scholarly journals Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT1

2020 ◽  
Vol 93 (0) ◽  
pp. 1-SS-64
Author(s):  
Kou Nishikubo ◽  
Ryuichi Ohgaki ◽  
Hiroki Okanishi ◽  
Suguru Okuda ◽  
Yoshikatsu Kanai
Keyword(s):  
Amino Acid ◽  
Cancer Cells ◽  
Signaling Pathways ◽  
Time Course ◽  
Amino Acid Transporter ◽  
Cancer Type ◽  
Intracellular Amino Acid ◽  
Acid Transporter ◽  
Amino Acid Concentrations

scholarly journals Comparative phosphoproteomics between non-competitive and competitive inhibitions of L-type amino acid transporter 1 in cancer cells.

2019 ◽  
Vol 92 (0) ◽  
pp. 1-P-106
Author(s):  
Pornparn Kongpracha ◽  
Pattama Wiriyasermkul ◽  
Yoko Tanaka ◽  
Suguru Okuda ◽  
Ryuichi Ohgaki ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Transporter ◽  
Acid Transporter

scholarly journals Anti‐tumor effects of an antagonistic mAb against the ASCT2 amino acid transporter on KRAS ‐mutated human colorectal cancer cells

2019 ◽  
Vol 9 (1) ◽  
pp. 302-312 ◽  
Author(s):  
Yuta Hara ◽  
Yushi Minami ◽  
Soshi Yoshimoto ◽  
Natsumi Hayashi ◽  
Akitaka Yamasaki ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Transporter ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Acid Transporter ◽  
Human Colorectal Cancer Cells

A Selective and Slowly Reversible Inhibitor of l-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

2016 ◽  
Vol 59 (12) ◽  
pp. 5740-5751 ◽  
Author(s):  
Kristiina M. Huttunen ◽  
Mikko Gynther ◽  
Johanna Huttunen ◽  
Elena Puris ◽  
Julie A. Spicer ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cancer Cells ◽  
Drug Efficacy ◽  
Amino Acid Transporter ◽  
Reversible Inhibitor ◽  
Acid Transporter

scholarly journals Downregulation of L-type amino acid transporter 1 expression inhibits the growth, migration and invasion of gastric cancer cells

2013 ◽  
Vol 6 (1) ◽  
pp. 106-112 ◽  
Author(s):  
LIANGHUI SHI ◽  
WENPING LUO ◽  
WENBING HUANG ◽  
SHISUI HUANG ◽  
GUANGYAN HUANG
Keyword(s):  
Gastric Cancer ◽  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Transporter ◽  
Migration And Invasion ◽  
Gastric Cancer Cells ◽  
Acid Transporter

scholarly journals Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells

2019 ◽  
Vol 294 (11) ◽  
pp. 4012-4026 ◽  
Author(s):  
Angelika Bröer ◽  
Gregory Gauthier-Coles ◽  
Farid Rahimi ◽  
Michelle van Geldermalsen ◽  
Dieter Dorsch ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cancer Cells ◽  
Amino Acid Transporter ◽  
Neutral Amino Acid ◽  
Gene Encoding ◽  
Neutral Amino Acid Transporter ◽  
Acid Transporter
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