scholarly journals Prompt gamma imaging for the identification of regional proton range deviations due to anatomic change in a heterogeneous region

2020 ◽  
Vol 93 (1116) ◽  
pp. 20190619
Author(s):  
Yunhe Xie ◽  
Johannes Petzoldt ◽  
Guillaume Janssens ◽  
Fionnbarr O'Grady ◽  
Lingshu Yin ◽  
...  
Keyword(s):  
Treatment Plan ◽  
Patient Treatment ◽  
Prompt Gamma ◽  
Target Region ◽  
Sinus Cavity ◽  
Anatomic Change ◽  
Cavity Filling ◽  
Heterogeneous Region ◽  
Prompt Gamma Imaging ◽  
Range Verification

Objectives: Prompt gamma (PG) imaging has previously been demonstrated for use in proton range verification of a brain treatment with a homogeneous target region. In this study, the feasibility of PG imaging to detect anatomic change within a heterogeneous region is presented. Methods: A prompt gamma camera recorded several fractions of a patient treatment to the base of skull. An evaluation CT revealed a decrease in sinus cavity filling during the treatment course. Comparison of PG profiles between measurement and simulation was performed to investigate range variations between planned and measured pencil beam spot positions. Results: For one field, an average over range of 3 mm due to the anatomic change could be detected for a subset of spots traversing the sinus cavity region. The two other fields appeared less impacted by the change but predicted range variations could not be detected. These results were partially consistent with the simulations of the evaluation CT. Conclusion: We report the first clinical application of PG imaging that detected some of the expected small regional proton range deviations due to anatomic change in a heterogeneous region. However, several limitations exist with the technology that may limit its sensitivity to detect range deviations in heterogeneous regions. Advances in knowledge: We report on the first detection of range variations due to anatomic change in a heterogeneous region using PGI. The results confirm the feasibility of using PG-based range verification in highly heterogeneous target regions to identify deviations from the treatment plan.

scholarly journals OC-0566 Range verification in proton therapy: Can prompt-gamma imaging identify the source of deviation?

2019 ◽  
Vol 133 ◽  
pp. S296-S297
Author(s):  
C. Khamfongkhruea ◽  
G. Janssens ◽  
J. Petzoldt ◽  
J. Smeets ◽  
G. Pausch ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Prompt Gamma ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Range Verification

scholarly journals 3D prompt gamma imaging for proton beam range verification

2018 ◽  
Vol 63 (3) ◽  
pp. 035019 ◽  
Author(s):  
E Draeger ◽  
D Mackin ◽  
S Peterson ◽  
H Chen ◽  
S Avery ◽  
...  
Keyword(s):  
Proton Beam ◽  
Prompt Gamma ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Beam Range ◽  
Range Verification

Prompt Gamma Imaging for In Vivo Range Verification of Pencil Beam Scanning Proton Therapy

2017 ◽  
Vol 99 (1) ◽  
pp. 210-218 ◽  
Author(s):  
Yunhe Xie ◽  
El Hassane Bentefour ◽  
Guillaume Janssens ◽  
Julien Smeets ◽  
François Vander Stappen ◽  
...  
Keyword(s):  
Proton Therapy ◽  
Prompt Gamma ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Gamma Imaging ◽  
Pencil Beam Scanning ◽  
Prompt Gamma Imaging ◽  
Range Verification

TU-FG-BRB-05: A 3 Dimensional Prompt Gamma Imaging System for Range Verification in Proton Radiotherapy

2016 ◽  
Vol 43 (6Part35) ◽  
pp. 3757-3757
Author(s):  
E Draeger ◽  
H Chen ◽  
D Mackin ◽  
S Peterson ◽  
S Avery ◽  
...  
Keyword(s):  
Imaging System ◽  
Prompt Gamma ◽  
Proton Radiotherapy ◽  
3 Dimensional ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Range Verification

MO-FG-CAMPUS-JeP1-02: Proton Range Verification of Scanned Pencil Beams Using Prompt Gamma Imaging

2016 ◽  
Vol 43 (6Part31) ◽  
pp. 3717-3717 ◽  
Author(s):  
Y Xie ◽  
E Bentefour ◽  
G Janssens ◽  
J Smeets ◽  
D Dolney ◽  
...  
Keyword(s):  
Prompt Gamma ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Range Verification

scholarly journals Correction of Geometrical Effects of a Knife-Edge Slit Camera for Prompt Gamma-Based Range Verification in Proton Therapy

Instruments ◽  
2018 ◽  
Vol 2 (4) ◽  
pp. 25 ◽  
Author(s):  
Johannes Petzoldt ◽  
Guillaume Janssens ◽  
Lena Nenoff ◽  
Christian Richter ◽  
Julien Smeets
Keyword(s):  
Proton Therapy ◽  
Patient Treatment ◽  
Prompt Gamma ◽  
Knife Edge ◽  
Correction Model ◽  
System A ◽  
Safety Margins ◽  
Geometrical Effects ◽  
Edge Slit ◽  
Range Verification

Prompt gamma (PG) based range verification can potentially reduce the safety margins in proton therapy. A knife-edge slit camera has been developed in this context using analytical PG simulations as reference for absolute range verification during patient treatment. Geometrical deviations between measurement and simulation could be observed and have to be corrected for in order to improve the range retrieval of the system. A geometrical correction model is derived from Monte Carlo simulations in water. The influence of different parameters is tested and the model is validated in a dedicated benchmark experiment. We found that the geometrical correction improves the agreement between measured and simulated PG profiles resulting in an improved range retrieval and higher accuracy for absolute range verification. An intrinsic offset of 1.4 mm between measurement and simulation is observed in the experimental data and corrected in the PG simulation. In summary, the absolute range verification capabilities of a PG camera have been improved by applying a geometrical correction model.

Time-of-flight neutron rejection to improve prompt gamma imaging for proton range verification: a simulation study

2012 ◽  
Vol 57 (20) ◽  
pp. 6429-6444 ◽  
Author(s):  
Aleksandra K Biegun ◽  
Enrica Seravalli ◽  
Patrícia Cambraia Lopes ◽  
Ilaria Rinaldi ◽  
Marco Pinto ◽  
...  
Keyword(s):  
Simulation Study ◽  
Time Of Flight ◽  
Prompt Gamma ◽  
Gamma Imaging ◽  
Prompt Gamma Imaging ◽  
Range Verification

Aesthetic Crown Lengthening for Gummy Smile Treatment Related to Altered Passive Eruption: A Case Report

2020 ◽  
Vol 23 (2) ◽  
pp. 28-33
Author(s):  
Indira Apriantika ◽  
Agung Krismariono
Keyword(s):  
Case Report ◽  
Treatment Plan ◽  
Patient Treatment ◽  
Treatment Results ◽  
Dental Hospital ◽  
Proper Diagnosis ◽  
The Aesthetic ◽  
Smile Aesthetics ◽  
Crown Lengthening ◽  
Gummy Smile

A healthy and beautiful smile can affect appearance and confidence. One of the aesthetic problems in dentistry that is often complained of by patients is excessive gingival display (gummy smile). The excessive gingival display can be caused by several factors, one of which is altered passive eruption (APE). One of the treatments to correct gummy smile related to APE is crown lengthening. Crown lengthening can be with bone reduction (gingivectomy with bone reduction) or without bone reduction (gingivectomy). Crown Lengthening with bone reduction is a surgical procedure that aims to maintain the dentogingival complex and to improve smile aesthetics. The purpose of this case report is to determine the crown lengthening with bone reduction (gingivectomy with bone reduction) procedure as a gummy smile treatment related to APE .A23-year-old female patient, came to Dental Hospital of Universitas Airlangga with complaints of her upper gum which not in the same length and the teeth looked short, she considered her smile was less aesthetic. After conducting analyses relating to aesthetics and periodontal tissue, crown lengthening with bone reduction was chosen for this patient treatment. The treatment results are quite good, visible gingival margins that matched the gingival zenith and improved patient's smile profile. APE as the etiology of patient's gummy smile can be corrected. There are no post-surgical complications such as excessive pain and infection. A proper diagnosis, treatment plan, and good techniques can produce a harmonious smile on the patient.

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