0.32 ± 0.11 after flecainide (p = 0.90). Comparing patients who cardioverted to SR with those who did not, OI post-flecainide was 0.41 ± 0.12 vs 0.29 ± 0.10 (p=0.013) and relative change in OI was 29 ± 33% vs −3.9 ± 27% (p=0.016) respectively. No significant difference was noted in the change in CL and DF in the 2 groups. Logistic regression showed that a greater relative increase in OI (p=0.04), a higher OI post-flecainide (p=0.03) and SR at start of procedure (p=0.03) are independently associated with cardioversion to SR with flecainide. Conclusion: Increase in OI, independent of changes to the CL and DF, appears critical to AF termination with flecainide. The increase in OI may reflect an increase in size and reduction in the number of re-entrant circuits, which together with slowing of atrial activation, result in return to SR.


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