scholarly journals Longitudinal Tissue Velocity and Deformation Imaging in Patients with Significant Stenosis of Left Anterior Descending Artery

Author(s):  
Reyhaneh Zavar ◽  
Hakimeh Sadeghian ◽  
Masoumeh Lotfi-Tokaldany ◽  
Mohammad Moein Ashrafi ◽  
Mahmood Sheikh Fathollahi ◽  
...  

 Introduction: Myocardial longitudinal tissue velocity imaging (TVI) and strain rate imaging (SRI) indices may have a role in the prediction of significant proximal stenosis of left anterior descending (LAD) by echocardiography. Materials And Methods: Total 20 patients with proximal LAD stenosis >70% by angiography and ejection fraction ≥50%, without wall motion abnormality at resting echo (stenotic group) and 20 angiographically normal coronaries subjects with normal echocardiography (non-stenotic group) were included in the study. SRI and TVI were performed in nine segments of the LAD territory at rest. Parameters of interest included: peak systolic strain (ST, %), strain rate (SR, Second-1), and peak systolic velocity (Sm, cm/s). Results: Overal mean ST and SR showed a significant reduction in the stenotic group compared to non-stenotic group (P<0.001), while the mean Sm had no significant difference. A segment-by-segment comparison revealed a reduction of ST in 4/9 (two apical and two anteroseptal) and SR in 5/9 (three apical, septal, and anteroseptal midportion) in the stenotic group (P<0.05). Both ST and SR showed a significant reduction in three segments: anterior-apical, lateral-apical, and anteroseptal-midportion. When both ST and SR decreased in one segment, specificity and sensitivity for the diagnosis of proximal LAD stenosis was more than 80% and 55%, respectively, by Roc analysis. Conclusion: There is an overall reduction in the mean ST and SR in the segments of LAD territory with significant proximal stenosis and normal wall motion at rest and an acceptable specificity and sensitivity of SRI for the detection of stenosis in these segments.

Author(s):  
Hakimeh Sadeghian ◽  
Parastoo Vosoughi ◽  
Afsaneh Sadeghian ◽  
Masoumeh Lotfi-Tokaldany ◽  
Mohammad Moein Ashrafi ◽  
...  

Introduction: The use of tissue velocity and strain rate imaging is proposed for the quantification of non-viable myocardium. This study is aimed at investigating the differences in tissue velocity and strain rate imaging indices between non-viable left ventricular apical segments and the normal segments using segment-by-segment comparison.Materials and Method: Thirty-two patients with akinetic left ventricular apical segments and without viability were selected using two-dimensional echocardiography and dobutamine stress echocardiography; 32 individuals with normal echocardiography and coronary angiography formed the normal group. Peak systolic velocity, peak systolic strain, and strain rate were measured in the four left ventricular apical segments and the apex 17th segment.Results: The patient group had a significantly lower ejection fraction (26.88±6.06% vs. 56.56±2.36%; p<0.001). Overall, the patient group had significantly lower resting peak systolic velocity, systolic strain, and strain rate. In the segment-by-segment comparison, only systolic strain showed a remarkable reduction in the patient group, while reduction in Sm and strain rate were not significant in all the segments. After dobutamine stress echocardiography, only systolic strain showed an insignificant increase compared to the resting values. In the apex 17th segment, Sm showed significant reduction in the patient group.Conclusion: The ST in apical segments may be used as a quantitative index for detecting akinesia both at rest and after dobutamine infusion. Reduction in Sm can be used as a marker of akinesia in the apical cap at rest.


2003 ◽  
Vol 41 (6) ◽  
pp. 494 ◽  
Author(s):  
Azaria J.J.T. Rein ◽  
Zeev Perles ◽  
Amiram Nir ◽  
Ikuo Hashimoto ◽  
Xiaokui Li ◽  
...  

Author(s):  
Azam Safir‐Mardanloo ◽  
Mani Khorsand Askari ◽  
Masoumeh‐ Lotfi Tokaldany ◽  
Mohammad Moein Ashrafi ◽  
Hakimeh Sadeghian

2014 ◽  
Vol 78 (7) ◽  
pp. 1619-1627 ◽  
Author(s):  
Kazumasa Sonoda ◽  
Yasuo Okumura ◽  
Ichiro Watanabe ◽  
Koichi Nagashima ◽  
Masayoshi Kofune ◽  
...  

2009 ◽  
Vol 20 (12) ◽  
pp. 1374-1381 ◽  
Author(s):  
CEES B. DE VOS ◽  
LAURENT PISON ◽  
RON PISTERS ◽  
ULRICH SCHOTTEN ◽  
EMILE C. CHERIEX ◽  
...  

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
I. Garba ◽  
M.Z. Ibrahim ◽  
S. Lawal ◽  
N.D. Chom ◽  
P.O. Ibinaiye

Cervical cancer remains an important health issue especially in the developing countries that account for about 85% of the world burden of cervical cancer. Finding a role for Doppler ultrasound in the evaluation of these patients, may reduce the cost and improve access to management. This study was aimed at evaluating the Doppler flow parameters in patients with cervical cancer when compared to normal subjects. This was a prospective case control, descriptive and observational study conducted in radiology department, ABU Teaching Hospital, Zaria, Nigeria. Eighty-one patients with cervical cancer and 81 age-matched controls had transabdominal Doppler ultrasound examination of the main uterine arteries. The data was analyzed using SPSS version 20.0 Chicago Illinois USA. Difference between two groups was tested using student ttest and P<0.05 considered as statistically significant. The mean Resistivity Index (RI) and Pulsatility Index (PI) were significantly lower in patients with cervical cancer than the control (P<0.0001). The mean end diastolic velocity was significantly higher in patients than the control (P<0.0001). There was however no significant difference in the mean peak systolic velocity in patients and control (P=0.97). The findings have demonstrated that significant differences exist in the uterine artery Doppler flow parameters in patients with cervical cancer compared to the healthy controls. This emphasizes the role of Doppler scan in the evaluation and management of patients with cervical cancer.


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